Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Viscoelastic agent material with oxidation-reduction characteristic

A viscoelastic and characteristic technology, applied in medical science, surgery, etc., can solve problems such as loss of viscoelastic properties, changes in gel elasticity and viscosity, and destruction of three-dimensional network systems, so as to improve stability, storage and transportation Performance, the effect of improving storage stability

Pending Publication Date: 2018-10-19
EYEBRIGHT MEDICAL TECH BEIJING
View PDF7 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the addition of substances with oxidation and / or reduction properties such as glutathione will destroy the three-dimensional network system of the original viscoelastic gel system due to the change of the intermolecular force, causing severe changes in the elasticity and viscosity of the gel. Change, or even cause physical degradation, so that the viscoelastic loses its original properties, thus losing the role that the viscoelastic should play in surgery
This is why substances with oxidative and / or reducing properties suitable for ophthalmic use, such as glutathione, have been used in eye drops and ophthalmic perfusion solutions, but have not been used and reported in ophthalmic viscoelastics

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Viscoelastic agent material with oxidation-reduction characteristic
  • Viscoelastic agent material with oxidation-reduction characteristic
  • Viscoelastic agent material with oxidation-reduction characteristic

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0018] The present invention relates to a viscoelastic agent having oxidative and / or reducing properties, said viscoelastic agent comprising the following components:

[0019] - substances with oxidizing and / or reducing properties,

[0020] - viscoelastic substances,

[0021] - osmotic pressure regulators,

[0022] - pH buffers, and

[0023] - water.

[0024] According to one embodiment of the present invention, wherein the substance having oxidative and / or reducing properties is selected from oxidized glutathione and its salts, reduced glutathione and its salts, and cysteine ​​supply sources containing Sulfur compounds, proteins containing cysteine / cystine, B vitamins and mixtures thereof.

[0025] According to another embodiment of the present invention, wherein the viscoelastic agent further comprises a substance having reducing properties, such as vitamin C or folic acid, which is compatible with the substance having oxidative and / or reducing properties.

[0026] Acco...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a viscoelastic agent material with an oxidation and / or reduction characteristic. The viscoelastic agent material with a function of protecting corneal endothelial cells comprises oxidation substances and / or reduction substances, viscoelastic substances, osmotic pressure regulators, pH buffering agents and water.

Description

technical field [0001] The invention belongs to the technical field of biomedical materials, and in particular relates to a viscoelastic agent with redox properties, particularly a viscoelastic agent material with redox properties suitable for ophthalmology. Background technique [0002] Cataract is the ophthalmological disease with the highest probability of blindness in the world, resulting in a significant reduction in the vision and quality of life of the affected patients. At present, the only effective way to treat cataract is surgery. After years of development, phacoemulsification combined with intraocular lens implantation has become the most commonly used cataract surgery method. As we all know, any operation will cause damage to the body's cells, so viscoelastics are often used as auxiliary materials for ophthalmic surgery to temporarily support the surgical space, protect the tissue from mechanical damage by surgical instruments, and facilitate the smooth impleme...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61L31/00A61L31/14A61L31/04A61L31/16
CPCA61L31/00A61L31/042A61L31/043A61L31/14A61L31/16A61L2300/10A61L2300/404C08L5/08
Inventor 耿慧敏解江冰
Owner EYEBRIGHT MEDICAL TECH BEIJING
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com