Prescription and technology of piperacillin sodium and tazobactam sodium for injection

A technology of piperacillin sodium and tazobactam sodium, applied in the field of piperacillin sodium and tazobactam sodium for injection, which can solve the problems of complicated steps, complex production process, poor solution clarity and color, and achieve quality Excellent, simple preparation process steps

Inactive Publication Date: 2018-10-09
JIANGSU HAIHONG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] In the prior art, the production process of piperacillin sodium and tazobactam sodium for injection is relatively complicated, and the steps are complicated. At the same time, the clarity and color of the solution are poor during the production process, which affects the quality of the product. Therefore, we propose a piperacillin sodium for injection. The prescription and technology of cillin sodium and tazobactam sodium are used to solve the above problems

Method used

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  • Prescription and technology of piperacillin sodium and tazobactam sodium for injection
  • Prescription and technology of piperacillin sodium and tazobactam sodium for injection

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Embodiment Construction

[0033] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0034] see figure 1 , the present invention provides a technical solution: a prescription for piperacillin sodium-tazobactam sodium for injection, comprising 1000 parts of piperacillin sodium, 250 parts of tazobactam sodium, 25 parts of activated carbon, an appropriate amount of Sodium bicarbonate, appropriate amount of water for injection to 6000ml.

[0035] Sodium bicarbonate is the pH regulator, the pH value of the liquid medicine before decarburization is...

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Abstract

The invention discloses a prescription of piperacillin sodium and tazobactam sodium for injection, which comprises the following raw materials: 1000 parts of piperacillin sodium, 250 parts of tazobactam sodium, 25 parts of activated carbon, an appropriate amount of sodium hydrogen carbonate, and an appropriate amount of water for injection up to 6000 ml. The invention further discloses a technology of the piperacillin sodium and tazobactam sodium for injection, which comprises the following steps: selecting stainless steel utensils and performing dry heat sterilization treatment for later useafter washing clean; calculating the amount of the raw materials charged according to the ratio in the prescription, and preparing 1000 pieces of the piperacillin sodium and tazobactam sodium for injection, which comprise 1000 g of piperacillin sodium, 250 g of tazobactam sodium and 25 g of activated carbon respectively, according to the specification of 1.25g/piece; and preparing 1000 pieces of the piperacillin sodium and tazobactam sodium for injection, which comprise 2000 g of piperacillin sodium, 500 g of tazobactam sodium and 50 g of activated carbon respectively, according to the specification of 2.5g/piece. The prescription disclosed by the invention and the preparation technology using the prescription are simple in steps, and a higher quality piperacillin sodium tazobactam and sodium product for injection can be produced.

Description

technical field [0001] The invention relates to the technical field of medicine production, in particular to a prescription and a process of piperacillin sodium and tazobactam sodium for injection. Background technique [0002] Piperacillin Sodium-Tazobactam Sodium for Injection is a compound preparation, and its components are piperacillin sodium and tazobactam sodium. It is suitable for Staphylococcus, E. , Klebsiella, Enterobacter, Providence, Pseudomonas caused by sepsis, complicated cystitis, pyelonephritis. [0003] In the prior art, the production process of piperacillin sodium and tazobactam sodium for injection is relatively complicated, and the steps are complicated. At the same time, the clarity and color of the solution are poor during the production process, which affects the quality of the product. Therefore, we propose a piperacillin sodium for injection. The prescription and process of cillin sodium and tazobactam sodium are used to solve the above problems....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/496A61K9/19A61P31/04A61P13/10A61P13/12A61K31/4192
Inventor 许前辉李文凯
Owner JIANGSU HAIHONG PHARMA
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