Unlock instant, AI-driven research and patent intelligence for your innovation.

Application of peony blossom extracts to preparation of drugs for treating benign prostate hyperplsia

A technology of prostatic hyperplasia and peony flower, which is applied in the field of medicine, can solve the problems of prostatic hyperplasia without peony flower extract, and achieve the effect of developing medicinal value, rich raw materials, and simple preparation method

Inactive Publication Date: 2017-12-05
HENAN UNIV OF CHINESE MEDICINE
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far there is no public report on the use of peony flower extract in the treatment of benign prostatic hyperplasia

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of peony blossom extracts to preparation of drugs for treating benign prostate hyperplsia
  • Application of peony blossom extracts to preparation of drugs for treating benign prostate hyperplsia
  • Application of peony blossom extracts to preparation of drugs for treating benign prostate hyperplsia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] The specific implementation of the present invention will be described in detail below in conjunction with the examples.

[0008] The present invention is an application of peony flower extract as the only active ingredient in the preparation of drugs for the treatment of benign prostatic hyperplasia. Peony flower 10 times the weight of petroleum ether at 30-60°C, reflux extraction for 1 hour, degrease, discard the petroleum ether extract; peony flower dregs evaporated to dry petroleum ether, add 10 times the weight of peony flower, soak in 80% ethanol for 0.5h , reflux for extraction for 1 hour, filter to obtain the filtrate for the first time; add ethanol with 10 times the weight of peony flower and 80% mass concentration to the dregs, extract for 1 hour under reflux, filter to obtain the second filtrate, combine the two filtrates, and recover under reduced pressure Ethanol until there is no alcohol smell, add distilled water to disperse to a dispersion equivalent to ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention aims to provide application of peony blossom extracts to preparation of drugs for treating benign prostate hyperplasia. Dried peony blossoms are smashed into coarse powder, petroleum ether 30-60 DEG C is added first, reflux extraction and degreasing are conducted, and a petroleum ether extracting solution is discarded; petroleum ether is volatilized to dryness by means of peony blossom residues, ethyl alcohol is added for immersion, reflux extraction is conducted, filtration is conducted twice, filtrates obtained twice are combined, depressurizing recovery of ethyl alcohol is conducted till no alcohol taste exists, distilled water is added for dispersion to obtain a dispersion liquid equivalent to contain 0.3 g / mL of crude drugs, the dispersion liquid is treated with AB-8 macroreticular resin, elution with distilled water is conducted first, and an aqueous liquid is discarded; elution with ethyl alcohol is then conducted, and an elution liquid is discarded; and elution with ethyl alcohol is conducted again, an ethyl alcohol elution liquid is collected, depressurizing recovery of ethyl alcohol is conducted till no alcohol taste exists, and freeze drying and smashing are conducted to obtain peony blossom extracts. The raw materials of the extracts are rich, the preparation method is simple, the cost is low, peony blossoms can be effectively used for treating benign prostate hyperplasia as the only active ingredient, the medicinal value of peony blossoms is extended, and economic and social benefits are high.

Description

technical field [0001] The invention relates to medicines, in particular to the application of a peony flower extract in the preparation of medicines for treating hyperplasia of the prostate gland. Background technique [0002] In the early stage of benign prostatic hyperplasia, due to compensation, the symptoms are not typical. With the aggravation of lower urinary tract obstruction, the symptoms gradually become more obvious. The clinical symptoms include storage symptoms, micturition symptoms and post-micturition symptoms. Due to the slow progression of the disease, it is difficult to determine the time of onset. 1. Storage period symptoms: frequent urination, nocturia; 2. Urinary urgency, urinary incontinence; 3. Voiding period symptoms: dysuria; 3. Post-micturition symptoms: incomplete urination, increased residual urine. [0003] The root of Paeoniae officinalis is fresh and crisp and juicy, and can be used for medicine. According to analysis, Radix Paeoniae Alba con...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K36/65A61P13/08A61K133/00
CPCA61K36/71A61K36/65A61K2236/15A61K2236/333A61K2236/35A61K2236/39A61K2236/51A61K2236/55
Inventor 苗明三代丽萍许二平
Owner HENAN UNIV OF CHINESE MEDICINE