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Volatile oil-containing traditional Chinese medicine composition for treating pediatric asthma as well as preparation method and application of traditional Chinese medicine composition

A technology for children's asthma and a composition is applied in the field of traditional Chinese medicine compositions containing volatile oil for the treatment of children's asthma and the preparation field thereof, so as to achieve the effects of relieving bronchospasm and regulating immune imbalance

Inactive Publication Date: 2017-12-22
SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the prior art, there is no report about the Chinese medicine composition containing volatile oil of the present invention for treating children's asthma.

Method used

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  • Volatile oil-containing traditional Chinese medicine composition for treating pediatric asthma as well as preparation method and application of traditional Chinese medicine composition
  • Volatile oil-containing traditional Chinese medicine composition for treating pediatric asthma as well as preparation method and application of traditional Chinese medicine composition
  • Volatile oil-containing traditional Chinese medicine composition for treating pediatric asthma as well as preparation method and application of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The preparation of embodiment 1 pharmaceutical preparation of the present invention

[0034] Take Chinese medicine raw materials: 2 parts of ephedra, 3 parts of bitter almond, 3 parts of radish seed, 3 parts of perilla seed, 1 part of white mustard seed, 3 parts of Tingli seed, 2 parts of dried ginger, 2 parts of peach kernel, 2 parts of earthworm, 2 parts of pepper 2 servings. Weigh the raw material drug according to the stated weight, add 8-10 times the amount of water, decoct, slightly boil 2 times, each time for 60-90min, combine the decoction liquid, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.20-1.30 (measured at 60°C). While decocting and extracting, the volatile oil and aromatic water mixture produced during the decoction are collected by a collecting device, wrapped with auxiliary materials (cyclodextrin), and fully mixed with the decoction extract. Add appropriate amount of excipients (dextrin), granulate with the c...

Embodiment 2

[0035] The preparation of embodiment 2 pharmaceutical preparations of the present invention

[0036] Take Chinese medicine raw materials: 2 parts of ephedra, 4 parts of bitter almond, 4 parts of radish seed, 4 parts of perilla seed, 2 parts of white mustard seed, 4 parts of Tingli seed, 2 parts of dried ginger, 2 parts of peach kernel, 2 parts of earthworm, 2 parts of pepper 2 servings. Weigh the raw material drug according to the stated weight, add 8-10 times the amount of water, decoct, slightly boil 2 times, each time for 60-90min, combine the decoction liquid, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.20-1.30 (measured at 60°C). While decocting and extracting, the volatile oil and aromatic water mixture produced during the decoction are collected by a collecting device, wrapped with auxiliary materials (cyclodextrin), and fully mixed with the decoction extract. Add appropriate amount of excipients (dextrin), granulate with the...

Embodiment 3

[0037] The preparation of embodiment 3 pharmaceutical preparations of the present invention

[0038] Take Chinese medicine raw materials: 2 parts of ephedra, 3 parts of bitter almond, 3 parts of radish seed, 3 parts of perilla seed, 1 part of white mustard seed, 4 parts of Tingli seed, 2 parts of dried ginger, 2 parts of peach kernel, 3 parts of earthworm, 3 parts of pepper 3 copies. Weigh the raw material drug according to the stated weight, add 8-10 times the amount of water, decoct, slightly boil 2 times, each time for 60-90min, combine the decoction liquid, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.20-1.30 (measured at 60°C). While decocting and extracting, the volatile oil and aromatic water mixture produced during the decoction are collected by a collecting device, wrapped with auxiliary materials (cyclodextrin), and fully mixed with the decoction extract. Add appropriate amount of excipients (dextrin), granulate with the co...

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Abstract

The invention discloses a volatile oil-containing traditional Chinese medicine composition for treating pediatric asthma. The traditional Chinese medicine composition is mainly prepared from the following raw materials in parts by weight: 2 parts of ephedra herb, 3-4 parts of semen armeniacae amarum, 3-4 parts of semen raphani, 3-4 parts of fructus perillae, 1-2 parts of semen brassicae, 3-4 parts of semen lepidii, 2 parts of rhizoma zingiberis, 2 parts of semen persicae, 2-3 parts of earthworm and 2-3 parts of bunge pricklyash seed. The preparation method comprises the following steps: (1) weighing the raw material medicines according to the weight part, adding water into the weighed raw material medicines, wherein the adding amount of the water is 8-12 times of the weight of the raw material medicines; extracting for twice, wherein the extraction of each time lasts for 60-90min; mixign decoction liquid, filtering out, and carrying out concentration under reduced pressure on filtrate; (2) when water decoction and extraction are carried out, collecting volatile oil and aromatic water mixture which are produced in a water decoction process, coating with auxiliary materials, then fully mixing the product with extracts obtained by means of water decoction so as to obtain a mixture. Pharmacological research proves that the traditional Chinese medicine composition has the functions of relieving cough and asthma, relieving bronchial spasm and adjusting immunological imbalance.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition containing volatile oil for treating children's asthma, its preparation method and application. Background technique [0002] Asthma is a frequently-occurring and common disease in children, which seriously impairs children's growth and development and physical and mental health. The prevalence trend of childhood asthma in my country is consistent with other countries in the world. The incidence rate is at the middle level in the world, and the mortality rate is at a high level. The crude mortality rate of asthma residents in my country surveyed from 2004 to 2005 was 2.45 / 100,000, and the standardized mortality rate It was 2.14 / 100,000. Therefore, medical and health institutions should increase their attention and investment in research on the treatment and control of children's asthma. [0003] In recent years, the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K47/69A61K9/16A61P11/06A61K35/62
CPCA61K9/1652A61K35/62A61K36/17A61K36/31A61K36/535A61K36/736A61K36/758A61K36/9068A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 虞坚尔张新光薛征白莉刘斐明溪李利清吴杰
Owner SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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