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Protective cap for prefilled syringe, preparation method and structure of rubber protective cap

A syringe and pre-filling technology, which is applied in the direction of hypodermic injection devices, devices introduced into the body, needles, etc., can solve the problems of cap popping, poor sealing performance, and leakage, so as to reduce the risk of leakage and reduce the risk of leakage. Risk of liquid leakage, effect of increasing the sealing area

Active Publication Date: 2018-07-10
SHANDONG PHARMA GLASS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the prefilled syringes in the market do not have needles. In the process of filling, especially when customers need centrifugal exhaust, due to poor sealing performance, liquid leakage and air leakage are caused, resulting in contamination and deterioration of filled drugs.
At present, during the filling and sterilization process of prefilled syringes with needles in the market, there is a problem that the protective cap pops up or even falls off, which leads to poor sealing and contamination and deterioration of the filled drug.

Method used

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  • Protective cap for prefilled syringe, preparation method and structure of rubber protective cap
  • Protective cap for prefilled syringe, preparation method and structure of rubber protective cap
  • Protective cap for prefilled syringe, preparation method and structure of rubber protective cap

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The present invention is a protective cap for prefilled syringes. The raw materials are calculated in parts by weight, and the raw materials are composed as follows:

[0029]

[0030]

[0031] Stearic acid is stearic acid; accelerator DPTT is bispentamethylene thiuram tetrasulfide; rubber additive is sulfur; antioxidant is β-3,5-di-tert-butyl-4-hydroxyphenyl Octadecyl Propionate.

[0032] The preparation method of the protective cap for prefilled syringes is characterized in that the steps are as follows: raw material blending, kneading, kneading, cooling and storage, extrusion, calendering, cooling and storage, forming, edge removal, and sieving Pre-washing, cleaning, inner packaging, outer packaging, storage.

[0033] Kaolin is calcined before use.

[0034] The structure of the protective cap for pre-filling syringes includes a protective cap body 1, a cavity is arranged inside the protective cap body 1, the top of the cavity is a needle point matching cavity ...

Embodiment 2

[0037] The present embodiment is the same as Example 1, the difference is that the raw material mass fraction is as follows:

[0038]

[0039]

Embodiment 3

[0041] This embodiment is the same as Example 1, except that the mass parts of raw materials are as follows:

[0042]

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PUM

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Abstract

The invention relates to a protection cap for a pre-potting injector, a preparation method and a structure of a rubber protection cap. The protection cap is prepared from the following raw materials in parts by weight: 100 parts of polyisoprene rubber, 0.3 to 0.5 part of stearic acid, 0.4 to 0.6 part of a promoting agent DPTT, 2.5 to 3 parts of a rubber auxiliary, 1.0 to 1.5 parts of an antioxidant, 80 to 100 parts of kaoline, 5 to 10 parts of white carbon black, 2 to 4 parts of polyethylene wax, 3 to 5 parts of titanium dioxide and 0.1 to 0.5 part of carbon black. According to the protection cap for the pre-potting injector, the preparation method and the structure of the rubber protection cap, the risk of liquid leakage of the pre-potting injector is greatly reduced, and reduction of the sealing property due to popping up, caused by the fact that gas sealed in an inner cavity of the original structure is swelled under a condition that the external air pressure is reduced, of the protection cap is avoided. The protection cap enlarges the sealing area, reduces the risk of liquid leakage and reduces the requirement on cooperation of the original structure. The structure effectively reduces the risks of liquid leakage and gas leakage.

Description

technical field [0001] The invention relates to a protective cap for a prefilled syringe, a preparation method and the structure of the rubber protective cap. Background technique [0002] Pre-filled syringes are a new form of pharmaceutical packaging developed in the 1990s abroad. Now they are more and more used in the packaging of high-end drugs. They have both functions of storing drugs and ordinary injections. Currently, pre-filled syringes without needles in the market are filled, especially when customers need centrifugal exhaust, due to poor sealing performance, resulting in liquid and air leakage, which leads to contamination and deterioration of filled medicines. At present, during the filling and sterilization process of prefilled syringes with needles in the market, there is a problem that the protective cap pops up or even falls off, which leads to poor sealing and contamination and deterioration of the filled medicine. Our company redesigns and optimizes the st...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L9/00C08L23/06C08K13/06C08K5/09C08K3/34C08K3/36C08K3/04A61M5/32
CPCA61M5/3202C08L9/00C08L23/06C08K13/06C08K5/09C08K3/346C08K3/36C08K3/04
Inventor 孟凡平杜彬逯纪伟
Owner SHANDONG PHARMA GLASS