Method for modifying leukocyte filtration membrane
A filter membrane and white blood cell technology, applied in the field of white blood cell filtration, can solve the problems of increasing the effective surface area of the filter material in contact with blood, reducing the surface energy of the filter material and blood surface, increasing the wettability of the filter material, etc., to achieve obvious protection and stable properties , Improve the effect of surface wettability
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Embodiment 1
[0030] Embodiment 1 A kind of modification method of leukocyte filter membrane
[0031] The method for modifying the leukocyte filtration membrane comprises the steps of:
[0032] S1. Soak the polybutylene terephthalate nonwoven fabric filter membrane with polyoxyethylene lauryl ether solution for 24 hours, rinse once with ultrapure water, and then perform ultrasonic cleaning 3 times, each ultrasonic cleaning 10min, After finishing, place it in an oven at 80°C for drying;
[0033] S2. Soak the nonwoven fabric filter membrane treated in step S1 with a solution containing a photosensitizer, the bath ratio of the photosensitizer solution to the nonwoven fabric is 24:1, the soaking time is 18min, and the pressure is 5MPa; the photosensitizer The concentration of benzophenone in the solution is 0.15mol / L, and the concentration of 4,4'-bis(dimethylamino)benzophenone is 0.03mol / L; after soaking, high-energy ray irradiation is carried out under the protection of nitrogen flow. Accor...
Embodiment 2
[0037] Embodiment 2 A kind of modification method of leukocyte filter membrane
[0038] The method for modifying the leukocyte filtration membrane comprises the steps of:
[0039] S1. Soak the filter membrane of non-woven fabric with polyoxyethylene lauryl ether solution for 24 hours, rinse once with ultra-pure water, then perform ultrasonic cleaning, and dry in an oven at 80°C;
[0040] S2. Soak the non-woven fabric filter membrane treated in step S1 with a solution containing a photosensitizer, the bath ratio of the photosensitizer solution to the non-woven fabric is 24:1, the soaking time is 20min, and the pressure is 6.5MPa; The concentration of benzophenone in the photosensitizer solution is 0.16mol / L, and the concentration of 4,4'-bis(dimethylamino)benzophenone is 0.04mol / L; after soaking, the high-energy X-ray irradiation pretreatment for 10 minutes, the irradiation dose is 75kGy;
[0041] S3. Soak the non-woven fabric treated in step S2 with solution A again, the soa...
Embodiment 3
[0044] Embodiment 3 A kind of modification method of leukocyte filter membrane
[0045] The method for modifying the leukocyte filtration membrane comprises the steps of:
[0046] S1. Soak the filter membrane of non-woven fabric with polyoxyethylene lauryl ether solution for 24 hours, rinse once with ultra-pure water, then perform ultrasonic cleaning, and dry in an oven at 80°C;
[0047] S2. Soak the nonwoven fabric filter membrane treated in step S1 with a solution containing a photosensitizer, the bath ratio of the photosensitizer solution to the nonwoven fabric is 24:1, the soaking time is 15min, and the pressure is 3MPa; the photosensitizer The concentration of benzophenone in the solvent solution is 0.28mol / L, and the concentration of 4,4'-bis(dimethylamino)benzophenone is 0.08mol / L; after soaking, carry out high-energy radiation under the protection of nitrogen flow Irradiation pretreatment for 15 minutes, the irradiation dose is 75kGy;
[0048] S3. Soak the non-woven ...
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