Ultrasonic method for measuring temperature change of biological tissue based on thermal expansion and gating algorithm

Abstract

The invention discloses an ultrasonic method for measuring temperature change of biological tissue based on thermal expansion and gating algorithm. Aiming at the problem that temperature increment ofa target area cannot be effectively monitored in methods for treating diseases based on various current body tissue heating modes, a method for evaluating the temperature change of the biological tissue by using B-mode ultrasound RF signals is established. According to the method, methods such as focused ultrasound, radio frequency and microwave are used for locally heating the biological tissue,B-mode ultrasound is used for imaging the target area and collecting the RF signals of the target area, a target frame is selected based on B-mode ultrasound timing sequence images, time delay imagesthat ultrasound passes through the tissue are calculated, and accordingly temperature change images are obtained; according to images outside a heating area, the coefficient of a self-adaption filteris calculated, and the obtained temperature change images are subjected to noise suppression. According to the ultrasonic method, the error in the temperature increment range of 18 DEG C is smaller than or equal to 2 DEG C, the temperature increment monitoring technology of B-mode ultrasound is promoted to be applied to thermal therapy, and the safety and effectiveness of the thermal therapy can be remarkably improved.

Description

technical field [0001] The invention relates to a method for ultrasonic temperature measurement of biological tissues, which is based on the thermal expansion effect of biological tissues, using B-ultrasound RF signals, and combining physiological gating and adaptive filter noise reduction technology to measure temperature changes with high precision The method; Belongs to the field of medical equipment. Background technique [0002] In recent years, as an emerging tumor treatment method, hyperthermia has attracted widespread attention, and has achieved great success in the treatment of uterine leiomyoma and breast cancer. Hyperthermia methods include high-intensity focused ultrasound (HIFU), microwave ablation, radiofrequency ablation, etc. The mechanism of which is to kill cancer cells by heating up. However, in the process of hyperthermia, if the temperature of the target area rises too high, it may cause damage to the normal cells around the target area, resulting in se...

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Problems solved by technology

[0010] Chinese patent application number: CN201410856098.0 "Ultrasonic temperature imaging method based on plane wave". Mention applications in biological tissue

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