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A kind of anti-moisture absorption fucoidan product and preparation method thereof

A fucoidan, anti-absorption technology, applied in pharmaceutical formulations, food coating, medical preparations with non-active ingredients, etc. Not good and other problems, to avoid moisture absorption, increase content, reduce the effect of single use

Active Publication Date: 2019-08-20
QINGDAO BRIGHT MOON SEAWEED GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Fucoidan is a kind of macromolecular mucopolysaccharide, which is easy to absorb moisture and deteriorate in the air. At present, in order to prevent the moisture absorption of fucoidan, it is mostly made into granules, tablets, solid drinks and other product forms. However, these products The form requires the addition of a large amount of excipient ingredients (30-60%), resulting in a reduction in the content of fucoidan
In order to achieve the effect of use, people have to eat a large number of products each time, which has a very bad impact on factory production and consumer experience.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0026] As mentioned above, the preparation method of the anti-moisture absorption fucoidan product comprises the following steps:

[0027] 1) Weigh the basic raw materials fucoidan, sugar powder and emulsifier in proportion and mix them evenly, then add them into the pellet machine; the mixing method can be one of three-dimensional mixing, cone mixing or groove mixing, because different The mixing uniformity of the mixing method is different, and the time required for mixing is different. For example, it takes 15-25 minutes for conical mixing, 25-35 minutes for three-dimensional mixing, and 35-45 minutes for trough mixing.

[0028] 2) Weigh the ingredients of the adhesive powdered sugar, emulsifier and water in proportion, mix them evenly, and spray them into the mixed basic raw materials in the form of mist, the spraying speed is 15-25mL / min, and the basic raw materials are in the rolling process Forming pellets, each pelleting time is 25-35min; the above-mentioned spraying s...

Embodiment 1

[0034] Prepare the anti-moisture absorption fucoidan pellet preparation as follows:

[0035] 1) The white granulated sugar is crushed and passed through an 80-mesh sieve to obtain powdered sugar. Accurately weigh 800g of fucoidan, 120g of powdered sugar, and 80g of Tween-80, and mix them in a conical shape for 20 minutes until they are evenly mixed;

[0036] 2) Pour the basic raw materials mixed in step 1) into the pellet machine, and spray the spray adhesive to prepare pills; the adhesive is 8 parts by mass of Tween-80 and 40 parts by mass of powdered sugar Dissolved in 100 parts by volume of solvent water; the spray rate of the adhesive in the pelletizing machine is 20mL / min, the state is misty, and the pelleting time is about 30min each time;

[0037]3) The above-mentioned pills are sieved, first sieved with a 12-mesh sieve, and the passed pills are put back into the pill-making machine to continue making pills. The failed pills are collected and sieved with a 10-mesh sieve...

Embodiment 2

[0041] Prepare the anti-moisture absorption fucoidan pellet preparation as follows:

[0042] 1) The white granulated sugar is crushed and passed through an 80-mesh sieve to obtain powdered sugar. Accurately weigh 85kg of fucoidan, 10kg of powdered sugar, and 5kg of Tween-80, and mix them in a tank for 40 minutes until they are evenly mixed;

[0043] 2) Pour the basic raw materials mixed in step 1) into the pellet machine, and spray the spray adhesive to prepare pills; the adhesive is 5 parts by mass of Tween-80 and 30 parts by mass of powdered sugar Dissolved in 100 parts by volume of solvent water; the spray rate of the adhesive in the pelletizing machine is 20mL / min, the state is misty, and the pelleting time is about 30min each time;

[0044] 3) The above-mentioned pills are sieved, first sieved with a 12-mesh sieve, and the passed pills are put back into the pill-making machine to continue making pills. The failed pills are collected and sieved with a 10-mesh sieve, and th...

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Abstract

The invention discloses a moisture-absorbing fucoidan product and a preparation method thereof. The product includes internal pills and an outer coating agent. The internal pills include basic raw materials and adhesives. The components of the basic raw materials are rock. 80-85 parts by mass of algae polysaccharide, 8-12 parts by mass of sugar powder and 5-8 parts by mass of emulsifier; the components of the adhesive are 30-40 parts by mass of sugar powder, 5-8 parts by mass of emulsifier, and water 100 parts by volume. The pellets of the present invention solve the contradiction between fucoidan product content and moisture absorption. The produced product has high fucoidan content, is not easy to absorb moisture, and is convenient for consumption.

Description

technical field [0001] The invention belongs to the technical field of seaweed chemical industry, and in particular relates to a fucoidan product and a preparation method thereof. Background technique [0002] Fucoidan (FUC) is a class of polysaccharides mainly composed of fucose and sulfate ester groups. It is widely found in brown algae and some marine invertebrates (such as sea cucumbers, sea urchins, etc.) Physiological activities, such as anticoagulant and antithrombotic, antiviral, antitumor, immune regulation, anti-inflammatory, hypolipidemic, antioxidative, anti-complement properties, gastric protection, etc., in recent years, for the purpose of drug and health food development There are more and more studies on FUC. [0003] Fucoidan is a kind of macromolecular mucopolysaccharide, which is easy to absorb moisture and deteriorate in the air. At present, in order to prevent the moisture absorption of fucoidan, it is mostly made into granules, tablets, solid drinks an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/50A61K31/737A61K47/26A61K47/38A61P7/02A61P31/12A61P35/00A61P37/02A61P29/00A61P3/06A61P39/06A61P1/00A23L33/125A23P20/18
Inventor 王春霞王晓梅李可昌范素琴王正平
Owner QINGDAO BRIGHT MOON SEAWEED GROUP
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