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Antibacterial anti-virus hand cream and preparation method thereof

A hand cream and anti-virus technology, applied in the field of medical supplies, can solve the problems of reduced protective effect of hand cream, loss of skin moisturizing properties, incomplete moisturizing agent effect, etc. The effect of maintaining the antiviral effect

Active Publication Date: 2017-10-20
广州德臻生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, many hand sanitizers are used in medical care, nursing care, and public places. These hand sanitizers generally contain high-concentration alcohol, silver ions, chlorhexidine and other bactericidal ingredients. They are generally liquid preparations or gel preparations. The common method of use is hand washing After application; for ease of use, quick-drying hand sanitizers have also appeared in recent years. In order to ensure quick-drying characteristics and improve the bactericidal effect, hand sanitizers generally contain high-concentration alcohol (about 75%), high-concentration alcoholic protein The denaturation effect is good, and it can have a bactericidal effect in a short period of time, but alcohol is an organic solvent, which can easily lead to sebum loss and sebum reduction, which in turn causes skin damage such as dryness, chapping, and inflammation of the user's skin, and skin damage leads to the loss of the cuticle protective layer , easily lead to infection, and at the same time, due to the fear of skin damage, it is easy to lead to the resistance of medical staff to hand hygiene, which in turn reduces the compliance of hand hygiene, and it is easy to become a source of nosocomial infection
[0003] In addition, it is reported that (Prevalence and correlates of skin damage on the hands of nurses. J. of Hospital infection (1987) 9.30-33) 25% of nurses have hand dermatitis, 85% of nurses have various skin problems, and some studies say that 50% The above medical staff have experienced hand skin damage and discomfort. The main reason is chronic irritation caused by repeated use of hand sanitizers and finger disinfectants, that is, high-concentration alcohol denatures keratin, destroys sebum and cutin protective layer, and makes the skin lose moisture. Cause skin damage; the damaged skin tends to become rough, produce dandruff, and form chapped skin, causing damage to the normal flora of the skin and increasing the risk of nosocomial infection expansion
[0004] In order to solve the skin damage caused by hand sanitizers, hand creams are generally recommended at home and abroad. However, due to the need for frequent hand washing and disinfection in the medical field, the protective effect of hand creams is greatly reduced; there are also some products that add moisturizers to disinfectants. However, due to the high alcohol content, the effect of the moisturizer is not complete. At the same time, the antibacterial effect of the liquid disinfectant decreases rapidly as the alcohol volatilizes. Although the gel disinfectant partially alleviates the problem of fast alcohol volatilization, it maintains The antibacterial activity time still cannot meet the needs of the site. At the same time, the gel-like disinfectant contains a thickener, which makes it feel bad after application
[0005] At present, there is no hand cream specifically for the characteristics of the medical field. The hand cream used by medical personnel is mainly for civilian use. The medical field needs to wash hands and disinfect frequently, and also needs to perform medical actions such as blood drawing and injection. General hand cream contains various It is a kind of spice, and it is sticky and slippery, which has a bad impression on patients, and it is easy to affect operations such as blood drawing and injection

Method used

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  • Antibacterial anti-virus hand cream and preparation method thereof
  • Antibacterial anti-virus hand cream and preparation method thereof
  • Antibacterial anti-virus hand cream and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1 A kind of antibacterial and antiviral hand cream

[0037] The antibacterial and antiviral hand cream of the present embodiment, described hand cream is prepared by the raw material of following weight:

[0038]

[0039]

[0040] The preparation method of the antibacterial and antiviral hand cream of the present embodiment comprises the following steps:

[0041] 1. Preparation of silver ion-amino group ligand compound

[0042] Take 23.2g of silver oxide (about 0.1 mole of silver ion) and 9g of ethylenediamine (about 0.3 mole of amino group), add 100g of gelatin, add water to 1000ml, stir at room temperature for 30 minutes, and obtain a viscous silver ion-amino group ligand Compound solution 1000ml.

[0043] 2. Preparation of lichen extract

[0044] After getting 100g lichen (purchased from the Alibaba website) and pulverizing, soak in 50% alcohol for 24 hours, filter and dry at low temperature for 24 hours to obtain 10g of paste, use Spectro X Sort ...

Embodiment 2

[0047] Embodiment 2 A kind of antibacterial and antiviral hand cream

[0048] The antibacterial and antiviral hand cream of the present embodiment, described hand cream is prepared by the raw material of following weight:

[0049]

[0050]

[0051] The preparation method of the antibacterial and antiviral hand cream of the present embodiment is the same as that of embodiment 1.

Embodiment 3

[0052] Embodiment 3 A kind of antibacterial and antiviral hand cream

[0053] The antibacterial and antiviral hand cream of the present embodiment, described hand cream is prepared by the raw material of following weight:

[0054]

[0055] The preparation method of the antibacterial and antiviral hand cream of the present embodiment is the same as that of embodiment 1.

[0056] The bactericidal and antibacterial experiment of the hand cream of Test Example 1 Embodiment 1~3

[0057] BHA medium (purchased from Qingdao Haibo Biotechnology Co., Ltd.) was prepared, and 5 laboratory examiners from Suzhou Fifth People's Hospital conducted the experiment.

[0058] Before washing hands, put both hands on BHA medium and incubate at 37°C for 24 hours as a control. After hand washing and disinfection, apply the hand cream of Examples 1 to 3 to the right hand, and use 1% glucose chlorhexidine + 75% alcohol disinfectant to disinfect the left hand , double-printed to BHA medium for cult...

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Abstract

The invention discloses antibacterial anti-virus hand cream and a preparation method thereof. The hand cream is prepared from the raw materials including a silver ion-amino group ligand compound solution, ethanol, emulsion stabilizer, a non-ionic surfactant, a lichen extract, glycerine, water and the like, wherein in the silver ion-amino group ligand compound solution, the proportion of silver ion and amino groups is 1 to 3, and the molar volume ratio of the silver ion to the silver ion-amino group ligand compound solution is 1 to (10000 to 100000). The hand cream adopted by the invention integrates effects of resisting bacteria, resisting virus and protecting skin; after hand-washing, the hand cream is sterilized without using a disinfectant, and the hand cream is directly applied to the hands to play an antibacterial effect, so that the hand cream is convenient to use and the bactericidal and antibacterial activity can be maintained for a long time; an antibacterial effect can be maintained for not less than 3 hours, so that nosocomial infection caused by poor compliance of hand washing is reduced.

Description

technical field [0001] The invention belongs to the technical field of medical supplies, and more specifically, the invention relates to an antibacterial and antiviral hand cream and a preparation method thereof. Background technique [0002] At present, many hand sanitizers are used in medical care, nursing care, and public places. These hand sanitizers generally contain high-concentration alcohol, silver ions, chlorhexidine and other bactericidal ingredients. They are generally liquid preparations or gel preparations. The common method of use is hand washing After application; for ease of use, quick-drying hand sanitizers have also appeared in recent years. In order to ensure quick-drying characteristics and improve the bactericidal effect, hand sanitizers generally contain high-concentration alcohol (about 75%), high-concentration alcoholic protein The denaturation effect is good, and it can have a bactericidal effect in a short period of time, but alcohol is an organic s...

Claims

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Application Information

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IPC IPC(8): A61K8/9733A61K8/81A61K8/19A61K8/31A61K8/34A61K8/36A61K8/37A61Q17/00A61Q19/00A61P17/00A61P31/02
CPCA61K8/19A61K8/31A61K8/342A61K8/345A61K8/361A61K8/375A61K8/8129A61K8/97A61Q17/005A61Q19/00A61Q19/007
Inventor 金京勋崔红易梅仙易其
Owner 广州德臻生物技术有限公司
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