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Hepatitis C virus antibody saliva detection kit

A hepatitis C virus and saliva detection technology, which is applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve the problems of low antibody content in saliva and decreased detection sensitivity, and achieve clear results, high coincidence rate, and high detection efficiency Effect

Inactive Publication Date: 2017-10-20
河南爱微迪生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to solve the problem of low antibody content in saliva, which leads to a decrease in detection sensitivity

Method used

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Embodiment Construction

[0009] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Apparently, the described embodiments are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0010] In the embodiment of the present invention, a hepatitis C virus antibody saliva detection kit, including the recombinant protein GL (rGL) labeled with gold on the glass fiber and the quality control antigen, the detection line and the quality control line on the nitrocellulose membrane Recombinant Hepatitis C Antigen (HCV Ag) and quality control monoclonal antibody are respectively coated on the site, and are used to detect specific antibodies against Hepatitis C Virus ...

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Abstract

The invention discloses a hepatitis C virus antibody saliva detection kit. The kit includes a flowering gold labeled recombinant protein GL (rGL) and a quality control antigen on glass fiber, hepatitis C antigen detection, a recombinant HCV Ag and a quality control monoclonal antibody coating a detection line and a quality control line of nitrocellulose membrane, and a specific antibody for detecting anti-hepatitis C virus in human saliva. The kit provided by the invention has high total consistent rate, can be used for non-invasive detection, and is convenient for invasive detection of serum, at the same time the result display is clear, and the detection efficiency is higher.

Description

technical field [0001] The invention relates to the field of hepatitis C detection, in particular to a hepatitis C virus antibody saliva detection kit. Background technique [0002] The antibody content in saliva is about 1 / 50 to 1 / 800 of that in serum. Compared with serum, its antibody content is very small, and the sensitivity of detecting anti-HCV antibody in saliva with blood detection HCV antibody kit is too low. The indirect method used to detect HIV antibodies in saliva has been released, which can non-invasively detect HIV antibodies in saliva. In order to solve the problem of low antibody content in saliva, which leads to a decrease in detection sensitivity. The present invention adopts a new type of colloidal gold particle, that is, gold flower, that is, on the basis of the conventional colloidal gold particle preparation method, the gold particle (10-20nm in diameter) is used as the gold seed, and the gold The seed particles grow as multiple gold particle aggre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/577G01N33/576
CPCG01N33/577G01N33/576
Inventor 杨卫平王永强
Owner 河南爱微迪生物技术有限公司
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