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Traditional Chinese medicinal composition for treating type-II diabetes and preparation method of traditional Chinese medicinal composition

A composition and diabetes technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of long effective time, many adverse reactions, and large dosage

Inactive Publication Date: 2016-11-23
陈红专
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, besides insulin, most of the drugs for clinical treatment of type II are chemical drugs. The widely used drugs can be roughly divided into sulfonylureas, biguanides, other hypoglycemic drugs and adjuvant drugs. However, these drugs have many adverse reactions and are safe to administer. bring hidden danger
In recent years, some traditional Chinese medicines for treating diabetes have appeared one after another, but most of them are taken in large doses and take a long time to take effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Take 8 parts of Rhodiola rosea, 10 parts of Eucommia ulmoides, 10 parts of Guanzhong, 12 parts of dendrobium, 8 parts of jujube seed, and 10 parts of Ligustrum lucidum. (V / V) ethanol, reflux extraction for 1 hour, filter, add 90% (V / V) ethanol 4 times its mass to the medicinal residue, reflux extraction for 1 hour, filter, combine the two extracts, recover ethanol and concentrate under reduced pressure (Temperature 50-80°C, vacuum degree 0.03MPa-0.09MPa) to a relative density of 1.25 (measured at 60°C) to obtain an extract, add appropriate amount of starch dextrin, granulate, then add magnesium stearate, mix and press into tablets.

Embodiment 2

[0026] Take 10 parts of Rhodiola rosea, 8 parts of Eucommia ulmoides, 8 parts of Guanzhong, 15 parts of Dendrobium, 12 parts of Jujube Seed, and 6 parts of Ligustrum lucidum. (V / V) ethanol, reflux extraction for 1 h, filter, add 30% (V / V) ethanol 6 times its mass to the dregs, reflux extraction for 0.5 h, filter, combine the two extracts, recover ethanol and decompress Concentrate (temperature 50-80°C, vacuum degree 0.03MPa-0.09MPa) to a relative density of 1.15 (measured at 60°C) to obtain an extract, which is crushed and packed into capsules after vacuum drying.

Embodiment 3

[0028] Take 6 parts of Rhodiola rosea, 12 parts of Eucommia ulmoides, 5 parts of Guanzhong, 8 parts of dendrobium, 10 parts of jujube seed, and 12 parts of Ligustrum lucidum. (V / V) ethanol, reflux extraction for 2 hours, filter, add 60% (V / V) ethanol 8 times its mass to the dregs, reflux extraction for 1 hour, filter, combine the two extracts, recover ethanol and concentrate under reduced pressure (Temperature 50-80°C, vacuum degree 0.03MPa-0.09MPa) to relative density 1.05 (measured at 60°C) to obtain extract, add appropriate pure water and auxiliary materials to prepare oral liquid according to conventional process.

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PUM

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating type-II diabetes. The traditional Chinese medicinal composition comprises, by weight, 6-12 parts of rhodiola rosea, 6-12 parts of eucommia ulmoides, 5-15 parts of cyrtomium fortune, 5-15 parts of dendrobium nobile, 6-12 parts of wild jujube seeds and 6-12 parts of glossy privet fruits. The invention further provides a preparation method of the traditional Chinese medicinal composition. According to the preparation method, vacuum concentration is performed after ethyl alcohol reflux extraction so as to achieve relative density of 1.05-1.25 (measured at the temperature of 60 DEG C), and extract is obtained. The traditional Chinese medicinal composition has remarkable clinical effect on the type-II diabetes, and the effective rate reaches above 93%.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating type II diabetes and a preparation method thereof. Background technique [0002] Diabetes mellitus is the most common endocrine and metabolic disease with genetic susceptibility and its onset triggered by environmental factors. With the development of society and economy, changes in people's lifestyles (increased energy intake and reduced exercise, etc.) and population aging, the incidence of type 2 diabetes is increasing year by year globally, especially in developing countries. Fast (expected to increase by 170% by 2025), presenting a trend of popularity. Diabetes has become the third non-communicable disease that threatens people's health and life after cardiovascular disease and tumors. [0003] At present, besides insulin, most of the drugs for clinical treatment of type II are chemical drugs. The widely used d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P3/10
CPCA61K36/11A61K36/41A61K36/46A61K36/638A61K36/725A61K36/8984A61K2236/15A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 陈红专
Owner 陈红专