Radix paeoniae rubra terpene glycoside composition with function of anti-myocardial ischemia and preparation method thereof
A technology of anti-myocardial ischemia and paeonolin, which is applied in the direction of medical preparations containing active ingredients, drug combinations, cardiovascular system diseases, etc., can solve unfavorable research and application, unfavorable anti-myocardial ischemia, and insufficient material basis clarification and other issues
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[0024] Example 1 Injection
[0025] The red paeoniflorin composition in this embodiment includes: paeoniflorin 50.0% by weight, paeoniflorin 25.0% by weight, benzoylpaeoniflorin 15.0% by weight, and oxypaeoniflorin 10.0% by weight.
[0026] Dissolve a selected amount of the above-mentioned peony terpene glycoside composition with water for injection, slowly add sodium bicarbonate in portions with constant stirring, and when there are no bubbles on the liquid surface, add sodium metabisulfite to dissolve, add water for injection to the full amount; then use pH acidity The pH value of the medicinal solution measured by the meter should be 5.5-8.0. If it is not in this range, it can be adjusted with sodium bisulfate; the obtained medicinal solution is filtered with a vertical melting glass filter until it is clear, and the ampoule is filled and sealed at 100℃, 30 Sterilize in minutes and get ready.
Example Embodiment
[0027] Example 2 Capsules
[0028] The red peony terpene glycoside composition of this embodiment includes: paeoniflorin 50.0% by weight, paeoniflorin 5.0% by weight, benzoylpaeoniflorin 30.0% by weight, and oxypaeoniflorin 15.0% by weight.
[0029] The selected amount of the above-mentioned peony terpene glycoside composition is mixed with an appropriate amount of starch to form granules, dried, mixed uniformly, and filled into capsules to obtain capsules.
Example Embodiment
[0030] Example 3 Capsules
[0031] The red peony terpene glycoside composition of this embodiment includes: paeoniflorin 50.0% by weight, paeoniflorin 30.0% by weight, benzoylpaeoniflorin 19.0% by weight, and oxypaeoniflorin 1.0% by weight.
[0032] The selected amount of the above-mentioned red peony terpene glycoside composition is mixed with an appropriate amount of dextrin to prepare granules, dried, mixed uniformly, and filled into capsules to obtain capsules.
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