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Novel material with efficient antibacterial, anti-inflammatory and antiviral effect, and preparation method and application thereof

An antibacterial, anti-inflammatory and anti-viral technology, applied in new anti-viral materials, high-efficiency anti-bacterial and anti-inflammatory, application of new materials, and preparation of new materials, can solve the problems of narrow application range and slow research and development of anti-viral materials, and achieve easy separation. Purification, obvious bactericidal activity, easy availability of raw materials

Inactive Publication Date: 2018-08-28
王和祥
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Compared with the widespread use of antibacterial materials, the development of antiviral materials is relatively slow and the scope of use is relatively narrow

Method used

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  • Novel material with efficient antibacterial, anti-inflammatory and antiviral effect, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1: Preparation of antibacterial, anti-inflammatory and anti-viral new material of oximated curcumin grafted cotton fabric

[0033] 1. Activate the textiles with active groups on the surface after cleaning, specifically:

[0034] According to the method reported in the literature, maleic anhydride polymerization is used to introduce maleic acid repeating units on the surface of the textile, as follows:

[0035] Soak 100g of cotton fabric in an aqueous solution containing 7g of maleic anhydride, 0.3g of ammonium persulfate and 0.5g of sodium hypophosphite. The soaking time is more than 30min. Three dipping and three rolling are performed, and the pass rate is more than 85%. The cotton fabric after padding is pre-baked at 80°C for 5 minutes, then baked at 120-160°C for 2-5 minutes, washed with hot water at 60°C, washed with cold water, and dried.

[0036] 2. Derivatization of Curcumin

[0037]

[0038] Add 3.26g curcumin (10mmol), 1.39g hydroxylamine hydrochlori...

Embodiment 2

[0053] Embodiment two: the preparation of curcumin grafted PCL antibacterial, anti-inflammatory, antiviral fiber material

[0054] PCL fiber (polycaprolactone fiber, polycaprolactone fiber) is a medical artificial synthetic fiber material with a wide range of uses and is non-toxic. It is a synthetic polymer material approved by the US FDA that can be used in the body. Curcumin grafted PCL fiber material has good antiviral efficacy, and its preparation method is briefly described as follows:

[0055] One, prepare the dichloromethane solution of polycaprolactone: 10g polycaprolactone is dissolved in the 80mL dichloromethane and obtain concentration is the polycaprolactone dichloromethane solution of 125mg / ml;

[0056] Two, the dimethyl sulfoxide solution of preparation curcumin: the concentration that dissolves 100mg curcumin in 20mL dimethyl sulfoxide is the curcumin dimethyl sulfoxide solution of 5mg / ml;

[0057] 3. Preparation of oximated curcumin grafted PCL antiviral fiber...

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Abstract

The invention discloses a novel material with efficient antibacterial, anti-inflammatory and antiviral effect. The novel material is prepared by bonding natural active small-molecule compounds with antibacterial, anti-inflammatory and antiviral effect onto a textile with reactive groups on the surface or a synthetic polymer material with reactive groups through a grafting reaction. The invention also discloses a preparation method for the novel material with efficient antibacterial, anti-inflammatory and antiviral effect. The novel material provided by the invention has efficient antibacterial, anti-inflammatory and antiviral effect, is applicable to preparation of protective and wearing facilities such as antiviral masks, filters, purifiers, wipes, sanitary articles and underwear, and provides reliable guarantee for the health of people.

Description

technical field [0001] The present invention relates to the technical field of new materials used in daily life and public health, more specifically, the present invention relates to a new material with high-efficiency antibacterial, anti-inflammation, and anti-virus, and also relates to a new material with high-efficiency anti-bacterial, anti-inflammatory, and anti-virus The preparation method also relates to the application of high-efficiency antibacterial, anti-inflammatory and anti-viral new materials. Background technique [0002] Influenza virus (influenza virus) is a representative species of Orthomyxoviridae (Orthomyxoviridae), referred to as influenza virus, including human influenza virus and animal influenza virus, human influenza virus is divided into A (A), B (B), C (C) ), Ding (D) four categories, are the pathogens of influenza (flu). Among them, the antigenicity of influenza A virus is easy to mutate, causing worldwide pandemics many times. Influenza virus i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D06M15/21D06M13/376A41D13/11A41D19/015D06M101/06D06M101/32
CPCA41D13/1192A41D19/015A41D31/30D06M13/376D06M15/21D06M16/00D06M2101/06D06M2101/32
Inventor 王和祥
Owner 王和祥
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