The invention discloses an igniter reagent of an airbag device. The igniter reagent comprises the following raw material components in percentage by mass: 20-45% of a combustible agent, 50-78% of an oxidant, 0.5-5% of a combustion improver and the balance of an adhesive, wherein the total mass percentage of the components is 100%. A preparation method of the igniter reagent comprises the following steps: performing wet mixing on the raw materials, cutting a reagent into spheres, putting the spheres into a granulator for pelletizing, screening uniform reagent granules, and finally drying the regent, thereby obtaining the igniter reagent. The igniter reagent disclosed by the invention has a good ignition function, is relatively low in percussion sensitivity degree, friction sensitivity degree and static electric spark sensitivity degree, is not self-combusted when being heated, collided and the like, is relatively high in security in both the production process and the use process, and is simple in preparation method, low in raw material price, low in cost, applicable to large-scale on-batch production and relatively high in cost performance.