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Myocyte differentiation-promoting composition containing amino acids

A technology for muscle cells and compositions, applied in the field of compositions for promoting muscle cell differentiation, can solve problems such as differences

Pending Publication Date: 2018-05-11
AMOREPACIFIC CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, the mechanism related to mTOR signal transmission only shows the effect of strengthening muscle by increasing protein synthesis in muscle, which is related to the differentiation of myoblasts into myocytes to increase the number of myocytes itself, thereby fundamentally restoring the already existing muscle cells. Mechanisms of reduced or lost muscle mass vary

Method used

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  • Myocyte differentiation-promoting composition containing amino acids
  • Myocyte differentiation-promoting composition containing amino acids
  • Myocyte differentiation-promoting composition containing amino acids

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 3

[0084] Example 3................................50mg

[0085] Corn starch................................100mg

[0086] Lactose................................................100mg

[0087] Magnesium stearate................................2mg

[0088] Vitamin C...................................50mg

[0089] Tablets are prepared by mixing the ingredients and then compressing them in the usual way for tablet preparation.

[0090] [Dosage Form Example 2] Preparation of Capsules

[0091] Example 3................................50mg

[0092] Corn starch................................100mg

[0093] Lactose................................................100mg

[0094] Magnesium stearate................................2mg

[0095] Vitamin C...................................50mg

[0096] Serine................................................50mg

[0097] Capsules are prepared by mixing the ingredients and filling gelatin capsules in the usual way for capsules.

[0098] [...

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PUM

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Abstract

The present invention relates to a myocyte differentiation-promoting composition containing amino acids, and more specifically, to a myocyte differentiation promoter formed of phenylalanine and methionine, a pharmaceutical composition containing same for preventing or treating senile muscle loss, and a functional health food composition containing same for preventing or improving senile muscle loss. The myocyte differentiation-promoting composition and the pharmaceutical composition or the functional health food composition containing same of the present invention promote the differentiation of a myoblast into a muscle cell, thereby enabling the prevention, improvement and treatment of sarcopenia or muscle loss, and are especially effective for senile muscle loss, and have the effect of oxidizing fatty acid in vivo by means of an increase in the basal metabolic rate in accordance with an increase in the number of myocytes.

Description

technical field [0001] The present invention relates to a composition for promoting muscle cell differentiation containing amino acids, and more specifically, to a muscle cell differentiation promoting agent composed of phenylalanine and methionine, and a composition for preventing or treating senile muscle loss containing the same. A pharmaceutical composition and a health functional food composition for preventing or improving senile muscle loss. Background technique [0002] The muscles of our body are attached to the bones and have multiple functions such as protecting the bones and maintaining body shape. In addition, muscle can also promote calcium influx and improve bone density. However, as the body ages, the composition changes, which causes the redistribution of body fat and body protein. At about 50 years old, the synthesis rate of protein in muscle cells is slower than the decomposition rate, so that the muscle begins to degenerate rapidly, and Exposure to sarc...

Claims

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Application Information

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IPC IPC(8): A61K31/198
CPCA61K31/198
Inventor 郑炫禹罗赞洙孙钟熙金完起申松锡
Owner AMOREPACIFIC CORP
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