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Sustained-release pellet for weed inhibitor and preparation method thereof

A technology of inhibitors and pellets, applied in botany equipment and methods, herbicides and algicides, biocides, etc., can solve the adverse effects of product quality, consumption safety, high economic and labor costs, and the availability of active ingredients Low-level problems, to achieve the effect of facilitating large-scale industrial production, reducing the number of pesticides, and suppressing weeds

Inactive Publication Date: 2014-08-20
安庆缘启医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, traditional dosage forms are mainly used in domestic agriculture: such as powders, wettable powders, emulsions, dispersions, etc. During application, the purpose is achieved through multiple dosages, the utilization of active ingredients is low, the dosage is large, and the economic and labor costs are high. It not only causes a lot of waste, but also causes environmental pollution and excessive pesticide residues in crop products, which directly affects product quality and its consumption safety.

Method used

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  • Sustained-release pellet for weed inhibitor and preparation method thereof
  • Sustained-release pellet for weed inhibitor and preparation method thereof
  • Sustained-release pellet for weed inhibitor and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] The formulation of weed inhibitor sustained and controlled release pellets is as follows:

[0058] Promethazine: Borax (4:1) = 64g : 16 g 40%

[0059] Microcrystalline Cellulose: 80g 40%

[0060] Ethyl cellulose: 20g 10%

[0061] PEG 6000: 10g 5%

[0062] Sodium Lauryl Sulfate: 10g 5%.

[0063] The preparation process is as follows:

[0064] 1. Mixing of the main drug and auxiliary materials: After mixing the raw materials proteon and borax in proportion, add ethyl cellulose and microcrystalline cellulose, and crush them through an 80-mesh sieve; 2. Making soft materials: add the mixed materials to a certain amount 5% ethanol solution of ethyl cellulose (EC) is used as a binder to make a soft material, which is passed through a 16-mesh sieve to obtain wet granules. 3. Soft material extrusion: put the wet granules into the extruder and press the extrusion aperture mm; Extrusion frequency 20, blowing frequency 50, extruded into strips; 4. Spheronization: put the extrud...

Embodiment 2

[0067] Promethazine: Borax (4:1) = 64g : 16 g 40%

[0068] Microcrystalline Cellulose: 60g 30%

[0069] Ethyl cellulose: 40g 20%

[0070] PEG 6000: 10g 5%

[0071] Sodium dodecyl sulfonate: 10g 5%

[0072] The preparation steps are as follows: 1. Main ingredient and auxiliary material mixing: After mixing the raw material promethazine and borax in proportion, adding ethyl cellulose, microcrystalline cellulose, pulverizing through 80 mesh sieve; 2. Making soft material: mixing Add a certain amount of 5% ethanol solution of ethyl cellulose to the material as a binder to make a soft material, and pass through a 16-mesh sieve to obtain wet granules. 3. Soft material extrusion: Put the wet granules into the extruder according to the extrusion aperture 1.5 mm; Extrusion frequency 20, blowing frequency 50, extruded into strips; 4. Spheronization: put the extruded product into the spheronizer for spheronization, the spheronization speed is 800 rpm, and take out the pellets after 10...

Embodiment 3

[0074] Promethazine: Borax (4:1)=64g: 16 g 40%

[0075] Microcrystalline Cellulose: 40g 20%

[0076] Ethyl cellulose: 60g 30%

[0077] PEG 6000: 10g 5%

[0078] Sodium dodecyl sulfonate: 10g 5%

[0079] The preparation steps are as follows: 1. Main ingredient and auxiliary material mixing: After mixing the raw material promethazine and borax in proportion, adding ethyl cellulose, microcrystalline cellulose, pulverizing through 80 mesh sieve; 2. Making soft material: mixing Add a certain amount of 5% ethanol solution of ethyl cellulose to the material as a binder to make a soft material, and pass through a 16-mesh sieve to obtain wet granules. 3. Soft material extrusion: Put the wet granules into the extruder according to the extrusion aperture 1.5 mm; Extrusion frequency 20, blowing frequency 50, extruded into strips; 4. Spheronization: put the extruded product into the spheronizer for spheronization, the spheronization speed is 800 rpm, and take out the pellets after 10 mi...

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Abstract

The invention discloses a sustained-release pellet for a weed inhibitor. The sustained-release pellet for the weed inhibitor is prepared from an effective ingredient, a sustained-release material, a thinner, a binder, an inert ingredient and a surface active agent. The sustained-release pellet for the weed inhibitor has the beneficial effects of long action time, good weed inhibition effect, small dosage, low toxicity, and small pollution to the environment. The invention also discloses a preparation method for the sustained-release pellet for the weed inhibitor. The method is simple and feasible, and convenient for industrial mass production.

Description

technical field [0001] The invention relates to the field of herbicides, in particular to a sustained and controlled release pellet of weed inhibitors. Background technique [0002] In the late 19th century, it was discovered that copper sulfate, an inorganic compound, could kill some broad-leaved weeds in wheat fields. Since the invention of the first herbicide 2,4-dichlorophenylacetic acid (2,4-D) in the 1940s, world agriculture has entered a new era. In the era of organic compound herbicides, various organic herbicides have come out and developed rapidly for decades, and are widely used in various crop fields and places. The use of herbicides has made great achievements in the fight against weed damage. It not only saves a lot of heavy manual labor and mechanical weeding operations, but also reduces and restores the huge economic and social benefits caused by weed damage. [0003] At present, traditional dosage forms are mainly used in domestic agriculture: such as powde...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N25/34A01N43/70A01N47/36A01P13/00
Inventor 米莉莉张永亮
Owner 安庆缘启医药科技有限公司