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2 results about "Hemocyte" patented technology
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A hemocyte is a cell that plays a role in the immune system of invertebrates. It is found within the hemolymph. Hemocytes are phagocytes of invertebrates. Hemocytes in Drosophila melanogaster can be divided into two categories: embryonic and larval. Embryonic hemocytes are derived from head mesoderm and enter the hemolymph as circulating cells. Larval hemocytes, on the other hand, are responsible for tissue remodeling during development. Specifically, they are released during the pupa stage in order to prepare the fly for the transition into an adult and the massive associated tissue reorganization that must occur. There are four basic types of hemocytes found in fruit flies: secretory, plasmatocytes, crystal cells, and lamellocytes. Secretory cells are never released into the hemolymph and instead send out signalling molecules responsible for cell differentiation. Plasmatocytes are the hemocytes responsible for cell ingestion and represent about 95% of circulating hemocytes.
Construction method of congenital pure red cell anemia zebra fish model
The application relates to a method for constructing a congenital pure red cell anemia zebra fish model, which comprises the following steps: performing directional mutation on a bysl gene in a wild-type zebra fish embryo to obtain F0 generation zebra fish; mating the F0 generation zebra fish with wild-type zebra fish to screen positive heterozygote F1 generation zebra fish from born zebra fish; mating the positive heterozygote F1 generation zebra fish with wild-type zebra fish to screen positive heterozygote F2 generation zebra fish from born zebra fish; and mating the positive heterozygote F2 generation zebra fish to screen positive homozygote zebra fish from born zebra fish as a congenital pure red cell anemia zebra fish model. The model can simulate the symptoms of congenital pure red cell anemia, and can be used for mechanism research, drug evaluation and new drug screening of the disease.
Owner:AFFILIATED HOSPITAL OF GUANGDONG MEDICAL UNIV
A fluorescence in situ hybridization method for co-localization of multiple genes in hemocytes of bivalves
PendingCN122081511AMaterial analysis by observing effect on chemical indicatorClimate change adaptationMarine invertebratesVertebrate Animals
The present invention discloses a fluorescence in situ hybridization method for co-localization of multiple genes in shellfish hemocytes, belonging to the technical field of cell biology of marine invertebrates. By optimizing the osmotic pressure buffer system and the preparation method, the present invention can stably obtain a monolayer sample with complete and uniform cell morphology. By advancing the cell morphology imaging step, the complete morphological information of cells is obtained and fixed as a reference before implementing the stringent in situ hybridization process. The present invention can achieve in situ visualization of multiple target genes while better preserving the cell morphological structure, which helps to obtain more accurate and stable spatial distribution information of gene expression at the single-cell level, improves the overall reliability of the experiment, and provides a more effective analysis tool for the study of cell functions of marine invertebrates.
Owner:OCEAN UNIV OF CHINA +1