CircRNA related to subcutaneous fat of pigs and application thereof

A technology of subcutaneous fat and pig skin, applied in DNA/RNA fragments, recombinant DNA technology, determination/inspection of microorganisms, etc., can solve problems such as unclear
CN108893541AActive Publication Date: 2018-11-27INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI
Publication Date
2018-11-27

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Abstract

The invention relates to a circRNA related to subcutaneous fat of pigs and an application thereof, and specifically relates to a circRNA_11897 related to subcutaneous fat of pigs and the application thereof. The invention identifies and analyzes the circRNA of the subcutaneous fat of large white pigs and Laiwu pigs, adopts a systematic bioinformatic method for performing functional analysis on thedifferential expression circRNA and finds the circRNA_11897 and the genes ssc-miR-27a, ssc-miR-27b-3p and SCD related to the circRNA_11897. The experiment proves that the expression quantity of the circRNA_11897 and the genes has a close relation with the subcutaneous fat of pigs. The invention provides a new theoretical basis and a potential target for improving the quality of pork and preventing the happening of metabolic diseases caused by dyslipidemia.
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Description

technical field

[0001] The present invention relates to the field of biotechnology, in particular to a pig subcutaneous fat-related circular RNA and its application, more specifically to circRNA_11897 and its application. Background technique

[0002] The quality of pork is closely related to human health. Excessive deposition of subcutaneous fat will increase the content of cholesterol and reduce the quality of pork. Consumers will easily lead to obesity after ingestion. Therefore, understanding the molecular mechanism of fat deposition will help improve the quality of pork. Pork quality and human health. Large white pig, as a typical lean pig, has low subcutaneous fat; while Laiwu pork has bright red color, good water holding capacity, high fat content, and excellent meat quality. Therefore, the significant difference in fat deposition between Large White and Laiwu pigs provides a good model for the study of fat metabolism.

[0003] circRNA is a kind of circular endogeno...

Claims

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