Unlock instant, AI-driven research and patent intelligence for your innovation.

Red yeast rice traditional Chinese medicine water infusion decoction piece

A technology of red yeast rice and traditional Chinese medicine, applied in the field of medicine, can solve the problems of difficult dissolution of active ingredients, complex chemical components, and different quality

Pending Publication Date: 2018-06-05
江苏苏轩堂药业有限公司
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, because the chemical components contained in each herb are very complex, and the quality varies from place to place, the content quality requirements are often based on the content of its index components or active components reaching a certain value (except for toxic components), plus Most of the active ingredients are stored in their cells, and the active ingredients are not easy to dissolve, etc. So far, there is no comprehensive scientific data for a comprehensive evaluation of its quality, including its stability (validity period)

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Red yeast rice traditional Chinese medicine water infusion decoction piece
  • Red yeast rice traditional Chinese medicine water infusion decoction piece
  • Red yeast rice traditional Chinese medicine water infusion decoction piece

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0038] Preparation of reference substance solution Take an appropriate amount of lovastatin reference substance, accurately weigh it, add 75% acetone solution to make a solution containing 0.04mg per 1ml, and use it as lovastatin reference substance solution.

[0039] Preparation of the test solution Take this product, grind it finely, take about 0.78g, accurately weigh it, put it in a stoppered Erlenmeyer flask, add 25ml of 75% acetone solution accurately, weigh it, and make up the lost amount with 75% acetone solution. weight, shake well, filter, and take the filtrate, that is.

[0040] Determination method Precisely draw 5-10μl each of the above-mentioned lovastatin reference solution and the test solution, inject it into the liquid chromatograph, measure it, and obtain it.

[0041] The product is calculated as a dry product, and every 1g contains lovastatin (C 24 h 36 o 5 ), not less than 0.30mg.

[0042] Microbial limit inspection According to the microbial limit stan...

Embodiment 1

[0054] 160 kilograms of red yeast rice were divided into 3 experimental batches (60 kilograms per batch). According to the GMP standard of medicines, impurities were removed, dried, packaged (clean area), and sterilized to make small-package red yeast rice finished products.

[0055] (1) Comparison experiment of water decoction (100°C) and hot water (80-90°C) water immersion:

[0056] The product of the present invention is based on the comparison experiment of water decoction (100°C) and hot water (80-90°C) water immersion of red yeast rice, taking the total amount of lovastatin in the water extract as an index, comparing red yeast rice by electronic There may be differences in the indicators of water decoction and hot water brewing after beam irradiation sterilization.

[0057] Through the above experimental research (see Table 1-2, figure 1 ), the results of the present invention show that the total amount of lovastatin in the hot water (80-90°C) soaked extract of the "red...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
Login to View More

Abstract

The invention provides a red yeast rice traditional Chinese medicine water infusion decoction piece. A preparation process comprises the following steps of (1) removing impurities from red yeast rice;after clean preparation, performing drying to obtain an intermediate; (2) inspecting the intermediate; after the packaging, performing electron beam irradiation sterilization; (3) performing standardinspection; obtaining a finished product after the packaging, wherein in the step (2), the irradiation dose of the electron beam irradiation sterilization is 3 to 10 kGy; in the step (3), the inner packaging is performed in a D stage clean region. Through the modern natural medicine analysis measure and traditional Chinese medicine pharmacy process, the conventional traditional Chinese medicine decoction piece red yeast rice is prepared into the red yeast rice traditional Chinese medicine water infusion decoction piece which conforms to the current national relevant medicine laws and regulations, Jiangsu Province Traditional Chinese Medicine Decoction Piece Processing Specification version in 2002, Chinese Pharmacopoeia version in 2015 four-part standard, does not need decoration or boiling and can be taken after boiling water infusion.

Description

technical field [0001] The invention relates to a red yeast rice traditional Chinese medicine soaked decoction piece, which belongs to the technical field of medicine. Background technique [0002] Red yeast rice, the name of traditional Chinese medicine, is called red rice among the people. It is made of rice such as indica rice, japonica rice, and glutinous rice, fermented with Monascus, and it is brown-red or purple-red rice grains. Its nature and flavor: sweet, warm, has the effect of invigorating the spleen and eliminating food, promoting blood circulation and removing stasis, and is mainly used for postpartum lochia, stagnant abdominal pain, fullness due to food accumulation, red and white diarrhea, and traumatic injuries. Red Yeast Rice is listed in the 2002 edition of the "Jiangsu Provincial Standards for the Processing of Chinese Herbal Pieces" as a Chinese medicine for blood lipid-lowering and gynecological medicine. [0003] The main functional components in red ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K36/062A61P15/00A61P29/00A61P1/14A61P1/12A61P3/06A61P9/00A61P9/12A61P3/10A61P35/00A61P39/00A61P19/10A61P37/04A61P9/10A61P9/08A61L2/08A61K131/00
CPCA61K9/0095A61K36/062A61K36/899A61K2236/13A61K2236/17A61K2236/19A61L2/007A61L2202/21
Inventor 邓京振周建平
Owner 江苏苏轩堂药业有限公司