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Application of Maqian essential oil in preparation of medicine for preventing and treating endometriosis

A technology for endometriosis and ectopic disease, applied in the field of medicine, to avoid adverse reactions and achieve the effect of obvious clinical advantages

Inactive Publication Date: 2016-10-26
XISHUANGBANNA TROPICAL BOTANICAL GARDEN CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, there are no literature reports on the use of anesthesia in the treatment of endometriosis

Method used

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  • Application of Maqian essential oil in preparation of medicine for preventing and treating endometriosis
  • Application of Maqian essential oil in preparation of medicine for preventing and treating endometriosis
  • Application of Maqian essential oil in preparation of medicine for preventing and treating endometriosis

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Embodiment

[0031] 1. Materials and methods

[0032] 1.1 Preparation of the essential oil of Maqian: Fresh Maqian fruit was collected from Mengwang Township, Xishuangbanna in November, and dried for later use. Soak the under-dried fruit of hemp in warm water (60°C, 120 minutes). It was then ultrasonically sonicated for 50 minutes, heated to boiling, and extracted for 2.5 hours. Extract with ether, and evaporate the ether to obtain essential oil of hemp.

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Abstract

The invention discloses application of Maqian essential oil in the preparation of a medicine for preventing and treating endometriosis. Primary cultured human ectopic endometrium stromal cell (ESC) is used as a model, and it is found through screening that Maqian essential oil has good activity of inhibiting endometriosis implantation and can inhibit TNF-alpha induced primary human ectopic endometrium stromal cell IL-8 secretion at low concentration (volume concentration is not lower than 0.001%) and inhibit human ectopic endometrium stromal cell proliferation and induce primary cultured human ectopic endometrium stromal cell apoptosis and necrosis at high concentration (volume concentration is not lower than 0.008%). Maqian essential oil as a Dai medicine component avoids many adverse reaction of Western medicine. The Maqian essential oil will not influence endocrine physiological function during medication and also will not influence normal reproduction requirement of female patients. The product has obvious clinic advantages.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to the application of anesthetia essential oil in the preparation of medicines for preventing and treating endometriosis. Background technique [0002] The health status of the endometrium is related to the physical, psychological and reproductive health of women, and has been paid more and more attention by clinical medical personnel. Among them, endometriosis is a common endometrial disease. [0003] Endometriosis ( figure 1 ), also known as extrauterine endometriosis, refers to the appearance of endometrial tissue outside the uterus. Endometriosis is a frequently-occurring disease in women of childbearing age, with an incidence rate of 3-6%. In recent years, the incidence rate has increased significantly. It mainly causes pain and infertility. The incidence rate of infertility is as high as 30-50%. Symptoms Disproportionate to the severity of signs and diseases, the lesions are ...

Claims

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Application Information

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IPC IPC(8): A61K36/758A61P15/00
CPCA61K36/758A61K2236/331A61K2236/39A61K2236/51A61K2236/53
Inventor 杨必成张萍黄欧平
Owner XISHUANGBANNA TROPICAL BOTANICAL GARDEN CHINESE ACAD OF SCI
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