Cold storage gel, preparation method thereof and cold application patch
A technology of cold gel and konjac gum powder is applied in the field of medical supplies, which can solve the problems of inconvenient wearing, poor gel fit, and no antibacterial barrier.
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Embodiment 1
[0025] (1) Preparation of solution A: 0.3% by weight of menthol, 0.5% of vitamin E, 19% of glycerin, and 0.4% of apple extract were added to ethanol with a weight percentage of 4% as a solvent;
[0026] (2) Prepare solution B: add 0.8% hemicellulose and 0.2% konjac gum powder to 74.7% by weight purified water, and dissolve at 50°C until completely dissolved;
[0027] (3) Prepare solution C: accurately weigh 100g of potato starch and 3g of sodium trimetaphosphate in a test tube, add 400ml of purified water, and slowly add a 10% NaOH solution dropwise while stirring at 40 degrees Celsius. Keep the reaction pH value at 11, and keep it warm for 3 hours to obtain a cross-linked potato starch solution;
[0028] (4) Stir the 0.1% by weight solution C with the above solutions A and B at 40°C to form a gel.
Embodiment 2
[0030] (1) Preparation of solution A: 0.3% by weight of menthol, 0.5% of vitamin E, 19% of glycerin, and 0.4% of apple extract were added to ethanol with a weight percentage of 4% as a solvent;
[0031] (2) Preparation of solution B: Add 0.8% hemicellulose and 0.2% konjac gum powder to 74.3% by weight purified water, until completely dissolved at 50°C;
[0032] (3) Prepare solution C: accurately weigh 100g of potato starch and 3g of sodium trimetaphosphate in a test tube, add 400ml of purified water, and slowly add a 10% NaOH solution dropwise while stirring at 40 degrees Celsius. Keep the reaction pH value at 11, and keep it warm for 3 hours to obtain a cross-linked potato starch solution;
[0033] (4) Stir the 0.5% by weight solution C with the above solutions A and B at 40°C to form a gel.
Embodiment 3
[0035] (1) Preparation of solution A: 0.3% by weight of menthol, 0.5% of vitamin E, 19% of glycerin, and 0.4% of apple extract were added to ethanol with a weight percentage of 4% as a solvent;
[0036] (2) Preparation of solution B: Add 0.8% hemicellulose and 0.2% konjac gum powder to 72.8% by weight purified water, until completely dissolved at 50°C;
[0037] (3) Prepare solution C: accurately weigh 100g of potato starch and 3g of sodium trimetaphosphate in a test tube, add 400ml of purified water, and slowly add a 10% NaOH solution dropwise while stirring at 40 degrees Celsius. Keep the reaction pH value at 11, and keep it warm for 3 hours to obtain a cross-linked potato starch solution;
[0038] (4) Stir the 2% by weight solution C with the above solutions A and B at 40°C to form a gel.
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