Device and method for hemorrhage detection and guided resuscitation and applications of same
A technology for monitoring devices and blood vessels, applied in applications, special data processing applications, catheters, etc., can solve problems such as harsh environments, ineffective monitoring devices, and lack of remote monitoring
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[0108] In one example, offers include but are not limited to Figure 3B The wristband-based device shown is a wearable device in place of a desktop system. This example focuses on optimizing piezoelectric transducers and evaluating transducer systems based on miniature piezoelectric film / foil (LDT0-028K-Measurement Specialties, Hampton, VA). Specifically, LDT0-028K is a flexible part consisting of a 28 μm thick piezoelectric PVDF polymer film with a polyester substrate laminated to 0.125 mm and equipped with two crimped contact points of screen-printed Ag-ink electrodes. When the piezoelectric film is subjected to motion, it is displaced from the mechanical neutral axis, and the bending produces very high strains and thus high voltages within the piezoelectric polymer. The resulting voltage can be directly interfaced to the analog-to-digital converter of a desktop data acquisition system or a stand-alone microcontroller system using a resistor network. In one embodiment, an...
example 2
[0124] In certain embodiments, a device is validated using non-invasive vascular waveform analysis for detection and staging of bleeding in humans. According to the Institutional Review Board, the inventors planned to enroll 50 patients undergoing coronary artery bypass surgery with normal ventricular and valve function. It is standard practice for patients to undergo preoperative autologous blood donation in order to preserve coagulation factors that are often depleted during cardiopulmonary bypass. Cardiac surgery also provides the opportunity to compare real-time changes in hemodynamic parameters with those of our device in a challenging heterogeneous group of patients.
[0125] Before starting surgery, patients were induced with general anesthesia and mechanically ventilated. Invasive monitors were inserted according to standard anesthesia protocol including central venous, pulmonary artery, and intra-arterial catheterization. Transesophageal echocardiography was routine...
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