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Prediction method and prediction system of irresponsive gamma globulin Kawasaki disease

A technology of gamma globulin and prediction method, which is applied in the field of prediction method and prediction system of gamma globulin non-responsive Kawasaki disease, which can solve the problem of different incidence rates of Kawasaki disease patients and difficult to predict the complications of gamma globulin non-response in Kawasaki disease Symptoms, no statistically significant differences in total scores, etc., to achieve the effect of reducing the probability of coronary artery injury, shortening the length of hospitalization, and shortening the duration of fever

Inactive Publication Date: 2017-12-15
SOOCHOW UNIV AFFILIATED CHILDRENS HOSPITAL +1
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AI Technical Summary

Problems solved by technology

The incidence of Kawasaki disease patients of various races is different, and there are differences in different regions. There is no statistically significant difference in the individual indicators and the total score. It is difficult to predict the complications of gamma globulin unresponsiveness in Kawasaki disease

Method used

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  • Prediction method and prediction system of irresponsive gamma globulin Kawasaki disease
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  • Prediction method and prediction system of irresponsive gamma globulin Kawasaki disease

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Embodiment Construction

[0058] The present invention will be described in detail below with reference to the embodiments shown in the accompanying drawings. However, the embodiments do not limit the present invention, and any structural, method, or functional changes made by those skilled in the art according to these embodiments are included in the protection scope of the present invention.

[0059] Such as figure 1 as shown, figure 1 It is the prediction method of gamma globulin non-responsive Kawasaki disease provided by the first embodiment of the present invention, the method comprising:

[0060] S1. Collect 21 original parameters for establishing the SVM model;

[0061] The original parameters of the modeling include: gender, age, fever time when visiting a doctor, clinical type, CRP detection value, WBC value, PLT value, HB value, ALT value, AST value, ALB value, gamma globulin use time, and Clinical diagnostic symptom indicators; the clinical diagnostic symptom indicators include: conjunct...

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Abstract

The invention provides a prediction method and prediction system of an irresponsive gamma globulin Kawasaki disease. The method comprises the following steps that 21 original parameters of SVM model building are collected; the modelling original parameters comprise gender, age, fever time during treatment, clinical classification, CRP detection value, WBC value, PLT value, Hb value, ALT value, AST value, ALB value, gamma globulin using time and clinical diagnosed symptom indicators; the clinical diagnosed symptom indicators comprise conjunctival injection, erythra, cracked lips, a strawberry-like tongue, lymphadenectasis of a neck, hard and swollen hands and feet, digit peeling, crissum peeling and a red and swollen bacillus calmette-guerin scar; discretization is conducted on the original parameters to obtain SVM characteristic values corresponding to the original parameters; the SVM characteristic values are regarded as base data, a SVM model is built, and through the SVM model, a complication with irresponsive gamma globulin of the Kawasaki disease is predicted. By means of the prediction method and prediction system, early intervening treatment can be conducted on a patient, recovery of damage to a coronary artery is promoted, and the prediction method and prediction system have important significance and value on diagnosis and treatment of the Kawasaki disease in the future.

Description

technical field [0001] The invention belongs to the field of ultrasonic diagnostic imaging, and relates to a prediction method and a prediction system for gamma globulin non-responsive Kawasaki disease. Background technique [0002] Kawasaki disease (Kawasaki disease, KD) is a systemic vasculitis syndrome that occurs in young children. It was reported for the first time in 1967 by the Japanese scholar Tomisaku Kawasaki. A large number of epidemiological investigations have shown that the disease has the characteristics of a high incidence in Asian populations, obvious seasonality, a high incidence in males, and a high incidence in infants and young children. Kawasaki disease is currently recognized internationally as the first cause of acquired heart disease in children. In 2004, the American Heart Association proposed based on evidence-based medicine that endothelial dysfunction (ECD) in Kawasaki disease may be a new risk factor for coronary atherosclerosis and ischemic h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/00G06K9/62
CPCG16H50/30G06F18/2411
Inventor 吕海涛黎璇江振荣张建敏周万平侯淼唐孕佳黄洁丁粤粤
Owner SOOCHOW UNIV AFFILIATED CHILDRENS HOSPITAL
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