Cerenkov radiation imaging method and system

Abstract

The invention provides a cerenkov radiation imaging method. The cerenkov radiation imaging method comprises the following steps: injecting isotopes capable of emitting charged particles; reading the count of cerenkov photons emitted by the charged particles and transmitted to a detector module and the time for each photon count; carrying out time coincidence on the read cerenkov photons; estimating the occurring position of the cerenkov event according to the relative location of the photons in holes; and carrying out judgment and selection according to the energy and angle widening of the plurality of photons, and after triggering, acquiring other interesting information such as angle and momentum from the electric pulse set of the cerenkov event. The invention further provides a cerenkov radiation imaging system. The cerenkov radiation imaging system comprises an isotope injection module, a photoelectric detector module, a multi-case time coincidence module, a cerenkov event estimation module and a nuclide distribution image reconstruction module. With the adoption of the cerenkov radiation imaging method and the cerenkov radiation imaging system provided by the invention, the spatial resolution and imaging signal-to-noise ratio of the system can be effectively improved, and the cerenkov radiation imaging method is particularly suitable for being applied in in-vivo small animal imaging and superficial clinical diagnosis.

Description

technical field [0001] The invention relates to the fields of digital signal processing, photoelectric signal processing and nuclear detection, in particular to a single-photon time-resolved Cerenkov radiation imaging method and system. Background technique [0002] Cerenkov radiation detection is an optical imaging method that emits photons of visible and near-infrared light by the Cherenkov effect. Radioactive isotopes with Cerenkov radiation can be used as probes for in vivo imaging. By participating in various physiological and biochemical processes of organisms, they can constitute a new imaging method. In optical imaging and multimodal medical imaging It has wide application value. In 2010, Alessandro Ruggiero et al. (J. Nucl. Med.2010,51:1123-1130) in the United States confirmed that high-speed charged particles emitted by radioactive isotopes with α or β decay can emit Cerenkov in the medium by using a single-view lens. radiation, and the radiated photons have a ce...

AI Technical Summary

Problems solved by technology

A high-density scintillator is required to convert high-energy photons into visible light photons, so it has a high cost

[0004] However, due to the lens design of the existing Cherenkov imaging system, its detection efficiency is low, the imaging time is long, and the sensitivity is not as good as that of the existing PET imaging system.

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