Anti-tumor traditional Chinese medicinal composition based on ancient prescription Tuoli Xiaodu Powder, and preparation method and application thereof

An anti-tumor effect and composition technology, which is applied in the direction of anti-tumor drugs, drug combinations, medical preparations containing active ingredients, etc., can solve problems such as no anti-tumor application reports, and achieve self-immunity improvement without toxicity Side effects, the effect of inhibiting the growth of cancer cells

Pending Publication Date: 2018-12-18
SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Tuoli Xiaodusan is a famous ancient prescription of traditional Chinese medicine for treating surgical sores, but there is no report about its application in antitumor

Method used

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  • Anti-tumor traditional Chinese medicinal composition based on ancient prescription Tuoli Xiaodu Powder, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] 1. A traditional Chinese medicine composition with anti-tumor effect, consisting of the following raw materials in parts by weight: 30 parts of Codonopsis pilosula, 30 parts of Astragalus membranaceus, 20 parts of Poria cocos, 20 parts of Atractylodes macrocephala, 5 parts of roasted licorice, 20 parts of white peony root, 10 parts of angelica 10 parts of Chuanxiong, 10 parts of Campanulaceae, 10 parts of Angelica dahurica, 30 parts of saponins, and 30 parts of Hedyotis diffusa.

[0054] 2. A decoction of a Chinese medicine composition with antitumor effect, the preparation method of which comprises the following steps:

[0055] Take Codonopsis 30g, Radix Astragali 30g, Poria cocos 20g, Atractylodes macrocephala 20g, Radix Glycyrrhizae 6g, Radix Paeoniae Alba 20g, Angelica 10g, Rhizoma Chuanxiong 10g, Campanulaceae 10g, Angelica dahurica 10g, Saponaria thorn 30g, Hedyotis diffusa according to the parts by weight described in step 1. Grass 30g, add 10 times the weight of...

Embodiment 2

[0057] 1. A traditional Chinese medicine composition with anti-tumor effect, consisting of the following raw materials in parts by weight: 28 parts of Codonopsis pilosula, 25 parts of Astragalus membranaceus, 20 parts of Poria cocos, 15 parts of Atractylodes macrocephala, 5 parts of roasted licorice, 15 parts of white peony root, 10 parts of angelica 10 parts of Chuanxiong, 8 parts of Bellflower, 8 parts of Angelica dahurica, 20 parts of saponins, and 25 parts of Hedyotis diffusa.

[0058] 2. An oral liquid of a traditional Chinese medicine composition with antitumor effect, the preparation method of which comprises the following steps:

[0059] S1. Take Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome and Chinese Angelica Sinensis according to the parts by weight described in the above-mentioned Chinese medicine composition, add 10 times the weight of water and soak for 2 hours, then distill and extract 3 times, each time for 4 hours, to obtain its volatile oil c...

Embodiment 3

[0064] 1. A traditional Chinese medicine composition with anti-tumor effect, consisting of the following raw materials in parts by weight: 23 parts of Codonopsis pilosula, 22 parts of Astragalus membranaceus, 18 parts of Poria cocos, 13 parts of Atractylodes macrocephala, 4 parts of roasted licorice, 18 parts of white peony root, 8 parts of angelica 8 parts of Chuanxiong, 8 parts of Campanulaceae, 8 parts of Angelica dahurica, 25 parts of saponins, and 20 parts of Hedyotis diffusa.

[0065] 2. A granule of a traditional Chinese medicine composition with anti-tumor effect, the preparation method of which comprises the following steps:

[0066] S1. Take Atractylodes Rhizoma Atractylodes Rhizome and Angelica Sinensis according to the parts by weight described in the above-mentioned Chinese medicine composition, add 8 times the weight of water to soak for 2 hours, then distill and extract 3 times, each time for 3 hours, to obtain its volatile oil components;

[0067] S2. Add Codon...

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Abstract

The invention discloses a traditional Chinese medicinal composition with an anti-tumor effect. The traditional Chinese medicinal composition is composed of the following components by weight: 15 to 30parts of Radix codcnopsitis, 15 to 30 parts of milkvetch roots, 10 to 20 parts of Poria cocos, 10 to 20 parts of bighead atractylodes rhizomes, 3 to 6 parts of honey-fried licorice roots, 10 to 20 parts of Radix Paeoniae Alba, 5 to 10 parts of Chinese angelica roots, 5 to 10 parts of Ligusticum wallichii, 5 to 10 parts of Radix Platycodonis, 5 to 10 parts of Radix Angelicae, 15 to 30 parts of Chinese honeylocust spine and 15 to 30 parts of Oldenlandia diffusa. The traditional Chinese medicinal composition provided by the invention has the following advantages: an ancient prescription, namely,Tuoli Xiaodu Powder, is improved and innovatively applied to treatment of malignant tumors; directed at different tumors, syndrome differentiation and treatment are adopted for proportioning and formulation; and clinical experiment results show that the traditional Chinese medicinal composition provided by the invention has good therapeutic effects on a variety of malignant tumors like breast cancer, liver cancer, lung cancer, colon cancer, gastric cancer, ovarian cancer, cervical cancer and endometrial cancer, has significant curative effects on patients with multiple tumors, recurrent tumors and postoperative metastasis, is wide in an application range, free of obvious adverse reactions in clinical practice and safe and reliable in medication, improves the life quality of a terminal cancer patient, and is expected to be developed into a novel anti-tumor traditional Chinese medicine.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and more specifically relates to an anti-tumor traditional Chinese medicine composition based on Gufang Tuoli Xiaodusan and its preparation method and application. Background technique [0002] Malignant tumors have become a health killer that seriously threatens human life. There are about 2 million new patients with malignant tumors in China every year, and more than 1.5 million people die of cancer every year. Therefore, the prevention and treatment of malignant tumors has become a difficult problem that has been widely valued worldwide. At present, the treatment of malignant tumors mainly includes surgery, radiotherapy, chemotherapy and biological treatment. The cost of treatment is high, many families are impoverished due to illness, and the side effects after treatment are large, recurrence is easy, the patient is extremely painful, and the quality of life is extremely low. [00...

Claims

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Application Information

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IPC IPC(8): A61K36/748A61P35/00A61P35/04
CPCA61K36/076A61K36/232A61K36/236A61K36/284A61K36/344A61K36/346A61K36/481A61K36/483A61K36/484A61K36/65A61K36/71A61K36/748A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61P35/00A61P35/04A61K2300/00
Inventor 梁俊雄吴芬芳
Owner SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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