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A method of using Agaricus blazei polysaccharide to resist Eimeria in livestock and poultry breeding

A technology of Agaricus blazei polysaccharide and Eimeria coccidia can be used in pharmaceutical formulations, anti-infective drugs, medical preparations containing active ingredients, etc. and other problems to achieve good growth and development

Active Publication Date: 2020-02-14
TIANJIN AGRICULTURE COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, because the use of anticoccidial chemical drugs can easily lead to the emergence of drug-resistant strains, and long-term use will cause harm to drug residues, and Agaricus blazei polysaccharides are safe to use. As a candidate anticoccidial drug, it has important The research significance and application value of
[0008] In recent years, more and more studies have proved that Agaricus blazei polysaccharides have the effect of resisting endoparasite infection, but the immune regulation effect of Agaricus blazei polysaccharides on other endoparasitic protozoa has not been studied in detail. The impact of mouse body weight and immune organs of Otococcus, the impact of Agaricus blazei polysaccharide on the amount of oocyst excretion of chicks infected with Eimeria tenella, etc. are to be continuously explored by those skilled in the art

Method used

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  • A method of using Agaricus blazei polysaccharide to resist Eimeria in livestock and poultry breeding
  • A method of using Agaricus blazei polysaccharide to resist Eimeria in livestock and poultry breeding
  • A method of using Agaricus blazei polysaccharide to resist Eimeria in livestock and poultry breeding

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Embodiment Construction

[0025] The implementation of the present invention will be described in further detail below in conjunction with the accompanying drawings. The following embodiments are only descriptive, not restrictive, and cannot limit the protection scope of the present invention.

[0026] In the first step, in order to find out the application method of Agaricus blazei polysaccharide, the present invention will at first determine the optimal infection dose of Eimeria falciparum, and the specific method steps are:

[0027] (1) 40 30-day-old female Kunming mice were adaptively fed for 3 days, randomly divided into 4 groups, 10 mice in each group, and the mice in the first group, the second group, and the third group were respectively 500 mice per mouse , 5000 / only, and 50000 / only Eimeria falciparum doses were infected orally, and the fourth group was fed with an equal amount of normal saline.

[0028] (2) Observe for 10 days after infection, and record the clinical symptoms such as mental s...

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Abstract

The invention relates to a method for resisting Eimeria through agaricus blazei murill polysaccharide in livestock and poultry breeding. The method comprises that livestock and poultry take in 100 mg / kg of agaricus blazei murill polysaccharide on the basis of body weight in livestock and poultry breeding so that the livestock and poultry can resist Eimeria infection. The method comprises stirring agaricus blazei murill polysaccharide and feed, and feeding livestock and poultry with the mixture or an aqueous solution of agaricus blazei murill polysaccharide or through precise manual drenching. The livestock and poultry take in 100 mg / kg of agaricus blazei murill polysaccharide on the basis of body weight so that the livestock and poultry can effectively resist Eimeria infection and the agaricus blazei murill polysaccharide well protects the growth and development of immune organs of breeding livestock and poultry.

Description

technical field [0001] The invention belongs to the technical field of extracting traditional Chinese medicines, and in particular relates to the anti-parasitic application of Agaricus blazei polysaccharide in livestock and poultry breeding. Background technique [0002] Agaricus Blazei Murrill (ABM) is produced in Brazil. It is delicious and can enhance the immune regulation function of the body. It has anti-virus, anti-bacterial, anti-parasitic infection, and anti-tumor functions. [0003] Studies have found that the active ingredient of Agaricus blazei polysaccharide can significantly enhance humoral immunity and cellular immune response, indicating that the active ingredient of this polysaccharide can stimulate Th1 immunity and can be used as a new type of immune adjuvant for research and development. Agaricus blazei polysaccharides activate killer cells (NK cells) through interleukin-12 (IL-12)-induced secretion of interferon-γ (IFN-γ), thereby promoting innate immune r...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61P33/02
CPCA61K31/715
Inventor 任超马吉飞贾妮娜袁顺子周宇晴冼水凤
Owner TIANJIN AGRICULTURE COLLEGE