Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A molecular marker related to chicken beak deformity traits and its application

A molecular marker and deformity technology, which is used in the determination/inspection of microorganisms, biochemical equipment and methods, DNA/RNA fragments, etc., to improve animal welfare, great economic application value and scientific research value, and reduce the probability of beak deformity.

Active Publication Date: 2020-07-28
INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI +1
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the traditional method, individuals with deformed beaks in the brooding period are eliminated through phenotype selection, but there are still individuals with deformed beaks in the next generation of breeding after the phenotype selection

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A molecular marker related to chicken beak deformity traits and its application
  • A molecular marker related to chicken beak deformity traits and its application
  • A molecular marker related to chicken beak deformity traits and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1: Confirmation of the correlation between rs313625170 SNP molecular marker and chicken beak deformity traits

[0021] experiment material:

[0022] A case-control (case-control) experimental design was adopted, that is, it was divided into a chicken beak deformity group and a normal group, and the genotype differences between the two groups were compared to find out the loci related to the chicken beak deformity traits. The population to be tested comes from the Changping Experimental Base of the Beijing Animal Husbandry and Veterinary Research Institute. From the Beijing oil chicken population, 48 beak deformed individuals and 48 normal individuals were selected.

[0023] 1. Detection of SNP molecular markers

[0024] 1. Genomic DNA Extraction

[0025] (1) Collection of blood samples

[0026] Collect 1.0 mL of individual blood samples from test chickens by subwing vein blood sampling method, place them in centrifuge tubes that have been added with 0.2 mL of...

Embodiment 2

[0043] Example 2: Association analysis of individual rs313625170 SNP genotype and chicken beak deformity traits

[0044] experiment material:

[0045] A case-control (case-control) experimental design was adopted, that is, it was divided into a chicken beak deformity group and a normal group, and the genotype differences between the two groups were compared to find out the loci related to the chicken beak deformity traits. The population to be tested comes from the Changping Experimental Base of the Beijing Animal Husbandry and Veterinary Research Institute. From the Beijing oil chicken population, 48 beak deformed individuals and 48 normal individuals with obvious traits were selected.

[0046] 1. Detection of SNP molecular markers

[0047] 1. Genomic DNA Extraction

[0048] (1) Collection of blood samples

[0049] Collect 1.0 mL of individual blood samples from test chickens by subwing vein blood sampling method, place them in centrifuge tubes that have been added with 0....

Embodiment 3

[0077] Example 3: The effect of purifying beak deformity traits of Beijing oil chicken by using the genotype of rs313625170 locus

[0078] experiment material:

[0079] A total of 1249 Beijing oil chicken Y-series family groups hatched from the same batch in Changping Experimental Base of Beijing Animal Husbandry and Veterinary Research Institute were selected, including 206 brooding roosters and 1043 hens.

[0080] 1. Phenotype determination of beak deformity traits

[0081] Before the age of 28 days, the beak traits of the chickens were visually observed, and the individuals with beak deformities were counted. The results are shown in Table 6. The malformation rate of this generation (referred to as G1 generation) was 2.43% in roosters, 1.44% in hens, and 1.60% in mixed male and female populations.

[0082] Table 6 The number and proportion of beak deformities and normal individuals identified by phenotype in G1 before 28 days of age

[0083] character Rooster...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of gene detection and discloses a molecular marker related with a chicken beak distortion property and application thereof. An SNP (Single Nucleotide Polymorphism) molecular marker corresponds to a No. 3 chromosome sense strand 88,472,831 site of chicken reference genome gallus_gallus-5.0 version sequence information published by NCBI (National Center of Biotechnology Information) and a basic group is T or G. The SNP molecular marker is related with the chicken beak distortion property and is a new molecular marker; the chicken beak distortion property is purified through determining a gene type of a chicken to be detected on the SNP site; the occurrence probability of the beak distortion property in the group can be reduced, the animal welfareis improved and the breeding loss is reduced. The molecular marker has very great economic application value and scientific research value.

Description

technical field [0001] The invention belongs to the technical field of gene detection, and in particular relates to a molecular marker related to chicken beak deformities and an application thereof. Background technique [0002] The beak is an important and unique facial organ of birds, which functions as the lips and teeth of mammals. In some poultry breeds, especially local chicken breeds such as Qingyuan Ma chicken, Wenchang chicken, Taihe black chicken, beard chicken and Beijing oil chicken, individuals with beak deformities are often found, and the incidence rate of some groups is as high as 3%. Beak deformity mainly manifests as dislocation of the upper and lower beaks, incomplete occlusion, and a crossed state ( figure 1 ), the crossing angles are different, some are deflected by 1-2 degrees, and some are as high as 70 degrees. The feed intake and drinking water of chickens with deformed beaks are seriously affected, the growth status is poor, the egg production is ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C12Q1/6888C12N15/11
CPCC12Q1/6888C12Q2600/124C12Q2600/156
Inventor 陈继兰孙研研白皓叶建华麻慧
Owner INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com