Method for measuring turbid medium optical parameter based on deficient P3 approximation forward model

A forward model, optical parameter technology, used in phototherapy, diagnostic recording/measurement, radiotherapy, etc., to achieve the effect of concise expression and fast solution speed

Inactive Publication Date: 2017-12-01
TIANJIN UNIV
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Problems solved by technology

In addition, although the analytical expression method based on DA approximation avoids the non-uniqueness of the solution in the fitting algorithm, this method is only applicable when the DA approximation condition is satisfied, that is, high a'[6]

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  • Method for measuring turbid medium optical parameter based on deficient P3 approximation forward model
  • Method for measuring turbid medium optical parameter based on deficient P3 approximation forward model
  • Method for measuring turbid medium optical parameter based on deficient P3 approximation forward model

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[0056] Example: Measured value L with emissivity m (r,θ i ), L m (r′,θ i )i=0,...,3, the measured medium is μ configured with India ink and 20% Intralipid a =0.5mm -1 , μ′ s =0.5mm -1 Take the liquid phantom as an example, where r and r' are selected as 5mm and 10mm, θ 0 , θ 1 , θ 2 and θ 3 Selected as 40°, 80°, 120° and 160°, the measurement system used is a steady-state emissivity interstitial measuring device system, and the main structure (see patent application number 201610822322.3) is: including a light source module, a detection module, a displacement Module and control module; the light source module includes a tungsten halogen lamp connected to one end of the light source fiber; the other end of the light source fiber is provided with an isotropic scattering head for converting the light emitted by the tungsten halogen lamp into a point light source The detection module includes a side-illuminated optical fiber and a spectrometer, one end of the side-illumi...

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Abstract

The invention discloses a method for measuring turbid medium optical parameter based on a deficient P3 approximation forward model. The method mainly comprises the steps of building a radiant deficient P3 approximation forward model, an analysis algorithm based on deficient P3 approximation forward model optical parameter reverse construction is developed, and therefore an absorption coefficient and a reduction scattering coefficient of a measured turbid medium are obtained. Compared with traditional P3, the developed deficient P3 is simpler in formula, and compared with a scattering approximation, light diffusion in large-absorption or small-scattering tissue is more accurately described; according to the developed algorithm based on deficient P3 analysis reverse construction, compared with the traditional P3 approximation based fitting algorithm and the analysis reverse construction algorithm based on diffusion approximation, large-absorption and small-scattering turbid medium optical parameters can be more accurately constructed. According to the analysis reverse construction algorithm, the solving speed is high, and the method is expected to be applied to online monitoring of optical parameters. According to the measuring method, the light source intensity adopted by measuring experiments does not need to be measured, and practical application is facilitated.

Description

technical field [0001] The invention belongs to the field of optical parameter measurement in tissue optics research, and specifically relates to an incomplete P3 approximate forward model and an analytical inversion algorithm developed based on the forward model to obtain optical parameters and absorption coefficients of turbid media (tissues). and the reduced scattering coefficient. Background technique [0002] Optical parameter measurement has received extensive attention in the field of biomedical photonics. Especially in laser therapy, the measurement of optical parameters in vivo can be used to calculate the luminous flux to achieve the purpose of online optimization of light dose [1,2]. Steady-state measurement technology is commonly used in the measurement of optical parameters of turbid media (tissues) due to its simple equipment and low cost [3-5]. Although surface diffuse reflectance measurement can be used for non-invasive optical parameter measurement of tiss...

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Application Information

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IPC IPC(8): A61B5/00A61N5/067G06F19/00
CPCA61B5/0059A61N5/06A61N2005/0626A61N5/067
Inventor 赵会娟刘玲玲万文博高峰
Owner TIANJIN UNIV
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