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Compound medicine containing humifuse euphorbia herb and phosphonomycin for livestock

A technology of fosfomycin and dijincao, which is applied in the field of compound medicine for livestock and poultry, can solve the problems of high cost of medicine, serious infection, and failure to find out, and achieve the effect of low cost, obvious synergistic effect, and fast curative effect

Inactive Publication Date: 2016-11-16
GUANGXI UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0002] Livestock and poultry infected by Escherichia coli can cause acute sepsis, peritonitis, hepatitis, pneumonia, enteritis and many other serious infections, causing huge economic losses to livestock and poultry breeding
Fosfomycin, norfloxacin, florfenicol, etc. are commonly used western medicines to prevent and treat such diseases. With the increasing use of drugs, there are more and more drug-resistant strains, and the cost of drug use is also increasing. However, the treatment The effect and drug resistance have not improved, but worsened
[0003] After searching, there is no relevant report on the combination of Dijincao and fosfomycin for the treatment of livestock and poultry diseases caused by Escherichia coli infection

Method used

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  • Compound medicine containing humifuse euphorbia herb and phosphonomycin for livestock

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Experimental program
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Embodiment Construction

[0008] The technical solutions and beneficial effects of the present invention will be further described below in conjunction with specific examples. Unless otherwise stated, the weight of the sage grass in the present invention is the dry weight of the sage grass.

[0009] 1. Determination of the elimination effect of Dijincao on fosfomycin resistance

[0010] 1. Measurement method

[0011] According to the weight ratio of 1:1, 1:3, 1:5, 1:10, 1:30, 1:50, respectively prepare the mixed liquid of Dijincao and various western medicines; select the strains resistant to western medicines as the test Objects were subcultured by the plate dilution method, and the MIC changes of each treatment solution against drug-resistant strains were determined; at the same time, the western medicine without Dijincao was set as the positive control, and the Western medicine without Dijincao was set as the negative control.

[0012] The above treatments were continuously cultured for 4 generatio...

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Abstract

The invention relates to a compound medicine containing humifuse euphorbia herb and phosphonomycin for livestock. The compound medicine for the livestock is prepared from the phosphonomycin and the humifuse euphorbia herb, wherein the weight ratio of the phosphonomycin to the humifuse euphorbia herb is 1:10 to 1:30. The invention also requires protecting a compound preparation prepared by the compound medicine for the livestock. The compound medicine for the livestock provided by the invention has the beneficial effects that a experimental study proves that since the phosphonomycin and the humifuse euphorbia herb are jointly used according to a specific weight proportion, the compound medicine for the livestock has the advantages of remarkable synergistic effect, fast curative effect, low cost and the like.

Description

technical field [0001] The invention belongs to the technical field of compound medicines for livestock and poultry, and in particular relates to a compound medicine for livestock and poultry containing radix chinensis and fosfomycin, which is used for treating diseases caused by Escherichia coli infection in livestock and poultry. Background technique [0002] Livestock and poultry infected by Escherichia coli can cause acute sepsis, peritonitis, hepatitis, pneumonia, enteritis and many other serious infections, causing huge economic losses to livestock and poultry breeding. Fosfomycin, norfloxacin, florfenicol, etc. are commonly used western medicines to prevent and treat such diseases. With the increasing use of drugs, there are more and more drug-resistant strains, and the cost of drug use is also increasing. However, the treatment The effect and drug resistance situation have not been improved, but worsened. [0003] After searching, there is no relevant report on the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/47A61P31/04A61K31/665
CPCA61K31/665A61K36/47A61K2300/00
Inventor 不公告发明人
Owner GUANGXI UNIV
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