Method and system for separating plasma protein from blood product by using diatomite

Abstract

The invention discloses a method and system for separating plasma protein from a blood product by using diatomite. The method for separating the plasma protein from the blood product by using the diatomite comprises the steps that the diatomite and equilibrium liquid are subjected to first stirring so that a homogeneous solution can be obtained; the homogeneous solution is conveyed through a conveying pipeline, and the homogeneous solution and the blood product which contains the plasma protein are subjected to second stirring to obtain a mixed solution; the mixed solution is subjected to filter-press processing to obtain the plasma protein. According to the method, an original diatomite solid adding mode is transformed into a liquid adding mode, dust is avoided from being produced in the adding process of the diatomite, and the homogeneous solution which contains the diatomite is added through the conveying pipeline, so that enclosed type adding of the diatomite is achieved, no dust is produced and no residue exists in the adding process, the adding amount of the diatomite can be controlled accurately, and the product can be avoided from being polluted.

Description

Technical field [0001] The present invention relates to the field of biopharmaceuticals, in particular, to a method for separating plasma proteins from blood products using diatomaceous earth and a system for separating plasma proteins from blood products. Background technique [0002] Diatomite is a kind of biogenic siliceous sedimentary rock dominated by diatom remains. Diatomite is often accompanied by biological remains. Various clay minerals (kaolinite hydromica, etc.) and detrital minerals coexist with it. Quartz, feldspar, etc.). In the blood product production process, diatomaceous earth is used as a filter aid to trap solid impurity particles suspended in the liquid on the surface and channel of the medium through sieving, depth effect, and adsorption, so as to achieve the purpose of solid-liquid separation . Diatomaceous earth is in the form of light powder, which is easy to produce dust when used. [0003] In the prior art, there are two ways to add diatomaceous earth...

AI Technical Summary

Problems solved by technology

The above-mentioned device is easy to generate dust during the diatomite addition process, and the device itself cannot be thoroughly cleaned and disinfected, resulting in secondary pollution, and there is a great potential pollution; diatomite is in the form of solid powder, and the feeding car is vacuum suction , there are residues, so the addition amount cannot be accurately controlled, and the operation is cumbersome, time-consuming and inefficient

[0004] Thus, the method of adding diatomaceous earth in the process of separating plasma protein from blood products needs to be improved

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