Novel application of traditional Chinese medicine preparation as medicine for treating osteoarthritis

A technology of osteoarthritis and traditional Chinese medicine preparations, which is applied in the field of new drug applications, and can solve the problems of patient inconvenience and susceptibility to infection

Active Publication Date: 2018-05-18
GUANGXI YINGKANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage is that a complete aseptic operation must be performed by a specialized orthopedic surgeon, otherwise infection will easily occur; at this stage, many to...

Method used

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  • Novel application of traditional Chinese medicine preparation as medicine for treating osteoarthritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The Chinese medicinal preparation prepared by the following manufacturing process steps can treat rheumatoid arthritis, rheumatoid arthritis, and frozen shoulder, but also treat osteoarthritis:

[0030] (1) Take 700 parts of red fish eye, 700 parts of nine-layer wind, 450 parts of three-leaf green vine, 450 parts of mountain wind, 160 parts of two-faced needles, 25 parts of panax notoginseng stems and leaves according to weight, and crush them into coarse powder. ~10 mesh sieve, spare;

[0031] (2) Place the coarse powder in an extraction tank, add 50-70% ethanol with a volume concentration of 50% to 70%, and extract 3 times at 2 hours each time. The extract is filtered through a 180-200 mesh sieve to obtain the filtrate; the coarse powder is calculated by weight, The volume concentration is 50~70% ethanol by volume, coarse powder: the volume concentration is 50~70% ethanol=1: (4~6);

[0032] (3) Use a vacuum device to recover ethanol from the filtrate and concentrate it to a...

Embodiment 2

[0036] The Chinese medicinal preparation prepared by the following manufacturing process steps can treat rheumatoid arthritis, rheumatoid arthritis, and frozen shoulder, but also treat osteoarthritis:

[0037] (1) Take 846.7 parts of red fish eyes, 846.7 parts of nine-layer wind, 564.5 parts of three-leaf green vine, 564.5 parts of mountain wind, 170.9 parts of fennel needle, 28.2 parts of panax notoginseng stems and leaves according to weight, and crush them into coarse powder, over 8 ~10 mesh sieve, spare;

[0038] (2) Place the coarse powder in an extraction tank, add 50-70% ethanol with a volume concentration of 50% to 70%, and extract 3 times at 2 hours each time. The extract is filtered through a 180-200 mesh sieve to obtain the filtrate; the coarse powder is calculated by weight, The volume concentration is 50~70% ethanol by volume, coarse powder: the volume concentration is 50~70% ethanol=1: (4~6);

[0039] (3) Use a vacuum device to recover ethanol from the filtrate and con...

Embodiment 3

[0043] The Chinese medicinal preparation prepared by the following manufacturing process steps can treat rheumatoid arthritis, rheumatoid arthritis, and frozen shoulder, while also curing osteoarthritis:

[0044] (1) Take 846.7 parts of red fish eye, 846.7 parts of nine-layer wind, 564.5 parts of trifoliate vine, 564.5 parts of Dafeng wormwood, 170.9 parts of fennel needle, 28.2 parts of Panax notoginseng stems and leaves by weight, and crush them into coarse powder, over 8 ~10 mesh sieve, spare;

[0045] (2) Place the coarse powder in an extraction tank, add 60% ethanol with a volume concentration, and extract 3 times at reflux for 2 hours each time. The extract is filtered through a 180-200 mesh sieve to obtain the filtrate; the coarse powder is by weight and volume concentration For 50~70% ethanol by volume, coarse powder: volume concentration of 50~70% ethanol=1: (4~6);

[0046] (3) Use a vacuum device to recover ethanol from the filtrate and concentrate it to an extract with a ...

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PUM

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Abstract

The invention provides novel application of a traditional Chinese medicine preparation as a medicine for treating osteoarthritis. Osteoarthritis has the following clinical symptoms: denatured damage of cartilago articularis, sclerosis or cystic degeneration of subchondral bones, joint edge hyperostosis, synovial hyperplasia, capsular contracture, ligamentous laxity or contracture, muscular dystrophy and the like. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 700-1,100 parts of phyllanthus reticulata, 700-1,100 parts of radix cyathulae, 450-800 parts of illigera trifoliata, 450-800 parts of radix et caulis fissistigmae, 160-320 parts of radix zanthoxyli and 25-40 parts of panax notoginseng stalks and leaves, wherein radix et caulis fissistigmae can be replaced with herba blumeae balsamiferae in the same parts. The medicine which is originally used for treating rheumatic arthritis, scapulohumeral periarthritis and chronic infectious arthritis is used for treating osteoarthritis. The curative effect in treating osteoarthritis is remarkable, adaptation diseases of the original medicine are expanded, and a novel medicine for treating osteoarthritis is provided for clinical treatment.

Description

Technical field [0001] The invention belongs to the technical field of new uses of medicines, in particular to a new use of a traditional Chinese medicine preparation as a medicine for treating osteoarthritis. technical background [0002] Huatuo Fengtongbao Tablets (originally named "Fengshiling Tablets") is a traditional Chinese medicine preparation. It was produced by Guangxi Baiyunshan Yingkang Pharmaceutical Co., Ltd. (formerly known as Guangxi Yingkang Pharmaceutical Co., Ltd., formerly known as Guangxi The current standard of the drugs produced by the Pharmaceutical School of Pharmaceutical Sciences is the national drug standard YBZ01972008. The product has won the third prize of Guangxi Science and Technology Progress Award, the second prize of Guangxi Medicine and Health Science and Technology Progress Award, and has been listed as a national second-class Chinese medicine protection product. [0003] Huatuo Fengtongbao tablets have been favored by patients since they were ...

Claims

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Application Information

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IPC IPC(8): A61K36/758A61P19/02A61P29/00A61P21/00A61P19/04
CPCA61K36/185A61K36/21A61K36/258A61K36/28A61K36/47A61K36/758A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 程宏辉梁峰黄平权黄若干蓝晓东梁杰敏
Owner GUANGXI YINGKANG PHARMA
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