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Tartaric acid acetylisovaleryltylosin tartrate soluble particle and preparation method thereof

A tylvalosin and soluble technology, which is applied in the field of tylvalosin tartrate soluble granules and its preparation, can solve the problems of poultry and livestock poisoning, uneven mixing, inconvenient mixing, etc., and achieve the effect of uniform drug and remarkable effect

Inactive Publication Date: 2018-02-27
四川维尔康动物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Tivalamectin tartrate soluble powder is only used for chicken drinking water administration according to the standard, and only has a specification of 25g, so this preparation cannot meet the needs of livestock and large-scale breeding groups.
Tivalamectin tartrate premix can only be administered in mixed feeding in clinical use, so the farm also needs to be equipped with a mixer. If it is a large-scale farm, the amount of feed is large every day, and mixing is inconvenient; and , due to the difference in particle size and specific gravity between the premix and the feed, it is likely to cause uneven mixing, which is likely to cause poultry and livestock poisoning

Method used

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  • Tartaric acid acetylisovaleryltylosin tartrate soluble particle and preparation method thereof
  • Tartaric acid acetylisovaleryltylosin tartrate soluble particle and preparation method thereof
  • Tartaric acid acetylisovaleryltylosin tartrate soluble particle and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0023] A kind of tylvalosin tartrate soluble granules, the soluble granule components include medicinal components and auxiliary material components, wherein, the medicinal components are composed of tivalamectin tartrate; the auxiliary materials are composed of binders and fillers, wherein the binders are soluble It is composed of starch and povidone K30, and the filling agent is composed of one or more of lactose, glucose and sucrose.

[0024] The weight percent of each component in the soluble granule is: 5% of tyvalocin tartrate, 1% of soluble starch, 0.5% of povidone K30, and 93.5% of lactose.

Embodiment 2

[0026] A kind of tylvalosin tartrate soluble granules, the soluble granule components include medicinal components and auxiliary material components, wherein, the medicinal components are composed of tivalamectin tartrate; the auxiliary materials are composed of binders and fillers, wherein the binders are soluble It is composed of starch and povidone K30, and the filling agent is composed of one or more of lactose, glucose and sucrose.

[0027] The weight percent of each component in the soluble granule is: 10% of tyvalactin tartrate, 1% of soluble starch, 0.5% of povidone K30, and 88.5% of glucose.

Embodiment 3

[0029] A kind of tylvalosin tartrate soluble granules, the soluble granule components include medicinal components and auxiliary material components, wherein, the medicinal components are composed of tivalamectin tartrate; the auxiliary materials are composed of binders and fillers, wherein the binders are soluble It is composed of starch and povidone K30, and the filling agent is composed of one or more of lactose, glucose and sucrose.

[0030] The weight percent of each component in the soluble granule is: 20% of tyvalactin tartrate, 1% of soluble starch, 0.5% of povidone K30, and 78.5% of sucrose.

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Abstract

The invention discloses a tartaric acid acetylisovaleryltylosin tartrate soluble particle and a preparation method thereof. The soluble particle components consist of a medicinal component and accessory components, wherein the medicinal component is tartaric acid acetylisovaleryltylosin tartrate; the accessory components consist of an adhesive and a filling agent. The invention develops a novel preparation type of the tartaric acid acetylisovaleryltylosin tartrate; the soluble particle can be administrated by drinking water or mixing, is convenient to use and meets the demand of scale breedingindustry; meanwhile, mycoplasma pneumonia of livestock and poultry can be effectively controlled and the effect is remarkable.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, and in particular relates to a soluble granule of tyvalactin tartrate and a preparation process thereof. Background technique [0002] Respiratory diseases of livestock and poultry are famous for their stubbornness and are characterized by "three nos", that is, not dying, not healing, and not growing, which increases the cost of breeding, and respiratory infections caused by mycoplasma are particularly common, which can cause pigs to cough and wheeze, commonly known as asthma Diseases can also cause chickens to cough, runny nose, respiratory rales, and mouth breathing. Once mycoplasma is infected in the farm, it can exist for a long time and is quite stubborn. A survey shows that pig enzootic pneumonia (asthma) leads to an average daily weight loss of 17%, and an average feed utilization rate of 14%. Respiratory system disease (especially chronic respiratory system disease) is one of the impor...

Claims

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Application Information

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IPC IPC(8): A61K9/16A61K31/7048A61K47/36A61K47/32A61K47/26A61P11/00A61P31/04
CPCA61K9/1652A61K9/1623A61K9/1635A61K31/7048
Inventor 张槐陶勇黄玉伟张纯林陈强黄声全卢朝华
Owner 四川维尔康动物药业有限公司