Biological tissue characteristic parameter representation method based on single-needle actual measurement

A technology of characteristic parameters and biological tissue, applied in special data processing applications, electrical digital data processing, instruments, etc., can solve problems such as the inability to accurately obtain temperature field distribution, improve scientificity and reliability, improve accuracy, and solve Effects that cannot be precisely characterized

Inactive Publication Date: 2018-01-12
BEIJING UNIV OF TECH
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Problems solved by technology

[0004] Aiming at the problem in the prior art that the temperature field distribution cannot be accurately obtained due to the uncertainty of biological tissue characteristic parameters, the present invention proposes a biological tissue characteristic parameter characterization method based on single-needle measurement, through parameter sensitivity analysis and single Accurate characterization of tissue characteristic parameters is obtained through actual measurement, and then an accurate temperature field model in the process of radiofrequency thermal ablation is obtained through simulation technology

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  • Biological tissue characteristic parameter representation method based on single-needle actual measurement
  • Biological tissue characteristic parameter representation method based on single-needle actual measurement
  • Biological tissue characteristic parameter representation method based on single-needle actual measurement

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Embodiment Construction

[0035] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0036]In this embodiment, the radiofrequency ablation device is an ablation instrument RFA-I (Blade Co., Ltd., Beijing, China), the working electrode is an umbrella electrode RFA-1315, and there are 13 sub-electrodes, of which the diameter of the main electrode is 0.9mm , the length is 150mm, the sub-electrodes are evenly distributed around the main electrode, the diameter is 0.3mm, the length is 150mm, the angle between adjacent sub-electrodes is 55°, the temperature measuring needle used in the experiment is YWY-2 (Kang You Co.,Ltd ., Nanjing, China), a total of 9 pieces, with a diameter of 1.2mm and a length of 120mm. figure 1 A schematic diagram of a radiofrequency ablation experimental device according to an embodiment of the present invention is shown, which includes a radiofrequency temperature-controlled ablation apparatus RFA-I and a t...

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Abstract

The invention discloses a biological tissue characteristic parameter representation method based on single-needle actual measurement. The method comprises steps that step 1, through a radio frequencyheat ablation experiment, a power distribution function is acquired; step 2, a preset initial condition and a boundary condition are preset in COMSOL Multiphysics software, and a radio frequency temperature field simulation model is established; step 3, sensitivity analysis on biological tissue characteristic parameters is carried out; step 4, based on the parameter sensitivity analysis result, anaccurate representation function of sensitive parameters is acquired through utilizing single-needle actual measurement data; and step 5, the accurate representation function of the sensitive parameters is utilized to carry out temperature field simulation, comparison with actual measurement data is carried out to verify accuracy of a temperature field distribution model. The method is advantagedin that a problem that temperature field distribution can not be accurately acquired because of uncertainty of biological tissue characteristic parameters in the prior art is solved.

Description

technical field [0001] The invention relates to a biological tissue characteristic parameter characterization method based on single-needle actual measurement, in particular, the accurate characterization form of the biological tissue sensitivity characteristic parameter obtained in the radiofrequency ablation process by using a fitting formula. Background technique [0002] Liver tumors are one of the greatest threats to human life and the second leading cause of death in China. Therefore, effective treatment of liver tumors has become an urgent social problem. At present, radiofrequency thermal ablation technology has been widely used in hospitals due to its advantages of minimal invasiveness and remarkable therapeutic effect, and has become an effective method for treating human liver tumors. However, the quality of thermal ablation still mainly depends on the experience of clinicians. Lack of objective basis. In clinical operations, 54°C is often used as the boundary th...

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Application Information

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IPC IPC(8): G16H50/50G06F17/50
CPCY02E60/00
Inventor 吴水才王笑茹夏秋实高宏建周著黄
Owner BEIJING UNIV OF TECH
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