Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of coated stem cell bone grafter and using method thereof

A stem cell and bone connector technology, applied in the field of medical devices, can solve the problems of difficult and precise control of memory performance and restoring force, and achieve the effect of simple setting method, various fastening methods, and uniform release of restoring force

Active Publication Date: 2019-06-21
GRINM MEDICAL INSTR BEIJING CO LTD
View PDF8 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a stem cell-coated bone adapter and its use method, which solves the problem that the memory performance and recovery force of the plate-shaped bone plate are not easy to be accurately controlled, and uses stem cells to promote osteoblast differentiation at the fracture site, thereby promoting Healing of Broken Bone

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of coated stem cell bone grafter and using method thereof
  • A kind of coated stem cell bone grafter and using method thereof
  • A kind of coated stem cell bone grafter and using method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Step 1: Use a titanium-nickel shape memory alloy wire with a diameter of 2 mm to wind a flat spring with an arch height of 60 mm, an arch width of 10 mm, and a length of 80 mm through a mold, such as figure 1 shown.

[0033] The second step: use a special mold to bend the flat spring into the shape of the curved flat spring 4, and then put the mold and the flat spring into a high-temperature heating furnace for heat preservation and shaping into the curved flat spring 4, such as figure 2 shown.

[0034] The third step is to use memory alloy thin plate wire cutting to cut into a memory alloy protection ring 1 with inward protrusion, and then keep it heat-preserved and shaped at high temperature, as shown in FIG. 8 . Then, the memory alloy protection ring 1 is deformed at low temperature and opened into an open state.

[0035] Step 4: Make a drug-loaded guard plate on the drug-loaded guard plate 2 made of pure titanium and coat the stem cell area 5, such as Figure 5s...

Embodiment 2

[0042] The first step: use a titanium-nickel shape memory alloy wire with a diameter of 1.5mm, and wind it through a mold to form a flat spring with an arch height of 70mm, an arch width of 10mm, and a length of 90mm.

[0043] Step 2: Use a special mold to bend the flat spring into the shape of the curved flat spring 4 , and then put the mold and the flat spring into a high-temperature heating furnace for heat preservation and shape the curved flat spring 4 .

[0044] The third step is to use memory alloy wire to bend into a memory alloy protection ring 1 with inward protrusion, and then heat and heat it to shape it at high temperature. Then, the memory alloy protection ring 1 is deformed at low temperature and opened into an open state.

[0045] Step 4: Make a drug-loaded guard plate coated with stem cell area 5 on the drug-loaded guard plate 2 made of titanium alloy TC4, pre-surface treatment by pickling, and then apply hydroxyapatite on the drug-loaded guard plate coated wi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a stem-cell coated bone fracture setting device. The device comprises medicine-carrying guard plates and a fastening device, bone fractures are fixed between two medicine-carrying guard plates, the middles of the medicine-carrying guard plates are provided with medicine-carrying guard plate stem-cell coating areas, the stem-cell coating areas are adjacent to the bone fractures, and the fastening device is used for fixing the two medicine-carrying guard plates. The fastening device is a bending flat spring and / or a memory alloy guard ring, the bending flat spring holds the two medicine-carrying guard plates tightly, and the memory alloy guard ring is fastened on one medicine-carrying guard plate in a clamping mode. The application method comprises the steps that firstly at a low temperature, the bending part of the tightly-held titanium-nickel memory alloy bending flat spring is opened and / or the U-type memory alloy guard ring is opened, so that the medicine-carrying guard plate stem cell coating areas are aligned to the bone fracture, then the opened bending flat spring is clamped on the outer sides of the medicine-carrying guard plates and ribs and / or inner lugs of the U-shape memory alloy guard ring and is aligned to through holes inside the medicine-carrying guard plates, after the deformation, the effect of fixing the upper and lower medicine-carrying guard plates and ribs is achieved.

Description

technical field [0001] The invention belongs to the technical field of medical instruments, and in particular relates to an osteosynthetic instrument for promoting the healing of broken bones such as ribs and a method for using the same. Background technique [0002] The human body is subjected to unexpected violent shocks, traffic accidents, and falling from heights, which can easily cause fractures of ribs and sternum, which will cause pain or affect the functions of the heart, lungs and other organs. By means of (minimally invasive) surgery, fixing the bone plate or bone setter on the broken parts of the ribs and sternum can fix and connect the broken bones and help the healing of the ribs and the like. [0003] TiNi shape memory alloys are widely used in biomedical fields due to their unique shape memory effect, excellent mechanical properties and biocompatibility. Chinese patent ZL201520376038.9 discloses a bone plate made of memory alloy memory properties. The princip...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61B17/80A61L31/08A61L31/00
CPCA61B17/80A61B17/8076A61B17/808A61B17/8085A61B2017/00884A61L31/005A61L31/08A61L2430/02
Inventor 袁志山崔跃李君涛缪卫东冯昭伟尚再艳王兴权
Owner GRINM MEDICAL INSTR BEIJING CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com