Porous composite bone plate with stiffness and gradient variation and preparation method thereof

Abstract

The invention provides a porous composite bone plate with stiffness and gradient variation and a preparation method thereof. The bone plate is formed by sequentially connecting a bonding layer, a transition layer and a physical layer, wherein the bonding layer, transition layer and physical layer are successively increased in stiffness. The corresponding position of the layers is provided with a positioning hole in a penetrating mode. The bonding layer with smaller stiffness is in contact with the original bone, therefore the stiffness of the contact surface of the bone plate can be reduced and the stress shielding effect is improved; the physical layer with larger stiffness achieves the fixed connection; a porous structure is arranged on the bonding layer and the transition layer respectively, thereby promoting the adhesion growth of cells, forming the more solid biological fixation, and being conducive to the long-term effective service of the bone plate. The bone plate overall structure uses 3D printing to be molded integrally, thus the natural transition and convergence from the porous structure of the bonding layer and transition layer to the physical structure of the physical layer can be achieved; the bone plate possesses obvious heterogeneous mechanical properties. According to the porous composite bone plate with the stiffness and gradient variation and the preparation method thereof, an individualized composite bone plate with stiffness and gradient variation and multi-directional gradient structures can be designed for different parts according to the individual difference, thereby improving the adaptability and biocompatibility of the bone plate.

Description

technical field [0001] The invention relates to a porous composite bone plate with varying stiffness gradients and a preparation method thereof, belonging to the technical field of biomedical prostheses. Background technique [0002] With the occurrence of traffic accidents, natural disasters and the deepening of the aging society, the demand for bone repair and bone replacement is increasing. How to provide safe and reliable bone implants with good mechanical properties has become an urgent clinical problem to be solved. one. Among them, bone plate, also known as "orthopedic plate", is the most commonly used human bone implant, which is in great demand in actual clinical practice and plays a pivotal role. [0003] Traditional bone plates are mostly mass-produced, differ only in model and size, and are mostly made of metal entities. The stiffness and strength of the existing biomedical metals are much greater than those of human bones, which can easily cause the mechanical...

AI Technical Summary

Problems solved by technology

At present, there are related products that reduce the weight of the bone plate by partially opening holes, such as skull prostheses, but this is still a structural optimization at the macro level, and cannot further improve the stiffness of the solid bone plate. For prostheses and Problems such as stress shielding of human original bones have not been well resolved

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