Viscoelastic agent material with oxidation-reduction characteristic

A viscoelastic and characteristic technology, applied in medical science, surgery, etc., can solve problems such as loss of viscoelastic properties, changes in gel elasticity and viscosity, and destruction of three-dimensional network systems, so as to improve stability, storage and transportation Performance, the effect of improving storage stability

Pending Publication Date: 2018-10-19
EYEBRIGHT MEDICAL TECH BEIJING
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Problems solved by technology

However, the addition of substances with oxidation and/or reduction properties such as glutathione will destroy the three-dimensional network system of the original viscoelastic gel system due to the change of the intermolecular force, causing severe changes in the elasticity and viscosity of the gel. Change, or even cause physical degradation, so that

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  • Viscoelastic agent material with oxidation-reduction characteristic
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  • Viscoelastic agent material with oxidation-reduction characteristic

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Embodiment Construction

[0018] The present invention relates to a viscoelastic agent having oxidative and / or reducing properties, said viscoelastic agent comprising the following components:

[0019] - substances with oxidizing and / or reducing properties,

[0020] - viscoelastic substances,

[0021] - osmotic pressure regulators,

[0022] - pH buffers, and

[0023] - water.

[0024] According to one embodiment of the present invention, wherein the substance having oxidative and / or reducing properties is selected from oxidized glutathione and its salts, reduced glutathione and its salts, and cysteine ​​supply sources containing Sulfur compounds, proteins containing cysteine / cystine, B vitamins and mixtures thereof.

[0025] According to another embodiment of the present invention, wherein the viscoelastic agent further comprises a substance having reducing properties, such as vitamin C or folic acid, which is compatible with the substance having oxidative and / or reducing properties.

[0026] Acco...

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Abstract

The invention discloses a viscoelastic agent material with an oxidation and/or reduction characteristic. The viscoelastic agent material with a function of protecting corneal endothelial cells comprises oxidation substances and/or reduction substances, viscoelastic substances, osmotic pressure regulators, pH buffering agents and water.

Description

technical field [0001] The invention belongs to the technical field of biomedical materials, and in particular relates to a viscoelastic agent with redox properties, particularly a viscoelastic agent material with redox properties suitable for ophthalmology. Background technique [0002] Cataract is the ophthalmological disease with the highest probability of blindness in the world, resulting in a significant reduction in the vision and quality of life of the affected patients. At present, the only effective way to treat cataract is surgery. After years of development, phacoemulsification combined with intraocular lens implantation has become the most commonly used cataract surgery method. As we all know, any operation will cause damage to the body's cells, so viscoelastics are often used as auxiliary materials for ophthalmic surgery to temporarily support the surgical space, protect the tissue from mechanical damage by surgical instruments, and facilitate the smooth impleme...

Claims

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Application Information

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IPC IPC(8): A61L31/00A61L31/14A61L31/04A61L31/16
CPCA61L31/00A61L31/042A61L31/043A61L31/14A61L31/16A61L2300/10A61L2300/404C08L5/08
Inventor 耿慧敏解江冰
Owner EYEBRIGHT MEDICAL TECH BEIJING
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