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Preparation and application of total active materials of ganoderma lipsiense

A technology of ganoderma lucidum and active substances, which is applied in the field of preparation and application of active substances of ganoderma lucidum, can solve the problems of incomplete preparation of active substances and low utilization rate, and achieve the improvement of human immunity, high repeatability, resistance The effect of cardiovascular and cerebrovascular diseases

Inactive Publication Date: 2017-06-30
FUJIAN AGRI & FORESTRY UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide a kind of preparation and application of the active substance of Ganoderma lucidum, which can solve the existing problems of incomplete preparation of active substances and low utilization rate, and has a good effect on promoting the large-scale industrial production of Ganoderma lucidum products. Application prospects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] 1) Grind the fruiting body of Ganoderma lucidum into fine powder with a pulverizer;

[0022] 2) According to the ratio of material to liquid 1:50 kg / L, the obtained Ganoderma lucidum fine powder was used as a solvent with 85wt% ethanol solution, ultrasonic-microwave co-extracted at 70°C for 0.5h, and filtered to obtain 85% ethanol extract of Ganoderma lucidum ;

[0023] 3) According to the material-liquid ratio of 1:50 kg / L, use 55wt% ethanol solution as the solvent to extract the remaining filter residue from step 2) at 70°C for 0.5h with ultrasonic-microwave co-extraction, and filter to obtain 55% ethanol extract of Ganoderma lucidum ;

[0024] 4) According to the ratio of material to liquid 1:50 kg / L, use deionized water as a solvent to extract the remaining filter residue from step 3) at 100°C for 0.5h by ultrasonic-microwave co-extraction, and filter to obtain the aqueous extract of Ganoderma lucidum;

[0025] 5) Finally, the residue from step 4) was hydrolyzed w...

Embodiment 2

[0029] 1) Grind the fruiting body of Ganoderma lucidum into fine powder with a pulverizer;

[0030] 2) According to the solid-liquid ratio of 1:30 kg / L, the obtained fine powder of Ganoderma lucidum was used as solvent with 90wt% ethanol solution, ultrasonic-microwave co-extracted at 60°C for 1 hour, and filtered to obtain 90% ethanol extract of Ganoderma lucidum;

[0031] 3) According to the solid-liquid ratio of 1:30 kg / L, use 60wt% ethanol solution as a solvent to extract the remaining filter residue from step 2) at 50°C for 1 hour with ultrasonic-microwave co-extraction, and filter to obtain 60% ethanol extract of Ganoderma lucidum;

[0032] 4) According to the ratio of material to liquid 1:30 kg / L, use deionized water as the solvent for the remaining filter residue in step 3), ultrasonically assist extraction at 70°C for 3 hours, and filter to obtain the aqueous extract of Ganoderma lucidum;

[0033] 5) Finally, the residue from step 4) was hydrolyzed with complex proteas...

Embodiment 3

[0037] 1) Grind the fruiting body of Ganoderma lucidum into fine powder with a pulverizer;

[0038] 2) According to the solid-liquid ratio of 1:10 kg / L, the obtained Ganoderma lucidum powder was extracted with 95wt% ethanol solution as a solvent, ultrasonically assisted extraction at 45°C for 3 hours, and filtered to obtain 95% ethanol extract of Ganoderma lucidum;

[0039] 3) Use 65wt% ethanol solution as the solvent for the remaining filter residue in step 2) according to the ratio of solid to liquid: 1:10 kg / L, ultrasonically assist extraction at 45°C for 3 hours, and filter to obtain 65% ethanol extract of Ganoderma lucidum;

[0040] 4) Mix the obtained Ganoderma lucidum 95% ethanol extract, Ganoderma lucidum 65% ethanol extract, lily flower water extract, wolfberry water extract at a weight ratio of 1:2:1:0.5, dry and fill capsules, Ganoderma ganoderma health-care capsules were prepared.

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PUM

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Abstract

The invention discloses preparation and application of total active materials of ganoderma lipsiense. According to the total active materials, the ganoderma lipsiense is taken as a raw material, after the ganoderma lipsiense is smashed, an ethanol solution and water, the polarity of which is from small to large, are adopted to perform step-by-step extraction, compound protease is used for enzymolysis, 85 to 95% of an alcohol extract of the ganoderma lipsiense and 55 to 65% of an alcohol extract of the ganoderma lipsiense, a water extract of the ganoderma lipsiense and zymolyte are respectively obtained, namely the total active materials of the ganoderma lipsiense are obtained. According to the theory of emperor, minister, adjuvant and courier in traditional Chinese medicine and the theory of modern nutriology, one or a plurality of kinds of total active materials of the ganoderma lipsiense and other affinal drug and diet active ingredients having the same efficacy are compounded so as to prepare nutritional functional foods which have the effects of boosting immunity, regulating blood sugar, blood fat and blood pressure, protecting a liver and the like.

Description

technical field [0001] The invention belongs to the technical field of separation of natural active ingredients, and in particular relates to the preparation and application of a whole active substance of Ganoderma lucidum. Background technique [0002] Ganoderma lucidum is a kind of fungus with both food and medicine. In terms of fungal classification, it belongs to Basidiomycetes, Phytomycetes, Non-Armycetes, Ganodermaceae, and Ganoderma genus. Ganoderma lucidum is rich in a variety of nutrients, such as polysaccharides, steroids, triterpenes, lipids, amino acids, polypeptides, proteins, alkaloids, phenols, lactones, coumarins and glycosides, and trace elements etc., the prepared not only has the unique flavor of Ganoderma lucidum, but also has the function of enhancing human immunity. Eliminate fatigue. Protect the liver and protect the liver. Inhibit the growth of cancer cells, improve sleep quality, detoxify the intestines, beautify, nourish and strengthen the body, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L31/00A23L33/00
Inventor 刘斌花朋朋贾瑞博潘雨阳李田田郭伟灵陈弘培赵立娜陈珍金江小琴
Owner FUJIAN AGRI & FORESTRY UNIV