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Nutrition compound and application in preparing drug for promoting stem cell proliferation

A nutritional composition and stem cell proliferation technology, which is applied in the direction of drug combination, effective ingredients of hydroxyl compounds, pharmaceutical formulations, etc., can solve the problem of not being able to meet the needs of stem cell proliferation

Inactive Publication Date: 2017-01-25
吴文国 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

That is, the nutritional composition can only promote the proliferation of hematopoietic stem cells and liver stem cells, and cannot meet the needs of other stem cell proliferation

Method used

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  • Nutrition compound and application in preparing drug for promoting stem cell proliferation
  • Nutrition compound and application in preparing drug for promoting stem cell proliferation
  • Nutrition compound and application in preparing drug for promoting stem cell proliferation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Example 1: The mass (mg) ratio of each component of the nutritional composition of the present invention is as follows: lysine 200-1200, methionine 100-1600, phenylalanine 150-1400, threonine 50-600, Tryptophan 50~400, Arginine 200~1500, Histidine 100~1000, Glycine 100~600, Aspartic Acid 100~600, Leucine 100~600, Isoleucine 100~600, Valine Amino acid 100~800, Serine 100~400, Glutamine 200~600, Taurine 100~500, Orotic acid 100~300, Nucleotide 200~1200, Vitamin A 0.2~0.6, Vitamin D 0.002~0.006 , Vitamin B 2 1~4, vitamin B 6 1~4, vitamin B 12 0.001~0.006, niacin 5~20, folic acid 0.01~1.2, vitamin C 50~150, iron 2~10, zinc 2~10, manganese 2~10, copper 0.5~2, selenium 0.01~0.1, chromium 0.01~0.02 , potassium 10~300, calcium 100~300, magnesium 100~200, inositol 50~60, soybean lecithin 100~2500.

Embodiment 2

[0025] Example 2: The mass (mg) ratio of each component is as follows: lysine 600, methionine 800, phenylalanine 700, threonine 300, tryptophan 200, arginine 760, histidine 500 , Glycine 300, Aspartic Acid 300, Leucine 300, Isoleucine 300, Valine 400, Serine 200, Glutamine 300, Taurine 500, Orotic Acid 300, Nucleotide 400, Vitamin A0.6, vitamin D0.006, vitamin B 2 2. Vitamin B 6 2. Vitamin B 12 0.004, niacin 12, folic acid 0.9, vitamin C100, iron 10, zinc 10, manganese 8, copper 2, selenium 0.1, chromium 0.02, potassium 300, calcium 300, magnesium 200, inositol 60, soybean lecithin 1200.

[0026] The nutritional composition has the effect of promoting the proliferation of hematopoietic stem cells, liver stem cells, mesenchymal stem cells, kidney stem cells and gastric mucosal stem cells, and can be applied to the preparation of drugs for promoting stem cell proliferation.

[0027] Embodiment 1,2 raw material sources are as follows:

[0028]

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PUM

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Abstract

The invention discloses a nutrition compound and application in preparing a drug for promoting stem cell proliferation. The nutrition compound is prepared from the following materials in proportion: lysine, methionine, phenylalanine, threonine, tryptophan, arginine, histidine, glycine, aspartic acid, leucine, isoleucine, valine, serine, glutamine, taurine, orotic acid, nucleotide, Vitamin A, Vitamin D, Vitamin B2, Vitamin B6, Vitamin B12, niacin, folic acid, Vitamin C, iron, zinc, manganese, copper, selenium, chromium, potassium, calcium, magnesium, inositol and granulesten. The nutrition compound has the effects of boosting the proliferation of hematopoietic stem cells, liver stem cells, mesenchymal stem cells, kidney stem cells and gastric mucosa stem cells. The nutrition compound can be used for preparing the drug for promoting stem cell proliferation, is free from toxic and side effect and can avoid various problems caused by introduction of exogenous stem cells for treating diseases.

Description

technical field [0001] The present invention relates to a nutritional composition and its application, in particular to a nutritional composition capable of promoting the proliferation of five stem cells including hematopoietic stem cells and mesenchymal stem cells, and its application in the preparation of stem cell proliferation medicines. Background technique [0002] With the continuous development of stem cell biology research, transplantation therapy using stem cells as seed cells will bring new hope to patients. However, without any improvement in the macro and micro environment of the body, its original corresponding stem cells are still in a "dormant" state, and it is obviously difficult to achieve the desired goal only by relying on foreign stem cell delivery. At the same time, there are still many key issues to be solved in order to turn stem cells into drugs, for example, how to maintain the differentiation ability, genetic characteristics, tumorigenicity and sta...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/34A61P43/00A61K31/047A61K31/07A61K31/185A61K31/195A61K31/198A61K31/375A61K31/405A61K31/4172A61K31/4415A61K31/455A61K31/513A61K31/519A61K31/525A61K31/59A61K31/7052A61K31/714A61K33/00A61K33/04A61K33/06A61K33/24A61K33/26A61K33/30A61K33/32
CPCA61K31/405A61K31/047A61K31/07A61K31/185A61K31/195A61K31/198A61K31/375A61K31/4172A61K31/4415A61K31/455A61K31/513A61K31/519A61K31/525A61K31/59A61K31/7052A61K31/714A61K33/00A61K33/04A61K33/06A61K33/24A61K33/26A61K33/30A61K33/32A61K33/34A61K2300/00
Inventor 吴文国贾莉杨佩满
Owner 吴文国
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