No-sucrose compound lonicera granule and preparation method thereof

A compound honeysuckle and sucrose-free technology, applied in the field of compound honeysuckle granules and their preparation, can solve the problems of inducing diabetes and children's dental caries, sugar-containing granules are easy to deliquescence, and the dosage of auxiliary materials is large, so as to reduce the dosage of auxiliary materials and improve the medicine. Stability, effect of simple preparation method

Inactive Publication Date: 2017-05-10
GUANGXI DOUBLE ANT PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The compound honeysuckle granules in the prior art are sucrose-containing granules, which have the following disadvantages: (1) the sugar-containing granules are easy to deliquescence, soften and deteriorate, and are not suitable for long-term storage; Generally, it is 10g / bag, and the dosage of excipients is large; (3) Because sucrose has strong biological activity, it can cause gastritis, obesity, diabetes and dental caries in children, so the granules are not suitable for diabetes and other sugar-free patients

Method used

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  • No-sucrose compound lonicera granule and preparation method thereof

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Effect test

Embodiment 1

[0029] The sucrose-free compound honeysuckle granules in this example are made of the following raw materials: 450 kg of honeysuckle, 550 kg of forsythia, 150 kg of Scutellaria baicalensis, 4 kg of aspartame and 4 kg of dextrin.

[0030] The preparation method of the above-mentioned sucrose-free compound honeysuckle granule comprises the following steps:

[0031] (1) Preparation of honeysuckle extract: Weigh 450 kg of honeysuckle, add 2.5 times the weight of honeysuckle, soak in water for 25 minutes, heat and decoct to keep a slight boil, collect the distillate of 0.02 times the weight of honeysuckle, filter, and collect the filtrate once; add filter residue Heat and decoct 2.5 times the weight of water, keep boiling slightly for 25 minutes, filter, collect the secondary filtrate, combine the primary filtrate and the secondary filtrate to obtain the combined filtrate; concentrate the combined filtrate under reduced pressure to obtain honeysuckle clear paste; extract the honeysu...

Embodiment 2

[0035] The sucrose-free compound honeysuckle granules of this example are made of the following raw materials: 500 kg of honeysuckle, 500 kg of forsythia, 166.7 kg of scutellaria baicalensis, 3 kg of aspartame and 5 kg of dextrin.

[0036] The preparation method of the above-mentioned sucrose-free compound honeysuckle granule comprises the following steps:

[0037] (1) Preparation of honeysuckle extract: Weigh 500 kg of honeysuckle, add 3 times the weight of honeysuckle, soak in water for 30 minutes, heat and decoct to keep a slight boil, collect the distillate of 0.02 times the weight of honeysuckle, filter, and collect the filtrate once; add filter residue Heat and decoct 3 times the weight of water, keep boiling slightly for 30 minutes, filter, collect the secondary filtrate, combine the primary filtrate and the secondary filtrate to obtain the combined filtrate; concentrate the combined filtrate under reduced pressure to obtain honeysuckle clear paste; extract the honeysuck...

Embodiment 3

[0041] The sucrose-free compound honeysuckle granules of this example are made of the following raw materials: 550 kg of honeysuckle, 450 kg of forsythia, 180 kg of scutellaria baicalensis, 2 kg of aspartame and 6 kg of dextrin.

[0042] The preparation method of the above-mentioned sucrose-free compound honeysuckle granule comprises the following steps:

[0043] (1) Preparation of honeysuckle extract: Weigh 550 kg of honeysuckle, add 3.5 times the weight of honeysuckle, soak in water for 35 minutes, heat and decoct to keep a slight boil, collect the distillate of 0.02 times the weight of honeysuckle, filter, and collect the filtrate once; add filter residue Heat and decoct 3.5 times the weight of water, keep boiling slightly for 35 minutes, filter, collect the secondary filtrate, combine the primary filtrate and the secondary filtrate to obtain the combined filtrate; concentrate the combined filtrate under reduced pressure to obtain honeysuckle clear paste; extract the honeysu...

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Abstract

The invention discloses a no-sucrose compound lonicera granule and a preparation method thereof which belong to the technical field of traditional Chinese medicines. The no-sucrose compound lonicera granule is prepared from the following raw materials in parts by weight: 450-550 parts of lonicera japonica, 450-550 parts of fructus forsythiae, 150-180 parts of scutellaria baicalensis, 2-4 parts of aspartame and 4-6 parts of dextrin. The invention also provides the preparation method of the no-sucrose compound lonicera granule. The no-sucrose compound lonicera granule disclosed by the invention has the following advantages that: (1) the stability of the drug is improved; (2) the dosage of adjuvant materials is decreased; (3) the application scope is enlarged. Additionally, the preparation method disclosed by the invention is simple, the production cost of the no-sucrose compound lonicera granule is lower than that of a sucrose compound lonicera granule, the yield is high, the adjuvant materials are cheap and easy to obtain, the property is stable, the market prospect is broad, and the no-sucrose compound lonicera granule is suitable for large-scale volume production.

Description

technical field [0001] The invention relates to a sucrose-free compound honeysuckle granule and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. Background technique [0002] Compound honeysuckle granules are made of three traditional Chinese medicines: honeysuckle, forsythia, and baicalin. It has the effects of clearing heat and detoxifying, cooling blood and reducing swelling. disease. The efficacy of the compound traditional Chinese medicine is the result of the joint action of multiple components. In order to better improve the stability of the drug, expand the scope of application, and improve product quality, necessary improvements have been made to the preparation process and prescription of compound honeysuckle granules. [0003] The compound honeysuckle granules in the prior art are sucrose-containing granules, which have the following disadvantages: (1) the sugar-containing granules are easy to deliquescence, soften ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K47/36A61K47/18A61K36/634A61P11/00A61P11/04A61P27/02A61P29/00A61P1/02A61P17/02
CPCA61K9/1652A61K9/1617A61K36/355A61K36/539A61K36/634A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 曾秋菊王波
Owner GUANGXI DOUBLE ANT PHARMA
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