High-strength gradient full-absorption artificial ligament and preparation method thereof

Abstract

The invention discloses a high-strength gradient full-absorption artificial ligament and a preparation method of the high-strength gradient full-absorption artificial ligament. The artificial ligamentcomprises an articular cavity free section and marrow channel woven sections at the two ends of the articular cavity free section, wherein the marrow channel woven sections are of sheath-core double-layer tube-shaped structures, and the sheath-core double-layer tube-shaped structures are composed of sheath layers and core layers. The preparation method comprises the following step: preparing themarrow channel woven sections of the sheath-core double-layer tube-shaped structures by adopting a weaving, knitting or braiding integrated forming technology, wherein weft yarns are not arranged at the articular cavity free section, namely, parallel free yarns not participating in weaving are adopted. The adopted yarns are formed by twisting and compounding fibers with different degrading periodsat the specific ratio, after implantation, a three-dimensional spiral through porous channel can be constructed through gradient degrading, thus the oriented growth of host cells is induced, and meanwhile, the requirement for the mechanical property needed during the tendon-bone healing process is met.

Description

technical field

[0001] The invention relates to a high-strength gradient fully-absorbable artificial ligament for treating anterior cruciate ligament injuries and a preparation method thereof, especially a high-strength gradient fully-absorbable artificial ligament prepared by integral molding technology, which belongs to biomedical textiles Preparation technology field. Background technique

[0002] The anterior cruciate ligament is located in the knee joint, connecting the femur and tibia, and is an important structure to maintain the stability of the knee joint. Due to its special structure and location, it is easily damaged in daily activities and sports, and its self-healing ability is poor, which affects joint performance. At present, the main method for clinical treatment of ligament injury is surgical reconstruction, and commonly used grafts include autologous tendon, allogeneic tendon and artificial ligament. Among them, autologous transplantation has no immune re...

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