93 results about "Artificial Implants" patented technology

A new lens design and method of implantation uses the change in pupil diameter of the eye concurrent with the changes induced by a contraction of the ciliary muscle during the accommodative reflex, in order to assist in focusing of nearby objects. This new intraocular lens consists of two parts. The posterior part or haptic part is inserted behind the iris and in front of the natural lens or artificial implant. Its main purpose is to participate in the accommodative mechanism and to prevent excessive lateral movement and luxation of the lens. An anterior or optical part is made of flexible material and is placed before the iris. Its diameter is variable but should be large enough to cover the pupillary margins to some degree under various conditions of natural dilation. The anterior and posterior part of the lens are separated by a compressible circular groove in which the iris will settle. The diameter of this groove is slightly larger than the pupillary diameter measured under normal photopic daylight conditions and for distance vision. Since the pupil becomes smaller in near vision, the iris will exert a slight pressure at the level of the groove of the lens which will cause a progressive and evenly distributed flexing of the anterior part of the intraocular lens, as the diameter of the compressible circular groove slightly decreases. This flexing will induce an increase in refractive power which corresponds to a variable part of the amount necessary for focusing nearby objects.

A system improves the design of artificial implant components for use in joint replacement surgeries. The system includes an anthropometric static image data analyzer, an implant model data generator, a kinematic model simulator, and a dynamic response data analyzer. The implant model data generator may also use image data of a joint in motion for modification of the implant model data used in the kinematic simulation. Dynamic response data generated by the kinematic model simulation is analyzed by the dynamic response data analyzer to generate differential data that may be used to further refine the implant model data.

A system improves the design of artificial implant components for use in joint replacement surgeries. The system includes an anthropometric static image data analyzer, an implant model data generator, a kinematic model simulator, and a dynamic response data analyzer. The implant model data generator may also use image data of a joint in motion for modification of the implant model data used in the kinematic simulation. Dynamic response data generated by the kinematic model simulation is analyzed by the dynamic response data analyzer to generate differential data that may be used to further refine the implant model data.

Artificial implants having reduced area to provide reduced wear are provided. The reduced area is particularly located at areas where greatest wear is exhibited. In a particular embodiment of a mobile bearing knee implant, the area is reduced on the mobile bearing insert underside, where it contacts a tibial component. The reduced area may be any shape of indentations, for example, grooves, dimples, straight patterns, curved patterns, crossing patterns, holes, channels or slots. The indentations may be various sizes, and have been found to be particularly effective if covering about 10% to about 20% of the insert at depths between about 1-2 mm.

Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

The present invention relates to a method for manufacturing artificial implants, comprising 1) acquiring the pre-operation three dimensional volume image and the post-operation three dimensional volume image of the operation portion, thereby respectively producing the pre-operation target image and the post-operation target image including the target; 2) aligning the pre-operation target image with the post-operation target image so as to generate the aligned image; 3) acquiring the difference image of the incised part in the target based on the aligned image; 4) building the three dimensional model of mold points of the incised part based on the difference image; and 5) manufacturing the artificial implant having the same shape with the incised part based on such three dimensional model of mold points.

Prosthetic implant of the type comprising: a tubular support (12) of axis X, which can be deformed between a compressed state with a small diameter and a dilated state with a larger diameter, the tubular support comprising a lattice comprising rhombus-shaped meshes (26), each mesh having a first diagonal (28) parallel to the axis X and a second diagonal (32) perpendicular to the axis X; and at least one resilient membrane (14A, 14B) arranged inside the tubular support. The membrane comprises a fixing portion (48, 52), the fixing portion being fixed to a fixing section (65, 66) delimited by a strand (20A, 20B) of the tubular support, the fixing section being oriented substantially parallel to the axis X.

Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

A hydrogel-metal assembly is provided. An intervening polymer network is used to bond together a water-swollen hydrogel layer and a biocompatible surface-modified metallic layer. The hydrogel layer is a water-swollen hydrogel layer of at least two interpenetrating polymers. The surface of the biocompatible surface-modified metallic layer is surface-modified with an inorganic material. The intervening polymer network has been chemically grafted to the inorganic material of the biocompatible surface-modified metallic layer through bi-functional linker molecules. The intervening polymer network is further physically or chemically cross-linked with the polymers of the water-swollen hydrogel. The hydrogel-metal assembly can be adapted to form a medical device, medical implant, an artificial implant, an orthopedic implant, or at least as part of a joint. The hydrogel-metal assembly is attractive for use as such implants or devices due to its characteristics such as, for example, low coefficient of friction, impact-absorption capacity or strength, and / or biocompatibility.

The invention discloses an implant surface biomimetic coating material for promoting the sacralization and a preparation method thereof. The coating material is a compound of calcium phosphate cooperatively doped with various trace elements and organic macromolecules. The preparation method comprises the following steps of: immersing an artificial implant pretreated by acid or alkali in simulated body fluid containing various trace element ions and organic macromolecules; carrying out chemical precipitation treatment between 35 DEG C and 150 DEG C to ensure that the surface of the implant is subjected to calcium phosphate salt core forming and growth; and forming a continuous coating of calcium phosphate salt cooperatively doped with various trace elements and the organic macromolecules. The surface of the coating has a nanoscale fine structure, and the effects of slowly degrading and releasing active ions of calcium, phosphorus and various trace elements and promoting the sacralization of implants for diseased intraosseous injuries, bone fracture internal fixation and tooth root internal fixation in the oral cavity. The coating material has the characteristics of simple preparation process, controllable coating thickness, trace element content, crystallinity and degradation rate, and the like.

The present invention discloses a surface treatment method of a dental implant, wherein a titanium or titanium alloy artificial implant is used. Through partial treatments which comprise sand spraying, acid pickling and coating hydroxyl calcium phosphate with biocompatibility, a specific porous structure is generated on the surface of the artificial dental implant, and the artificial dental implant is also provided with a partial porous hydroxyl calcium phosphate coating. Therefore osteoblast-like cell and bone integration speed can be increased, and furthermore the treatment period in artificial tooth implantation is reduced.

The invention discloses a function gradient bionic structure titanium alloy artificial implant and a forming method thereof. Based on the special service performance demand of the human body skeletonand the enlightenment of the high performance of a honeycomb space porous structure in nature, by combining the excellent anti-bacterial performance of metal silver nanoparticles in the human body, and by means the advanced laser additive manufacturing technology, the low-modeling gradient bionic structure titanium alloy artificial implant with a high anti-bacterial performance function is precisely formed. According to the function gradient bionic structure titanium alloy artificial implant and the forming method thereof, the integrated manufacturing of the titanium alloy artificial implant with a bionic structure and the anti-bacterial function is achieved, the manufacturing efficiency is greatly improved, the production cost is effectively reduced, and good economic benefits are achieved; and on the other hand, the titanium alloy artificial implant manufactured through the method achieves the excellent mechanical performance and the anti-bacterial performance, the biocompatibility and the service performance of the implant are remarkably improved, and wide market prospects are achieved.

The invention discloses a preparation method of a nanometer zirconia particle toughened biological titanium alloy porous artificial implant. The preparation method is characterized by comprising the following steps: (1) preparation of nanometer / micron mixed powder: nanometer zirconia powder with a mass fraction of 0.5-8% is weighed and added in remained micron-grade titanium alloy powder, and the two powder is uniformly mixed by using a mechanical mixing method, wherein the particle size of the titanium alloy powder is 1-50 microns, and the purity is not lower than 99%; the size of the zirconia powder is 10-100 nm; and zirconia contains a yttrium oxide stabilizing agent with 1-5% of the mass of the zirconia powder; and (2) a matched porous artificial implant model is designed according to different personal demands by using three-dimensional design software; the designed three-dimensional data model is introduced in a computer for layering and slicing to obtain profile information of each layer; the mechanically mixed powder is paved on a forming cylinder by using a powder paving device; and the area selective melting formation is performed by using laser or electronic beams. The implant has the characteristics of good toughness and high biological compatibility.

A medicine applying artificial implanted body is composed of a hollow main body with meshes for releasing medicine, a medicine bag in said main body, and a screw cover for enclosing said main body.

The invention belongs to the technical field of artificial implant, in particular, to a method for designing implant prosthesis, which comprises the following steps: a) providing a reference fixture in a mouth cavity; b) scanning: scanning the inside of the mouth cavity, obtaining digital data and then storing into a computer; c) locating: obtaining digital implant prosthetic positioning and connection interfaces with the configuration of digital data; and d) adjusting and designing: adjusting digital implant prosthesis, so as to obtain the implant prosthesis suitable for a patient. The invention has the following advantages of 1. a mouth cavity solid model needs not be reproduced, production time and cost are saved, the reproduction of the distortion caused by model is avoided to obtain more accurate prosthetic implant; 2. the connection interface of the implant is more obvious, a relationship between the digital implant prostheses and the implant is more precise, the most appropriate type of the prosthetic implant is regulated, a clear relationship between the teeth on the bite information is obtained and the accuracy of dentures on bite is improved.

The invention discloses a regenerated active artificial implant for osteoporosis therapy and a preparation method thereof. The regenerated active man-made implant comprises a tooth implant with titanium or titanium alloy as a base and an artificial bone joint medical hard tissue implant material. The base material surface is subjected to serial nano-micron treatment and simvastatin-containing improved bionic liquid treatment to form a nano bionic coating structure with regeneration activity and bone mass formation promoting effect; the nano coating crystal grains on the surface of the implant are bone-like hydroxyapatite substance rich in calcium and phosphorous; the nano-micron bionic coating implant has bone regeneration promoting activity and high affinity, and compared with coating-free materials, the nano-micron bionic coating implant has remarkably increased binding force with bone so as to effectively prevent the implant from loose and fallout phenomena; the simvastatin-containing calcium / phosphorus bionic coating implant is a novel medical implant material with bone mass formation promoting effect and regeneration activity.

The present invention belongs to the field of anticoagulant material technology. The anticoagulant surface modification process of artificial implant includes the following steps: cleaning artificial implant; preparing silicone rubber solution; coating the artificial implant with medical silicone rubber as support; coating perfluoro sulfonic acid on the surface of the silicone rubber coating; depositing polycation and polyanion alternately onto the surface of the perfluoro sulfonic acid coating via electrostatic attraction; and irradiating the artificial implant with ultraviolet light to produce photochemical reaction to convert the ionic bond between coating layers into covalent bond. The present invention has simple technological process, mild reaction condition, easy operation, high repeatability, environment friendship and thus excellent application foreground.

A composition comprising bone marrow cells (BMC) and demineralized bone matrix (DBM) or demineralized tooth matrix (DTM), together with a site-responsive polymer, optionally further comprising bone morphogenetic proteins (BMP) and / or other active agents, particularly for use in the transplantation of mesenchymal progenitor cells into a joint or a cranio-facial-maxillary bone, alveolar bone of maxilla and mandibula, spine, pelvis or long bones, or for construction or reconstruction of any extra skeletal bone, including for mechanical or biological support of artificial implants to the joint or of the joint or to the bone, for restoring and / or enhancing the formation of a new hyaline cartilage and subchondral bone structure. A kit is provided for performing transplantation of the composition into a joint, maxillary or mandibular alveolar bone or any bony structure of a mammal, including support of artificial implants.

The invention discloses an artificial implant for the carpometacarpal joint. The artificial implant is used for arthroplasty of the carpometacarpal joint surface of the first metacarpal bone and comprises an insert portion, an arthroplasty portion and an attached flange. The insert portion is provided with an insert end and a front end, the insert end is inserted into a marrow cavity exposed in an incision of the first metacarpal bone. The arthroplasty portion is connected to the front end of the insert portion and arranged outside the incision of the first metacarpal bone and is provided with a joint profile surface so as to substitute for the carpometacarpal joint surface of the first metacarpal bone. The attached flange is convexly arranged at a rim of the arthroplasty portion and used for flatly attaching to an exoskeleton surface of the incision adjacent to the first metacarpal bone. Besides, the attached flange is provided with at least one suture through hole for at least one suture to pass, so that abductor pollicis longus can be assisted in being fixed to the surface of the exoskeleton.

The invention relates to a dental implant, in particular to a dental implant implantation method which comprises the following steps of S1, rubbing an oral cavity model of a patient; S2, preparing a hole in an alveolar bone, and implanting an artificial implant; S3, waiting for synostosis; S4, installing a healing abutment to enable the implant to penetrates through a gingiva, and waiting for formation of soft tissues; S5, preparing a locator according to the oral cavity model of the patient; S6, after formation of the soft tissues, dismantling the healing abutment, putting the locator and a permanent abutment at the implantation part of the patient after the locator and a permanent abutment are matched to enable the locator to be matched with teeth and the gingivae on the two sides of theimplantation part, and installing an abutment fixing bolt from an installation hole to fix the permanent abutment on the implant; and S7, wearing a dental crown on the permanent abutment. By adoptingthe dental implant implantation method provided by the invention, the locator is adopted to assist location when the permanent abutment is installed, and the effect of accurately locating and installing the position of the permanent abutment is achieved.

The invention provides a titanium / hydroxyl apatite biological composite material and the preparing method thereof, relating to a biomaterial and the preparing technology thereof for the orthopaedics, which solves the problems that the present artificial implant is lack of bone inductivity and bone conductibility whose surface is not good for the bone cell growing and adhesion, and as the mismatching of the implant and the elastic modulus of the bone tissue with the mechanical property, the bone is not completely loaded, causing the stress shield and obstructing the growing and restitution of the bone tissue. The titanium / hydroxyl apatite biological composite material consists of the titanium and hydroxyl apatite, whose preparing method is as follows: mixing the titanium metal powder with the hydroxyl apatite powder, then filling into a agate jar and ball milling for 3 to 6 hours in the atmosphere of argon gas; after that, taking out and cold pressing to mold in the room temperature, sintering the cold press molding composite material with the plasma sintering technology; then, keeping the temperature for 0 to 30 minutes; finally, cooling down to the room temperature following the furnace. The titanium / hydroxyl apatite biological composite material is extensively applicable to the restoration of the bone tissue in medicine.

The invention discloses a dental artificial implant and a production method thereof. The dental artificial implant comprises a tooth root and a tooth column, wherein the tooth root is a columnar body, the outer edge of the columnar body is provided with a screw thread part, the surface of the tooth root is processed by sandblasting to form a plurality of first pores and second pores on the surface of the tooth root, the tooth column stretches from the top of the tooth root, one or more mark parts and tabling grooves are formed at the outer edge, and a supported hole is arranged in the top of the tooth column. According to the invention, by carrying out sandblasting on the surface of the tooth root, a plurality of pores are formed on the surface of the tooth root, so that after tooth implantation, bone cells in the body bone tissue can be allowed to effectively penetrate into the first pores and the second pores and can generate radial grasping effect with the first pores and second pores, and then mutual grasping effect between the artificial implant and the bone tissue is strengthened.

The present invention relates to a method for manufacturing artificial implants, comprising 1) acquiring the pre-operation three dimensional volume image and the post-operation three dimensional volume image of the operation portion, thereby respectively producing the pre-operation target image and the post-operation target image including the target; 2) aligning the pre-operation target image with the post-operation target image so as to generate the aligned image; 3) acquiring the difference image of the incised part in the target based on the aligned image; 4) building the three dimensional model of mold points of the incised part based on the difference image; and 5) manufacturing the artificial implant having the same shape with the incised part based on such three dimensional model of mold points.

The present invention discloses a prosthesis based on a connection structure of a porous surface structure and a substrate. The connection structure comprising: a composite body comprising the poroussurface structure and an intermediate connected in advance; the substrate which is used for forming a prosthesis main body, wherein the surface of the prosthesis main body is taken a connecting area and is connected with the composite body; and the intermediate which is located between the porous surface structure and the substrate, and is connected with the connecting area of the prosthesis mainbody, so that the porous surface structure is located in the connectingarea of the prosthesis main body; wherein the substrate and the composite body are arranged between a first polar electrode and asecond polar electrode, and are in electric contact with the porous surface structure and / or the intermediate through the first polar electrode, and the substrate is in electric contact with the second polar electrode, so that a current loop is formed, and resistance welding of the intermediate and the substrate is realized. The composite body and the substrate are connected through a resistancewelding method, and the mechanical property of the substrate is kept; it is ensured that the artificial implant prosthesis has excellent bone ingrowth performance, and the strength of the substrate isnot substantially affected.

The invention discloses a connection structure of a porous surface structure and a substrate, a preparation method and a prosthesis. A high polymer material layer is arranged in a gap between the porous surface structure and the substrate, so that the porous surface structure is tightly connected with the substrate, the basic strength of the connecting structure is ensured, the stress shielding phenomenon is improved, and the problem of postoperative osteolysis is solved; wherein a pre-connected complex is arranged on the substrate, the pre-connected complex comprises another porous structureand an intermediate which are connected in advance, the pre-connected complex and the substrate are combined in advance through various methods, and then the substrate with the pre-connected complex is tightly connected with the porous surface structure through a high polymer material layer. Relative movement and even falling between a structure body formed by the high polymer material layer and the porous structure on the surface of the high polymer material layer and the substrate with a smooth surface can be prevented; on the basis of the surface of the porous structure, it can be guaranteed that the surface of the artificial implant prosthesis has excellent bone ingrowth performance, the strength of the substrate is not substantially affected, and the rigidity of the overall compositestructure is optimized to reduce the stress shielding risk.

The invention relates to a dental implant capable of grafting bones and belongs to the technical field of dentistry implantation. The dental implant is applied to gap filling after a tooth is cured through an operation and pulled out, and an artificial implant tooth can be fixed on a gum fast and firmly. The dental implant is provided with a dental implant body which is provided with a through hole structure. An inner wall and an outer wall of the dental implant body are communicated with each other through various hole grooves in regular and irregular shapes. The bones can be grafted in the through hole and the hole grooves of the dental implant body. Due to the fact that the dental implant has the through hole and the hole groove structure, bone mass can be filled inside the through hole and the hole grooves, and combination of the dental implant body and a gum bone is quickened. After the filling bone mass is fused with the gum bone, the combination strength is high compared with the existing simple combination of the outer surface of the implant body and the gum bone, and combination of the dental implant body and the gum is firm. Due to the fact that bone tissues can penetrate through the inside and the outside of the dental implant to grow, and survival rate of the dental implant in the gum is greatly increased.

A composition comprising bone marrow cells (BMC) and demineralized bone matrix (DBM) and / or mineralized bone matrix (MBM) and optionally comprising bone morphogenetic protein / s (BMP) and / or other active agents, particularly for use in the transplantation of mesenchymal progenitor cells into a joint and / or a cranio-facial maxillary bone, for restoring and / or enhancing the formation of a new hyaline cartilage and subchondral bone structure. The composition of the invention and method of treatment employing the same may be used for the treatment of hereditary or acquired bone disorders, hereditary or acquired cartilage disorders, malignant bone or cartilage disorders, metabolic bone diseases, bone infections, conditions involving bone or cartilage deformities and Paget's disease. The composition and method may further be used for the correction of complex fractures, bone replacement and formation of new bone in plastic or sexual surgery, for support of implants of joints, cranio-facial-maxillary bones, or other musculoskeletal implants, including artificial implants. The method of the invention may further be used for treating damaged joints or degenerative arthropathy associated with malformation and / or dysfunction of cartilage and / or subchondral bone. A kit is provided for performing transplantation into a joint or a cranio-facial-maxillary bone of a mammal of the composition of the invention.

The invention is an in-situ preparation method of nanometer zirconium and hydroxyapatite compound powder. The method comprises the following steps: ''in-situ''- zirconium oxychloride, calcium nitrite, diammonium hydrogen phosphate and ammonia water are used as the raw materials, which are put in a same reactor by proportion; the pH value of the reaction is controlled in an alkaline range; a precursor of the nanometer zirconium and hydroxyapatite compound powder is prepared through the stirring action of a mixer at a higher reaction temperature; then after- ''ultrasonic treatment''-'' ethanol rinsing''-''calcination''-''grinding'', the nanometer zirconium and hydroxyapatite compound powder is obtained. The positive effect of the invention is that the prepared compound powder provides a novel way for the modification of the nanometer particle biological material. The invention can be used to prepare high performance bioceramic, which is applied for the replacement of the artificial implants and artificial joints; the invention can forms the nanometer compound fillers with different particle size and component, which are used for the synthesis of high performance nanometer compound materials. The invention has a significant meaning in the application of the medical materials.

The invention relates to medical devices made from ternary single-phase ceramics. In an embodiment, the invention is a medical orthopedic implant comprising at least a portion made of a single-phase ceramic with a formula of Mn+1AXn (wherein n=1 to 3, M is an early transition metal, A is an A-group element, and X is C and / or N). In an embodiment, the invention is a method of treating a disorder associated with orthopedic malformation and / or dysfunction and wherein an implantation of artificial implant is needed, in a subject in need of such treatment, the method comprising implanting in said subject an implant having at least a portion thereof made of a single-phase ceramic with a formula of Mn+1AXn (wherein n=1 to 3, M is an early transition metal, A is an A-group element, and X is C and / or N.