Slab PET limited angle molecular image positioning system and method
A positioning system and molecular imaging technology, applied in the medical field, can solve the problems of target point position change and inaccurate positioning, and achieve the effect of generating small noise, overcoming image deformation, and increasing the number of iterations.
Pending Publication Date: 2018-12-18
北京锐视康科技发展有限公司
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[0005] In order to solve the problems of inaccurate positioning and changes in the position of the target point in the existing intraoperative PET positioning process, the present invention proposes a flat-panel PET limited-angle molecular image positioning system and its positioning method. The flat-panel PET can be realized without rotation. Fast imaging and real-time positioning of target points in molecular imaging
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[0033] The present invention will be further elaborated below through specific embodiments in conjunction with the accompanying drawings.
[0034] like figure 1 As shown, the flat-panel PET limited-angle molecular imaging system of this embodiment includes: an imaging bed 1, an imaging bracket, a pair of flat-panel PET (5 and 6), a visible light source, a motor, and a computer; wherein, the imaging sample is located on the imaging bed 1 A pair of flat-panel PETs (5 and 6) are opposite, and without mechanical rotation, are installed on the imaging support, the imaging support includes a mobile frame 2 and a connecting arm 3, and the connecting arm 3 adopts a C-arm, and the imaging sample is located between a pair of flat-panel PETs. In the middle, and the acquisition angle of the flat-panel PET is ≥90°, the xyz coordinate system is established with the rotation center 4 of a pair of flat-panel PETs as the coordinate origin; the pair of flat-panel PETs are connected to the compu...
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The invention discloses a slab PET limited angle molecular image positioning system and method. The method comprises the steps that an imaging sample is placed between a pair of slab PETs without mechanical rotation; a pair of visible light generators emit two visible light beams, the angles of the two visible light beams are synchronously controlled through a motor, the intersection point of thetwo visible light beams is located on the surface of the imaging sample, and the position of the intersection point is worked out and stored by a computer; the positions of the pair of slab PETs are kept unchanged, and PET data is collected and transmitted to the computer; through a combination algorithm of an expectation maximization algorithm EM and a total variation minimization algorithm TV ofthe computer, the difficulties of image deformation and large image noise caused by angle deficiency are overcome, a PET reconstructed image is obtained, then the intersection point of the two visible light beams is fused into the PET reconstructed image, displayed in a fake bright spot mode and fused with optical information, and with the intersection point as a reference point, target points inthe imaging sample are directly displayed and visually positioned.
Description
technical field [0001] The invention relates to the field of medical technology, in particular to a flat-panel PET limited-angle molecular image positioning system and a positioning method thereof. Background technique [0002] Positron Emission Tomography (PET) is a non-invasive molecular medical imaging technology that can noninvasively, quantitatively and dynamically reflect metabolism, biochemical reactions, functional activity and perfusion levels in vivo. Because the glucose metabolism of malignant tumor cells is much higher than that of normal tissue cells, PET is widely used in clinical imaging diagnosis of malignant tumors. With the development of science and technology, tumors are increasingly becoming the biggest threat to human life. Surgery is one of the oldest and most effective methods of treating tumors. Tumors are generally located within the body, so localization of tumors before and during surgery is of great significance. [0003] With the deepening of...
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IPC IPC(8): A61B6/03A61B6/04
CPCA61B6/037A61B6/0407A61B6/40A61B6/5217A61B6/5258
Inventor 刘力熊先华曾海宁张占军赵明王婷
Owner 北京锐视康科技发展有限公司