Methods and systems for improving the reliability of orthogonally redundant glucose sensors
A technology of a sensor and a sensor device, applied in the field of sensors
Active Publication Date: 2016-10-12
MEDTRONIC MIMIMED INC
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Actions taken may vary from simply prompting the patient to calibrate the system, stopping the malfunctioning sensor and requiring a new sensor to be embedded
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[0092] In the following description, reference is made to the accompanying drawings, which form a part hereof and illustrate several embodiments of the invention. It is understood that other embodiments may be utilized and structural and operational modifications may be made without departing from the scope of the present invention.
[0093] The present invention is described below with reference to flowchart illustrations of methods, systems, apparatus, apparatus, and programming and computer program products. It can be understood that each module in the flowchart and combinations of modules in the flowchart can be implemented by programming instructions, including computer program instructions. These computer program instructions can be loaded onto a computer or other programmable data processing device (such as a controller, microcontroller, or processor on a sensor electronics device) to produce a machine so that the computer or other programmable The instructions execute...
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Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and / or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration. The electrochemical and optical SG values may be weighted (as a function of the respective sensor's overall reliability index (RI)) and the weighted SGs combined to obtain a single, fused SG value.
Description
[0001] relevant application data [0002] This application claims priority to the following patent application: US Provisional Application No. 61 / 916,632, filed December 16, 2013, which is incorporated by reference into this application. [0003] Technical Field of the Invention [0004] Embodiments of the invention generally relate to sensor technology, including sensors for detecting various physiological parameters, such as glucose concentration. More specifically, embodiments of the present invention relate to quadrature redundant glucose sensors and sensor systems, including closed loop insulin infusion systems, and to methods for improving the accuracy and reliability of quadrature redundant glucose sensors, devices, and systems. A precise calibration method and system and a sensor glucose (SG) fusion method and system. Background technique [0005] In response to elevated plasma glucose levels, the pancreas of a normal, healthy person produces and releases insulin ...
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IPC IPC(8): A61B5/145A61B5/1455A61B5/1459A61B5/1473
CPCA61B5/14532A61B5/14556A61B5/1459A61B5/1473A61B2560/0223A61B5/1468G01N33/49A61B5/1495A61B5/4839A61B5/7221A61B5/7278A61M5/14244A61M5/1723G01N27/4163A61M2005/1726A61M2230/201A61M2205/3306A61M2205/3592A61M2205/3584A61M2205/50A61M2205/505A61M2205/52A61B5/1455G01N21/00G01N33/66A61B5/14503A61B2560/0238A61B2562/06G01N21/84G01N27/27A61B5/0004A61M5/142A61M2230/005C12Q1/006G01N21/59G01N27/3274G01N2201/127
Inventor 安德烈亚·瓦尔萨乌斯基李小龙麦克·C·刘钟宇翔杨宁
Owner MEDTRONIC MIMIMED INC