Anhydrous compositions containing hydroxylated diphenylmethane derivatives

A technology of hydroxylated diphenylmethane and anhydrous compositions, applied in the field of anhydrous compositions, can solve the problems of greasy feeling and unsatisfactory formulations

Active Publication Date: 2021-08-13
LOREAL SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, it is still unsatisfactory
The inventors have found that when using agents that increase the solubility and stability of the active substance, the formulation exhibits a greasy feel after application

Method used

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  • Anhydrous compositions containing hydroxylated diphenylmethane derivatives
  • Anhydrous compositions containing hydroxylated diphenylmethane derivatives
  • Anhydrous compositions containing hydroxylated diphenylmethane derivatives

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0050] According to a preferred embodiment of the present invention, in the compound of formula (I):

[0051] - R1, R2, R4 and R5 represent hydrogen atoms;

[0052] -R3 is methyl;

[0053] - said -OH groups are in the ortho and para positions with respect to the bond formed with the carbon connecting the two aromatic rings to each other.

[0054] This compound corresponds to the following formula (II)

[0055]

[0056] It is called 4-(1-phenylethyl)-1,3-benzenediol (that is, 4-(1-phenylethyl)-1,3-dihydroxybenzene), or phenylethylresorcinol ( ie phenylethylquinone or styrylresorcinol). The CAS number of this compound is 85-27-8.

[0057] These compounds are manufactured by Symrise (SYMRISE) under the name of SYMWHITE or under the name BIO 377.

[0058] In the composition according to the invention, the amount of diphenylmethane compound according to one of the formulas (I) or (II) is in particular 0.001% to 5%, preferably 0.01% to 5% by weight relative to the total we...

Embodiment 1

[0172] Embodiment 1: the preparation of formula of the present invention and comparative formula

[0173] Formula of the present invention and comparative formula are prepared in the following manner (expressed in weight percent relative to the total weight of the composition)

[0174]

[0175]

[0176]

[0177] Comparative formulations 1 to 3 were formulated with ingredient a) different from the present invention, and due to the hydrophilic nature of this ingredient, surfactants and water were used;

[0178] Comparative formula 4 and 5 do not contain component b) or c) of the present invention respectively;

[0179] Comparative formulation 6 contained isopropyl N-lauroyl sarcosinate instead of component b) of the present invention.

[0180] The compositions are prepared in a manner known to those skilled in the art.

[0181] Basically, mix Phase A and heat to 75°C.

[0182] Optionally, when Phase D is present, mix Phase D and heat to 75°C.

[0183] Alternatively,...

Embodiment 2

[0186] Embodiment 2: the evaluation of formula of the present invention and comparative formula

[0187] After one month of storage, stability tests were performed at 4°C, 25°C, 40°C or 45°C.

[0188] The stability test adopts sunshine test, and implements multiple rounds.

[0189] The embodiment of the stability sunlight test is that the formula of the present invention and the comparative formula are placed in the Suntest CPS+ testing device produced by Atlas (Atlas) for 24 hours.

[0190] Each round of stability testing was performed for 10 days, with the temperature changing from -20°C to 20°C every 24 hours.

[0191] In addition, cosmetic properties such as greasy feeling after application were evaluated by 5 subjects applying the formulation of the present invention and the comparative formulation to their skins and giving scores at the time of application and immediately after application.

[0192] 5 points: Excellent skin care feeling without any greasy feeling;

[...

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Abstract

A composition comprising in a physiologically acceptable medium: (a) at least one hydroxylated diphenylmethane derivative of formula (I) (b) at least one derivative of formula R 1 COOR 2 of fatty acid esters, where, R 1 Indicates fatty acid residues containing 6 to 29 carbon atoms, R 2 means a branched or unbranched hydrocarbon chain containing from 3 to 30 carbon atoms; and (c) at least one fatty acid triglyceride, each of which independently has from 3 to 30 carbon atoms. A method of caring for or making up the skin comprising topically applying such compositions to the skin.

Description

technical field [0001] The present invention relates to anhydrous compositions, in particular to anhydrous compositions for the care and / or makeup of keratin materials comprising at least one hydroxylated diphenylmethane derivative of the formula (I). [0002] Background technique [0003] Active substances such as whitening agents are known in cosmetic and / or dermatological compositions for the purpose of whitening keratinous materials, especially the skin. For example, ascorbyl glucoside, 3-O-ethyl ascorbic acid, nicotinamide or hydroxylated diphenylmethane derivatives are compounds known in the field of cosmetics to have whitening effects and are widely used in cosmetic emulsions. [0004] In addition, cosmetic oils, especially anhydrous oils, are well known to consumers as an effective skin care product. Its aesthetic appearance (preferably transparent appearance) and the skin feeling after application make these products very popular among consumers, especially thos...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/34A61K8/37A61Q19/02
CPCA61K8/347A61K8/37A61K8/375A61K2800/262A61K2800/31A61Q19/02
Inventor 乐玮蒂埃里·戈登陈瑞俊
Owner LOREAL SA
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