Titanium/hydroxyl apatite biological composite material and preparation method thereof

A hydroxyapatite and composite material technology, applied in medical science, prosthesis, surgery, etc., can solve the problems of insufficient bone loading, stress shielding, mismatch of elastic modulus and mechanical properties, etc. The production process is simple and easy, and the effect of good biocompatibility

Inactive Publication Date: 2008-02-20
HARBIN INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to solve the common lack of osteoinductivity and osteoconductivity of the currently used artificial implants, the surface is not conducive to the growth and adhesion of bone cells, and the mismatch between the elastic modulus and mechanica

Method used

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Examples

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specific Embodiment approach 1

[0016] Specific embodiment 1: The titanium / hydroxyapatite biocomposite material in this embodiment is composed of titanium and hydroxyapatite, wherein the volume of titanium accounts for 60% to 75% of the total volume of the titanium / hydroxyapatite biocomposite material, The remainder is hydroxyapatite.

[0017] The preparation method of the titanium / hydroxyapatite biocomposite material of the present embodiment is:

[0018] Step 1: mixing titanium metal powder and hydroxyapatite powder into a mixed powder, 60% to 75% of the total volume of the mixed powder is titanium metal powder, and the rest is hydroxyapatite powder;

[0019] Step 2: Put the mixed powder obtained in Step 1 into a ball mill jar under an argon atmosphere, and ball mill it for 3 to 6 hours after sealing;

[0020] Step 3: Open the ball mill jar under an argon atmosphere, and take out the mixed powder after ball milling;

[0021] Step 4: Under an argon atmosphere, the ball-milled mixed powder obtained in Step...

specific Embodiment approach 2

[0029] Embodiment 2: The difference between this embodiment and the titanium / hydroxyapatite biocomposite material described in Embodiment 1 is that the particle diameter of the titanium metal powder is 20 μm to 80 μm, and the particle size of the hydroxyapatite powder is The diameter is 10 μm to 20 μm.

specific Embodiment approach 3

[0030] Embodiment 3: The difference between this embodiment and the titanium / hydroxyapatite biocomposite material described in Embodiment 1 is that the particle diameter of the titanium metal powder is 20 μm to 50 μm, and the particle size of the hydroxyapatite powder is The diameter is 10 μm to 15 μm.

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Abstract

The invention provides a titanium/hydroxyl apatite biological composite material and the preparing method thereof, relating to a biomaterial and the preparing technology thereof for the orthopaedics, which solves the problems that the present artificial implant is lack of bone inductivity and bone conductibility whose surface is not good for the bone cell growing and adhesion, and as the mismatching of the implant and the elastic modulus of the bone tissue with the mechanical property, the bone is not completely loaded, causing the stress shield and obstructing the growing and restitution of the bone tissue. The titanium/hydroxyl apatite biological composite material consists of the titanium and hydroxyl apatite, whose preparing method is as follows: mixing the titanium metal powder with the hydroxyl apatite powder, then filling into a agate jar and ball milling for 3 to 6 hours in the atmosphere of argon gas; after that, taking out and cold pressing to mold in the room temperature, sintering the cold press molding composite material with the plasma sintering technology; then, keeping the temperature for 0 to 30 minutes; finally, cooling down to the room temperature following the furnace. The titanium/hydroxyl apatite biological composite material is extensively applicable to the restoration of the bone tissue in medicine.

Description

Technical field: [0001] The invention relates to a biological material for orthopedics and a preparation process thereof. Background technique: [0002] Biomedical materials, also known as biomaterials, are materials for diagnosing, treating, and replacing damaged tissues and organs or improving their functions. [0003] The development and application of biological materials is of great significance to the protection of human health, the economic future of the country and the harmonious development of society. The research on biological materials has developed rapidly in the past 20 years, and has been included in the development plan of high-tech key new materials by many countries, and has quickly become one of the commanding heights of international high-tech. In the 1980s, developed countries such as Germany, the United States, Japan, the United Kingdom, Italy, and the Netherlands announced their own biomaterials research plans and invested heavily to attract talents, ...

Claims

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Application Information

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IPC IPC(8): A61L27/42A61L27/10A61L27/06A61L31/12
Inventor 刘志光张玉梅陈玉勇
Owner HARBIN INST OF TECH
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