Immunoquantitation analyzer

Abstract

The invention provides an immunoquantitation analyzer which mainly consists of the following components: a reagent card moving mechanism, a dosing device, a detection structure, a liquid path system,a waste cabin mechanism and a rack structure. By adopting the immunoquantitation analyzer provided by the invention, effects of high-flux detection, high detection precision and stable and reliable detection data can be achieved, and in addition, the analyzer is simple in overall structure and small in size.

Description

technical field [0001] The invention relates to the detection field, in particular to a detection instrument. Background technique [0002] At present, most of the immunochromatographic analyzers on the market are divided into two categories, one is semi-automatic instruments, the process of adding samples, dilution, and chromatographic reactions is completed outside the machine, the throughput of such instruments is low, the detection speed is slow, and manual operation It is complex and requires high professionalism of operators. It is difficult to guarantee the consistency and accuracy of dilution and sample addition. The result deviation is large and it is easy to cause pollution. Fully automatic instruments often adopt the method of batch sampling and card feeding, and complete sample addition and reaction testing in the machine. The existing automatic immune analyzers have the following problems: 1. Batch feeding requires multiple reagent cards to be placed in a fixed ...

AI Technical Summary

Problems solved by technology

[0002] At present, most of the immunochromatographic analyzers on the market are divided into two categories, one is semi-automatic instruments, the process of adding samples, dilution, and chromatographic reactions is completed outside the machine, the throughput of such instruments is low, the detection speed is slow, and manual operation It is complex and requires high professionalism of operators. It is difficult to guarantee the consistency and accuracy of dilution and sample addition. The result deviation is large and it is easy to cause pollution. Fully automatic instruments often adopt the method of batch sampling and card feeding, and complete sample addition and reaction testing in the machine. The existing automatic immune analyzers have the following problems: 1. Batch feeding requires multiple reagent cards to be placed in a fixed place in advance. Among the containers, if the reagent card is not used up on the same day, the reaction result will be affected after the reagent card is damp the next day; 2. Due to the limited number of fixed containers for the reagent card, the instrument only supports 3 to 4 items of testing at a time, and the throughput is low; 3. In addition, many instruments use the tip head sampling method, which cannot support micro-sample sampling, and the use and maintenance costs are high, and manual operation is complicated; 4. When the reagent card has a large delivery distance, the delivery mechanism generally adopts a belt drive structure , when manually inserting the reagent card, the holding torque (static torque) of the motor is required to be relatively large, otherwise the reagent card holder will move when the reagent card is inserted, resulting in poor transmission accuracy, poor stability, and easy occurrence of stuck reagent cards, etc. question

In order to avoid the above problems, the size of the motor of some immune analyzers is relatively large, so that the motor has a larger holding torque, but it will make the immune analyzer larger and take up space; 5. Most of the reagent cards are collected manually Waste card, the operation process is relatively cumbersome, and some immune analyzers are equipped with a card kicking mechanism. The card kicking principle is: when the reagent card moves to a preset kicking position, the kicking mechanism starts to intervene, and through the motor drive, Drive the movement of the parts of the card kicking mechanism, thereby kicking the reagent card out of the card holder

Due to the addition of a kicking mechanism in the immune analyzer, the overall structure of the instrument will become complex and bloated, the volume will be larger, the assembly difficulty will be increased, and the production cost will be high; 6. Immunochromatographic analysis technology requires detection speed and stability Very high, the current immunochromatographic analysis instruments on the market usually use monochromatic light to irradiate the color window of the test strip, and then use the linear CCD to collect the color information in the window, and then identify and analyze the image. This method can only collect A piece of test strip information is also used to detect the test strip with the CIS detection head to draw the signal intensity curve of the tracer for data analysis. This method can detect multiple test strips at a time, but the speed of obtaining signals is slow and generates The image has fewer effective pixels and the edges are blurred; there is another solution, which provides light for multiple test strips arranged in parallel and spaced intervals through the light source and takes pictures and detects them. However, the test strips in the middle receive higher light intensity, and the middle Going to the edge position, the closer to the edge position, the intensity of light received will gradually weaken, and there will be mutual interference between different light sources, resulting in low accuracy of test strip information analysis; 7. Although the existing general immune quantitative analyzers are It uses automatic sample addition, but when the concentration of the sample is too high, manual dilution is used when diluting the sample, which not only prolongs the detection time, but also when a patient with a sudden disease needs to detect a certain indicator immediately, Manual dilution of the sample significantly prolongs the detection time, and the result may be that the patient cannot get the right medicine, and manual dilution is likely to cause errors in the test results, which is also unfavorable for the diagnosis of the disease

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