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Integrated plasma separation hemoperfusion apparatus

A hemoperfusion device and plasma separation technology, which is applied in the field of integrated plasma separation hemoperfusion device, can solve the problems of incomplete use of adsorbent, increase of patient treatment cost, and inability to achieve adsorption, etc., to achieve direct contact improvement, reduction of treatment cost, The effect of reducing the cost of consumables

Inactive Publication Date: 2018-08-24
WUHAN RUIFA MEDICAL DEVICES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing adsorbers cannot realize the cycle mode of "adsorption-regeneration-adsorption".
[0010] In addition, it should be pointed out that the adsorber disclosed in the patent with the publication number of CN 102631722 B is not partitioned, resulting in uneven adsorption of the fibrous adsorbent in the shell, resulting in unsatisfactory actual adsorption effect. Incomplete use of doses further increases patient treatment costs

Method used

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  • Integrated plasma separation hemoperfusion apparatus
  • Integrated plasma separation hemoperfusion apparatus
  • Integrated plasma separation hemoperfusion apparatus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Such as figure 1 The one-piece blood plasma separation hemoperfusion device shown includes a housing 1, a blood inlet 2, a blood outlet 3, and a plasma outlet 4 that are arranged on the housing 1 and communicate with the interior thereof. The inner cavity of the housing 1 is provided with a separation chamber 5 and the adsorption chamber 6; the two ends of the inner cavity of the housing 1 are provided with a sealing ring 7; the separation chamber 5 is provided with a hollow fiber membrane 8; the two ends of the hollow fiber membrane 8 are inserted and fixed on the sealing ring 7 and communicate with the blood inlet 2 and The blood outlet 3; the separation chamber 5 and the adsorption chamber 6 communicate through the first porous membrane 9 that only allows blood plasma to pass through; the adsorption chamber 6 is provided with a microsphere-shaped adsorption resin 10; The casing 1 is also provided with a sample injection port 11 communicating with the adsorption chamb...

Embodiment 2

[0032] Such as Figure 2~4The one-piece blood plasma separation blood perfusion device shown in this embodiment has the same main features as that of Embodiment 1, and the difference is that: there is also an adsorption chamber 6 that divides the adsorption chamber 6 into a first adsorption chamber 14 and a second adsorption chamber. 15, the second porous membrane 16 that only allows the plasma in the blood to pass through, the second porous membrane 16 can allow the regeneration liquid 13 to pass through; "Indicates that only plasma is permeable in blood, and not only plasma is permeable in all substances (blood and others); the first adsorption chamber 14 communicates with the separation chamber through the first porous membrane 9; the first adsorption chamber 14 A plurality of non-porous membranes 19 are provided inside to separate it into a plurality of independent cavities 17, and each cavity 17 is provided with a wavy linear adsorbent attachment film 18; the adsorbent at...

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Abstract

The invention discloses an integrated plasma separation hemoperfusion apparatus, which comprises a shell, as well as a blood inlet, a blood outlet and a plasma outlet which are formed in the shell andcommunicate with the interior of the shell, wherein a separating compartment and an adsorption cavity are formed in an inner cavity of the shell; seal rings are arranged at two ends of the inner cavity of the shell; a hollow fiber film is arranged in the separation compartment; two ends of the hollow fiber film are flexibly inserted into the seal rings and communicate with the blood inlet and theblood outlet; the separation compartment and the adsorption compartment get communicated via a first porous film which just permits penetration of plasmid; and micro-spheric adsorption resin is arranged in the adsorption compartment. The integrated plasma separation hemoperfusion apparatus provided by the invention has the beneficial effects that plasma separation and plasma adsorption can be simultaneously implemented by arranging the separation compartment and the adsorption compartment, so that direct contact between hemocyte and an adsorbent is avoided, and subsequently, biocompatibilityis improved; a regenerative therapy mode or a single-adsorption therapy mode can independently selected in accordance with patient's disease condition; consumable cost and treatment cost are reduced;and an adsorption effect is enhanced.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to an integrated blood plasma separation hemoperfusion device. Background technique [0002] Hemodialysis is one of the renal replacement therapies for patients with acute and chronic renal failure. It drains the blood from the body to the outside of the body through a dialyzer composed of hollow fibers. The blood and the electrolyte solution (dialysate) with a similar concentration to the body are inside and outside a hollow fiber, and exchange substances through diffusion / convection to remove the toxins in the body. The whole process of metabolizing waste, maintaining electrolyte and acid-base balance; removing excess water from the body, and reinfusing purified blood is called hemodialysis. [0003] Hemoperfusion mainly uses adsorbents to remove toxins and pathogenic substances in the blood, so as to achieve the purpose of purifying the blood, relieving and treating diseases. Hem...

Claims

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Application Information

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IPC IPC(8): A61M1/16A61M1/36
CPCA61M1/1621A61M1/3621A61M1/3679A61M2202/0415A61M2202/049A61M2202/0021A61M2202/0057
Inventor 张磊王业富胡定邦张媛温佳文何改粉韩玮
Owner WUHAN RUIFA MEDICAL DEVICES CO LTD
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