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Application of aizoon stonecrop herb extract in preparing medicine for inhibiting acnes

A technology of sedum notoginseng and extracts, applied in the directions of drug delivery, drug combination, plant/algae/fungus/moss components, etc., to achieve the effects of relieving itching, safe use and convenient preparation

Inactive Publication Date: 2017-11-24
张东旭
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no relevant literature report about Sedum Sanqi treating acne or comedones

Method used

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  • Application of aizoon stonecrop herb extract in preparing medicine for inhibiting acnes
  • Application of aizoon stonecrop herb extract in preparing medicine for inhibiting acnes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Sedum notoginseng extract is prepared through the following steps:

[0023] Step 1: Take fresh sedum notoginseng, remove impurities, wash with water, moisten and soften, cut into small pieces, freeze at -20°C, put in a freeze dryer (Denmark, Labogene), freeze to -100°C, pump Vacuum until the pressure in the drying chamber is below 20Pa for sublimation and drying. After 30 hours of sublimation, take it out and seal it for packaging.

[0024] Step 2:

[0025] Freeze-dried Sedum notoginseng 100g, crushed, added 1000mL of distilled water, coarsely filtered with gauze, kept the filtrate, adjusted the pH value to 6.8, then centrifuged at 1600r / min for 15min, and took the supernatant for later use.

[0026] Among the 80 patients with acne, 44 were males and 36 were females, aged between 16 and 25 years old. The patient's acne site is on the forehead or face, and 2 mL of the water extract of sedum notoginseng is applied to the forehead, and the other part of the face is smear...

Embodiment 2

[0033] Sedum notoginseng extract is prepared through the following steps:

[0034] Step 1: Take fresh sedum notoginseng, remove impurities, wash with water, moisten and soften, cut into small pieces, freeze at -20°C, put in a freeze dryer (Denmark, Labogene), freeze to -120°C, pump Vacuum until the pressure in the drying chamber is below 20Pa for sublimation and drying. After 30 hours of sublimation, take it out and seal it for packaging.

[0035] Step 2: 100g of freeze-dried sedum notoginseng, mash it, add 1000mL of distilled water, filter the discarded residue, adjust the pH value to 7.0, then centrifuge at 1000r / min for 30min, and take the supernatant for later use.

[0036] Among 100 patients with acne, 48 males and 52 females were selected, aged between 16 and 25 years old. The patient is divided into two groups at random, and one group is the group of the present invention, gets the water extract 2mL of sedum notoginseng and smears the itching part; Apply 2 mL of treti...

Embodiment 3

[0043] Sedum notoginseng extract is prepared through the following steps:

[0044] Step 1: Take fresh sedum notoginseng, remove impurities, wash with water, moisten and soften, cut into small pieces, freeze at -20°C, put in a freeze dryer (Denmark, Labogene), freeze to -150°C, and pump Vacuum until the pressure in the drying chamber is below 20Pa for sublimation and drying. After 30 hours of sublimation, take it out and seal it for packaging.

[0045] Step 2: 100g of freeze-dried sedum notoginseng, mash it, add 1000mL of distilled water, filter the residue, adjust the pH value to 7.2, centrifuge at 1800r / min for 20min, and take the supernatant for later use.

[0046] Clinical application

[0047] 1. Apply the present invention to 250 cases of acne patients, 133 cases of males, 117 cases of females, aged 15-25 years, 32 cases of which are accompanied by secondary infection, use cotton swabs to dip 2 mL of the water extract of Sedum notoginseng and apply it on the skin On the ...

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Abstract

The invention provides application of an aizoon stonecrop herb extract in preparing a medicine for inhibiting acnes. The aizoon stonecrop herb extract is a water extracting solution of aizoon stonecrop herb after freeze-drying. The aizoon stonecrop herb extract can reach the function of effectively improving and relieving papules, nodules, pustules, cysts, pruritus, swelling and the like of acnes.

Description

technical field [0001] The invention belongs to the new application field of sedum notoginseng, and in particular relates to the application of a sedum notoginseng extract in the preparation of anti-acne drugs. Background technique [0002] Sedum notoginseng (Aizoon Stonecrop Herb) is the dry whole herb of Sedum notoginseng Sedum aizoon L. in the sedum family Sedum, widely distributed in Fujian, Zhejiang, Jiangsu, Henan and other provinces in my country. The medicine has the effects of stopping bleeding, dispelling blood stasis, calming the nerves, and detoxifying. It is commonly used in the folks for insomnia, pain relief, bruises, and especially the treatment of various hemorrhagic diseases. It has the effects of clearing heat and detoxifying, dispelling wind and resolving phlegm, promoting blood circulation and relieving pain. Its oral administration can treat febrile convulsions, dysentery, pneumonia, pharyngitis and hepatitis in children, etc., and external application...

Claims

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Application Information

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IPC IPC(8): A61K36/41A61P17/10A61P17/04A61P29/00
CPCA61K9/0014A61K36/41A61K2236/331A61K2236/53
Inventor 张东旭
Owner 张东旭
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