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A kind of detumescence medicine for external application and application thereof

A technology of external application medicine, iohexol, which is applied in the field of detumescence medicine, can solve the problems of difficult detumescence, strong viscosity, high crystal osmotic pressure, etc., and achieve the goal of low drug price, rapid detumescence and pain relief, and prevention of phlebitis Effect

Active Publication Date: 2020-08-18
赣南医学院第一附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And because iohexol is a hyperosmotic drug with strong viscosity, apply magnesium sulfate wet compress, the penetration of magnesium ions, the osmotic pressure of crystals in the local tissue is higher, so that the blood plasma and intracellular water in the blood vessel enter the tissue Gaps, more difficult to deswell

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The medicine for external application is mixed with 75% ethanol of 50g yellow gardenia (fine powder), 50g flour and 90ml.

[0019] Xu ×, male, 54 years old, rectal cancer, after enhanced abdominal CT, the drug extravasation grade was grade Ⅳ. After using the external application medicine of embodiment 1 for three times for 8 hours, the swelling disappeared completely, and the limb temperature and color were normal without pain.

Embodiment 2

[0021] The medicine for external application is mixed with 75% ethanol of 40g yellow gardenia (fine powder), 40g flour and 70ml.

[0022] Zhang XX, female, 56 years old, had left breast cancer. After enhanced chest CT, the drug extravasation grade was grade Ⅳ. After using the external application medicine of embodiment 2 for four times for 12 hours, the swelling completely subsided, and the body temperature and color were normal without pain, and the finger activities were normal, and the blisters were incrusted.

Embodiment 3

[0024] The medicine for external application is mixed with 75% ethanol of 20g yellow gardenia (fine powder), 20g flour and 30ml.

[0025] Li XX, male, 79 years old, suffered from abdominal pain. After enhanced CT of the abdomen, the drug extravasation grade was grade Ⅱ. After using the external application medicine of embodiment 3 once for 3 hours, the swelling disappeared completely, and the body temperature and color were normal without pain. Once cured, no further treatment is required.

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Abstract

The invention relates to a detumescence medical care technology after iohexol injection in enhanced CT, in particular relates to detumescence medicine for external application and application thereof.The medicine for external application is prepared from 10 to 50g of powdery fructus gardeniae jasminoides, 10 to 60g of flour and 15 to 100ml of 50 to 75 percent ethanol through being mixed. The medicine for external application has the obvious curative effect on iohexol drug exosmosis, and can achieve the effects of fast detumescence and pain relief; the detumescence time is within 14h; the skintemperature of affected area fast lowers down; the patient care time is shortened; the occurrence of complications such as phlebitis can be prevented; the work efficiency and the satisfaction degreeof the patient are improved; meanwhile, the medicine price is low; the treatment cost is reduced for patients.

Description

technical field [0001] The invention relates to a medical technology for detumescence after injection of iohexol in enhanced CT, in particular to a detumescence externally applied medicine and application thereof. Background technique [0002] In enhanced CT, iohexol injection was used as the contrast agent, and the high-pressure syringe was used to inject the drug. The dose was large and the injection speed was fast. The injection time of 100ml iohexol was 20-40s. Despite many precautions, the rate of extravasation of iohexol in clinical practice is high. Over the years, local external application of 30-50% magnesium sulfate or magnesium sulfate powder + dexamethasone or Jinhuang powder + magnesium sulfate or potato chips has been used for the swelling of iohexol extravasation. The curative effect is very slow, and the swelling time is more than 24 hours. And because iohexol is a hyperosmotic drug with strong viscosity, apply magnesium sulfate wet compress, the penetration...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P29/00
CPCA61K9/0014A61K36/185A61K36/744A61K36/899A61P29/00A61K2300/00
Inventor 叶新英吴莲香谢红英
Owner 赣南医学院第一附属医院
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