Application of Maqian essential oil in preparation of drug for preventing and treating adenomyosis
A technique for adenomyosis and essential oil, which is applied in the field of medicine to achieve the effect of avoiding adverse reactions
Inactive Publication Date: 2016-11-23
江西省妇幼保健院
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Problems solved by technology
At present, there are no literature reports on the use of anesthesia in the treatment of adenomyosis
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[0029] 1. Materials and methods
[0030] 1.1 Preparation of the essential oil of Maqian: Fresh Maqian fruit was collected from Mengwang Township, Xishuangbanna in November, and dried for later use. Soak the under-dried fruit of hemp in warm water (60°C, 120 minutes). It was then ultrasonically sonicated for 50 minutes, heated to boiling, and extracted for 2.5 hours. Extract with ether, and evaporate the ether to obtain essential oil of hemp.
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The invention discloses application of Maqian essential oil in preparation of a drug for preventing and treating adenomyosis. A primarily cultured human actopic endometrim stromal cell (ESC) is used as a model, through screening, the Maqian essential oil has good actopic endometrim planting inhibiting activity, when the concentration of the Maqian essential oil is low (the volume concentration is not lower than 0.01%o), secretion of TNF-alpha induced primary human actopic endometrim stromal cell IL-8 can be inhibited, when the concentration of the Maqian essential oil is high )the volume concentration is not lower than 0.08%o), proliferation of the human actopic endometrim stromal cell is inhibited, and apoptosis and necrosis of the primarily cultured human actopic endometrim stromal cell are induced. The Maqian essential oil is used as a Dai medicine ingredient, various adverse effects of western medicines are avoided, the internal secretion physiological function is not affected when a patient takes the drug, normal fertility demands of a female patient are not affected, and the clinic advantages are obvious.
Description
technical field [0001] The invention belongs to the technical field of medicine, and relates to the application of anesthetia essential oil in the preparation of medicines for preventing and treating adenomyosis. Background technique [0002] The health status of the endometrium is related to the physical, psychological and reproductive health of women, and has been paid more and more attention by clinical medical personnel. Among them, adenomyosis is a common endometrial disease. [0003] Adenomyosis, also known as intrauterine endometriosis, refers to the invasion of endometrial glands and / or stroma into the myometrium and diffuse growth in it. It is characterized by the appearance of ectopic endometrium and glands in the myometrium, with hypertrophy and hyperplasia of the surrounding myometrium. [0004] The pathogenesis of adenomyosis is unknown, but the widely accepted theory is that the endometrium grows directly downward from the basal layer into the myometrium. His...
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Login to View More IPC IPC(8): A61K36/758A61P15/00
CPCA61K36/758
Inventor 杨必成张萍黄欧平
Owner 江西省妇幼保健院
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