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Preparation method of traditional Chinese medicine composition for septicemia prevention

A composition and sepsis technology, applied in the direction of pharmaceutical formula, medical preparations containing active ingredients, antibacterial drugs, etc., can solve the problems of large side effects, unsatisfactory preventive effect, complicated process, etc., achieve low side effects and prevent sepsis , The effect of simple process

Inactive Publication Date: 2018-11-13
周万芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, although the preparation of drugs for the prevention of sepsis has been done, the process is complicated, and most of the obtained drugs are chemical drugs, which have the disadvantages of large side effects and unsatisfactory preventive effects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Party:

[0023] 10 parts of Prunella vulgaris, 5 parts of light bamboo leaves, 20 parts of Coptis chinensis, 10 parts of Sanqi, 25 parts of ginseng, 5 parts of Houttuynia cordata, 20 parts of Daqingye, 5 parts of sea pumice, and 25 parts of Trichosanthes.

[0024] Preparation:

[0025] (1) Take Prunella vulgaris, leaves of bamboo, Coptis chinensis, Panax notoginseng and ginseng, add 6 times the volume of 80% ethanol, reflux extraction 3 times, each time for 2 hours, combine the extracts, concentrate to obtain liquid extract A;

[0026] (2) Take Houttuynia cordata, Daqingye, sea pumice and Trichosanthes, add 8 times the volume of pure water, heat to boil, reflux and extract 3 times, each time for 2 hours, combine the extracts, concentrate to obtain liquid extract B;

[0027] (3) Combine and mix the above liquid extract A and liquid extract B, and place at room temperature for 24 hours;

[0028] (4) Filtrate and add conventional auxiliary materials to make a liquid prep...

Embodiment 2

[0030] Party:

[0031] 10 parts of Prunella vulgaris, 25 parts of Bamboo Leaf, 10 parts of Coptis chinensis, 30 parts of Panax notoginseng, 15 parts of ginseng, 35 parts of Houttuynia cordata, 10 parts of Daqingye, 25 parts of sea pumice, 10 parts of Trichosanthes.

[0032] Preparation:

[0033] (1) Take Prunella vulgaris, leaves of bamboo, Coptis chinensis, Panax notoginseng and ginseng, add 10 times the volume of 80% ethanol, reflux extraction 3 times, each time for 4 hours, combine the extracts, concentrate to obtain liquid extract A;

[0034] (2) Take Houttuynia cordata, Daqingye, sea pumice and Trichosanthes, add 12 times the volume of pure water, heat to boil, reflux and extract 3 times, each time for 4 hours, combine the extracts, and concentrate to obtain liquid extract B;

[0035] (3) Combine and mix the above-mentioned liquid extract A and liquid extract B, and place at room temperature for 48 hours;

[0036] (4) Filtrate and add conventional auxiliary materials to...

Embodiment 3

[0038] Party:

[0039] 10 parts of Prunella vulgaris, 5 parts of light bamboo leaves, 10 parts of Coptis chinensis, 10 parts of Panax notoginseng, 15 parts of ginseng, 5 parts of Houttuynia cordata, 10 parts of Daqingye, 5 parts of sea pumice, and 10 parts of Trichosanthes.

[0040] Preparation:

[0041] (1) Take Prunella vulgaris, leaves of bamboo, Coptis chinensis, Panax notoginseng and ginseng, add 8 times the volume of 80% ethanol, reflux extraction 3 times, each time for 3 hours, combine the extracts, concentrate to obtain liquid extract A;

[0042] (2) Take Houttuynia cordata, Daqingye, sea pumice and Trichosanthes, add 10 times the volume of pure water, heat to boil, reflux and extract 3 times, each time for 3 hours, combine the extracts, concentrate to obtain liquid extract B;

[0043] (3) Combine and mix the above liquid extract A and liquid extract B, and place at room temperature for 36 hours;

[0044] (4) Filtrate and add conventional auxiliary materials to make ...

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine composition for septicemia prevention. The preparation method includes steps: (1) taking Spica Prunellae, Herba Lophatheri, Rhizoma Coptidis, Radix Notoginseng and Radix Ginseng, adding 6-10 volumetric times of 80% ethyl alcohol, performing reflux extraction for 3 times and for 2-4 hours each time, combining extract liquid, and concentrating to obtain liquid extract A; (2) taking Herba Houttuyniae, Folium Isatidis, pumice and Fructus Trichosanthis, adding 8-12 volumetric times of pure water, heating, boiling, performing reflux extraction for 3 times and for 2-4 hours each time, combining extract liquid, and concentrating to obtain liquid extract B; (3) combining the liquid extract A and the liquid extract B, well mixing, and standing for 24-48h at the normal temperature; (4) filtering, and adding conventional auxiliary materials to obtain a liquid preparation or a solid preparation. Compared with the prior art, the preparation method has advantages of simple process, low cost and effectiveness in integration of raw materials; the obtained traditional Chinese medicine composition is simple in formula, precise in compatibility, accurate in dosage, effective in septicemia prevention, excellent in efficacy, low in side effect and high in patient adaptability.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition for preventing sepsis, and belongs to the technical field of traditional Chinese medicine preparations. Background technique [0002] Septicemia refers to the acute systemic infection caused by pathogenic bacteria or opportunistic pathogenic bacteria invading the blood circulation, growing and multiplying in the blood, and producing toxins. If the bacteria invading the bloodstream are cleared by the body's defense function and there is no obvious symptom of toxemia, it is called bacteremia. Sepsis with multiple abscesses and a longer course is called sepsis (pyemia). If sepsis is not controlled quickly, it can develop from the primary infection site to other parts of the body, causing metastatic abscess. Abscesses can occur on the surface of the brain, causing meningitis, on the envelope surrounding the heart, causing pericarditis, on the lining of the heart, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P31/04A61K33/00
CPCA61K36/899A61K33/00A61K36/195A61K36/258A61K36/315A61K36/428A61K36/536A61K36/704A61K36/718A61K36/78A61K36/855A61K2300/00
Inventor 周万芳
Owner 周万芳
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